6 completed, 4 terminated, 2 unknown, 1 not yet recruiting. 14 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 6, Terminated 4, Unknown 2, Not yet recruiting 1, Recruiting 1 |
Follow Fractures, Open: new trials by email Literature Review of Fractures, Open trials Research Report on Fractures, Open
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries Accelerated Flap Coverage Surgery, Standard of Care Flap Timing - Open Tibia Fracture, Open Dislocation of Ankle | Not applicable | Not yet recruiting | Johns Hopkins University | 356 | 2027-01-01 | 2026-09-18 |
| Evaluation of STIMULAN Device and AI Model in Preventing Fracture Infections STIMULAN - Open Fracture | Not applicable | Unknown | Università Vita-Salute San Raffaele | 40 | 2023-11-01 | 2024-04-25 |
| LOQTEQ® Antibacterial Pre-Market Study Implantation - Fractures, Open, Fractures, Closed | Not applicable | Completed | aap Implantate AG | 203 | 2021-12-09 | 2025-09-18 |
| FastFrame Knee Spanning and Damage Control Kit PMCF FastFrame External Fixation System - Knee Spanning or Damage Control Kit - Fracture, Fractures, Bone | Not applicable | Terminated | Zimmer Biomet | 33 | 2021-06-18 | 2025-02-10 |
| Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial Cognitive Behavioural Therapy - Pain, Postoperative, Pain, Acute | Not applicable | Completed | McMaster University | 1024 | 2021-01-25 | 2025-09-05 |
| Impact of Psychoeducational Video on Adjustment to Open Fracture. Video Viewing - Major Trauma | Not applicable | Terminated | Oxford University Hospitals NHS Trust | 22 | 2020-12-03 | 2023-01-13 |
| A Prospective Randomized Controlled Study on the Clinical Efficacy of a New Surface Modified Composite Coating Orthopedic Implant Device Surface-modified composite coated orthopedic implants, conventional orthopedic implants - Open Fractures, Degenerative Osteoarthritis and Degenerative Spinal Diseases | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 240 | 2020-10-01 | 2020-07-22 |
| Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Pilot Cognitive Behavioural Therapy - Pain, Postoperative, Fractures, Open | Not applicable | Terminated | McMaster University | 83 | 2019-01-09 | 2020-01-29 |
| Cognitive Behavioural Therapy to Reduce Persistent Post-Surgical Pain After Fracture Cognitive behavioural therapy - Pain, Postoperative, Fractures, Closed | Not applicable | Terminated | McMaster University | 8 | 2018-10-01 | 2020-02-24 |
| Study Evaluating CERAMENT™|G in Open Diaphyseal Tibial Fractures CERAMENT|G, SOC treatment - Tibial Fracture | Not applicable | Completed | BONESUPPORT AB | 201 | 2017-02-14 | 2021-08-10 |
| Safety and Performance of BonyPid-1000™ in the Treatment of Gustilo I, II, IIIA and IIIB Tibial Open Fractures BonyPid-1000, Standard of Care (SOC) treatment - Tibial Fractures, Open Fractures | Not applicable | Completed | PolyPid Ltd. | 51 | 2015-10-01 | 2020-05-19 |
| The Treatment of Type I Open Fractures in Pediatrics Formal Operative Treatment, Emergency Department Treatment - Fractures, Open | Not applicable | Recruiting | Ann & Robert H Lurie Children's Hospital of Chicago | 300 | 2010-03-01 | 2026-07-01 |
| Percutaneous Autologous Bone-marrow Grafting for Open Tibial Shaft Fracture Osteosynthesis - Tibial Fractures, Fractures, Open | Not applicable | Completed | University Hospital, Tours | 85 | 2007-09-01 | 2018-10-22 |
| Vacuum Assisted Closure as a Treatment for Open Fractures Standard Wound Dressing, VAC - Orthopaedic Traumatic Open Fractures | Not applicable | Completed | University of Alabama at Birmingham | 63 | 2001-06-01 | 2013-08-14 |
Fractures, Closed (5) · Fractures, Bone (4) · Pain, Postoperative (3) · Tibial Fractures (3) · Acute Pain (1) · Chronic Pain (1) · Fibula Fractures (1) · Joint Diseases (1) · Leg Injuries (1) · Surgical Wound Infection (1) · Wounds and Injuries (1)
Wounds and Injuries (13) · Fractures, Bone (10) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Postoperative Complications (4) · Leg Injuries (3) · Neurologic Manifestations (3) · Pain (3) · Signs and Symptoms (3) · Infections (1) · Musculoskeletal Diseases (1) · Wound Infection (1)
Cognitive Behavioral Therapy (3) · Fracture Fixation, Internal (1) · Negative-Pressure Wound Therapy (1) · Standard of Care (1) · Therapeutics (1)
McMaster University (3) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · BONESUPPORT AB (1) · Johns Hopkins University (1) · Oxford University Hospitals NHS Trust (1) · PolyPid Ltd. (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · University Hospital, Tours (1) · University of Alabama at Birmingham (1) · Università Vita-Salute San Raffaele (1) · Zimmer Biomet (1) · aap Implantate AG (1)
United States (6) · Canada (3) · Germany (2) · United Kingdom (2) · France (1) · Israel (1) · Italy (1) · Philippines (1) · Poland (1)
Jason Busse, PhD (2) · Sheila Sprague, PhD (2) · Douglas R. Dirschl, MD (1) · Erin Osborn (1) · May Quarmby, D Clin (1) · Philippe Rosset, Pr (1) · Rena L Stewart, MD (1) · Shany Blum, Dr. (1) · Volker Alt, Prof. Dr. (1)
PMID 36273187, PMID 36456987, PMID 38184642, PMID 39799376
1UG3AR085896 (1)