7 completed, 3 terminated, 1 not yet recruiting, 1 unknown. 12 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 7, Terminated 3, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 4 | Completed 2, Terminated 1, Unknown 1 |
Follow Gallbladder Cancer: new trials by email Literature Review of Gallbladder Cancer trials Research Report on Gallbladder Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hepatic Arterial Infusion Chemotherapy Versus Capecitabine as Adjuvant Therapy for Resected Biliary Tract Cancer Oxaliplatin, 5-Fluorouracil, Capecitabine - Biliary Tract Cancer, Cholangiocarcinoma | Phase 3 | Not yet recruiting | Zhai Wenlong | 90 | 2026-11-30 | 2026-11-04 |
| Addition of Everolimus to Standard of Care in Carcinoma Gallbladder Everolimus 10 mg, Standard of care - Gallbladder Cancer | Phase 2 / Phase 3 | Unknown | Banaras Hindu University | 56 | 2022-11-01 | 2024-08-13 |
| Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC M7824, Placebo, Gemcitabine - Biliary Tract Cancer, Cholangiocarcinoma | Phase 2 / Phase 3 | Terminated | EMD Serono Research & Development Institute, Inc. | 309 | 2019-09-20 | 2023-11-14 |
| Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers Active Symptom Control, L-folinic acid, 5 FU - Biliary Tract Cancer, Gallbladder Cancer | Phase 3 | Completed | The Christie NHS Foundation Trust | 162 | 2014-02-01 | 2020-01-28 |
| Gemcitabine Hydrochloride and Oxaliplatin or Observation in Treating Patients With Biliary Tract Cancer That Has Been Removed by Surgery gemcitabine hydrochloride, oxaliplatin, clinical observation - Extrahepatic Bile Duct Cancer, Gallbladder Cancer | Phase 3 | Completed | UNICANCER | 190 | 2009-07-01 | 2017-01-25 |
| Gemcitabine With/Out Capecitabine in Locally Advanced, Unresectable, or Metastatic Biliary Cancer capecitabine, gemcitabine hydrochloride, quality-of-life assessment - Extrahepatic Bile Duct Cancer, Gallbladder Cancer | Phase 3 | Terminated | NCIC Clinical Trials Group | 19 | 2008-10-10 | 2023-08-04 |
| Biliary Stenting With or Without Photodynamic Therapy in Treating Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma or Other Biliary Tract Tumors That Cannot Be Removed by Surgery porfimer sodium, biliary stenting - Extrahepatic Bile Duct Cancer, Gallbladder Cancer | Phase 3 | Completed | University College, London | 92 | 2007-07-01 | 2013-02-20 |
| Escitalopram in Treating Depression in Patients With Advanced Lung or Gastrointestinal Cancer escitalopram oxalate, Placebo - Colorectal Cancer, Depression | Phase 3 | Terminated | Massachusetts General Hospital | 24 | 2006-03-01 | 2012-12-03 |
| Capecitabine or Observation After Surgery in Treating Patients With Biliary Tract Cancer capecitabine, clinical observation, adjuvant therapy - Extrahepatic Bile Duct Cancer, Gallbladder Cancer | Phase 3 | Completed | University Hospital Southampton NHS Foundation Trust | 360 | 2006-03-01 | 2013-08-26 |
| Palliative Biliary Stenting on the Quality of Life of Patients With Unresectable Carcinoma Gallbladder With Hiliar Block. Biliary stenting - Gallbladder Cancer | Phase 2 / Phase 3 | Completed | All India Institute of Medical Sciences | 60 | 2006-01-01 | 2013-07-11 |
| Fluorouracil, Cisplatin, and Radiation Therapy or Gemcitabine and Oxaliplatin in Treating Patients With Nonmetastatic Biliary Tract Cancer That Cannot Be Removed By Surgery cisplatin, gemcitabine hydrochloride, oxaliplatin - Extrahepatic Bile Duct Cancer, Gallbladder Cancer | Phase 2 / Phase 3 | Completed | Federation Francophone de Cancerologie Digestive | 34 | 2005-10-01 | 2016-05-30 |
| Gemcitabine With or Without Cisplatin in Treating Patients With Unresectable Locally Advanced or Metastatic Cholangiocarcinoma or Other Biliary Tract Tumors cisplatin, gemcitabine hydrochloride - Extrahepatic Bile Duct Cancer, Gallbladder Cancer | Phase 3 | Completed | University College, London | 324 | 2005-05-01 | 2012-07-17 |
Gallbladder Neoplasms (12) · Bile Duct Neoplasms (7) · Liver Neoplasms (5) · Biliary Tract Neoplasms (3) · Cholangiocarcinoma (3) · Carcinoma, Hepatocellular (2) · Camurati-Engelmann Syndrome (1) · Carcinoma, Non-Small-Cell Lung (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Depression (1) · Esophageal Neoplasms (1) · Fatigue (1) · Lung Neoplasms (1) · Pancreatic Neoplasms (1)
Biliary Tract Diseases (12) · Digestive System Diseases (12) · Digestive System Neoplasms (12) · Gallbladder Diseases (12) · Neoplasms (12) · Neoplasms by Site (12) · Biliary Tract Neoplasms (9) · Bile Duct Diseases (7) · Adenocarcinoma (5) · Carcinoma (5) · Liver Diseases (5) · Neoplasms by Histologic Type (5) · Neoplasms, Glandular and Epithelial (5) · Behavior (1) · Behavioral Symptoms (1)
Gemcitabine (5) · Oxaliplatin (4) · Capecitabine (3) · Cisplatin (3) · Chemotherapy, Adjuvant (2) · Fluorouracil (2) · Watchful Waiting (2) · Dihematoporphyrin Ether (1) · Drug Therapy (1) · Escitalopram (1) · Everolimus (1) · Leucovorin (1) · Standard of Care (1)
University College, London (2) · All India Institute of Medical Sciences (1) · Banaras Hindu University (1) · EMD Serono Research & Development Institute, Inc. (1) · Federation Francophone de Cancerologie Digestive (1) · Massachusetts General Hospital (1) · NCIC Clinical Trials Group (1) · The Christie NHS Foundation Trust (1) · UNICANCER (1) · University Hospital Southampton NHS Foundation Trust (1) · Zhai Wenlong (1)
United Kingdom (5) · France (3) · China (2) · India (2) · United States (2) · Argentina (1) · Australia (1) · Brazil (1) · Canada (1) · Chile (1) · Germany (1) · Italy (1) · Japan (1) · Poland (1) · South Korea (1)
Bruno Chauffert (1) · Clive Stubbs (1) · Eveline Boucher, MD (1) · Jennifer Knox, MD (1) · John A. Bridgewater (1) · Juan Valle, Prof (1) · Pramod Garg, M.D, D.M. (1) · Stephen P. Pereira, MD (1) · Vikram Bhatia, M.D, D.M. (1) · William F. Pirl, MD (1)
PMID 20375404, PMID 25241229, PMID 32461347, PMID 33798493, PMID 38661512, PMID 38875119, PMID 41887529
2019 (1), K23CA115908 (1)