31 completed. 31 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 31 | Completed 31 |
Follow Foot Ulcer: new trials by email Literature Review of Foot Ulcer trials Research Report on Foot Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intraosseous Versus Intravenous Vancomycin in Below-Knee Amputation for Ischemic Diabetic Foot Intraosseous Vancomycin, Intravenous Vancomycin - Diabetic Foot Disease, Diabetic Foot Infection | Phase 4 | Completed | Başakşehir Çam & Sakura City Hospital | 40 | 2025-08-06 | 2026-07-10 |
| Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC) Amnion-Intermediate-Chorion, Standard of Care (SOC) - Diabetic Foot Ulcer | Phase 4 | Completed | Cellution Biologics | 84 | 2025-07-03 | 2026-08-20 |
| Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers Amnion-Intermediate-Chorion, Amnion-Chorion-Amnion, Standard of Care - Diabetic Foot Ulcer, Venous Leg Ulcer | Phase 4 | Completed | Cellution Biologics | 292 | 2024-10-14 | 2026-04-13 |
| Fitostimoline® Hydrogel Versus Saline Gauze Dressing in Diabetic Foot Ulcers Fitostimoline ® hydrogel group, Saline gauze group - Diabetic Foot | Phase 4 | Completed | Federico II University | 40 | 2021-02-01 | 2022-12-22 |
| The Effect of Treatment With Umbilical Cord Blood Platelet Lysate on Diabetic Foot Ulcers Umbilical cord blood platelel lysate gel - Diabetic Foot | Phase 4 | Completed | Attikon Hospital | 120 | 2019-06-10 | 2023-12-05 |
| GrafixPL PRIME Evaluation Case Study GrafixPL PRIME - Diabetic Foot Ulcer | Phase 4 | Completed | University of Texas Southwestern Medical Center | 40 | 2018-11-20 | 2023-07-24 |
| A Feasibility Study of the ReGenerCell™ Autologous Cell Harvesting Device for Diabetic Foot Ulcers ReGenerCell™ Autologous Cell Harvesting Device - Diabetic Foot Ulcer | Phase 4 | Completed | Avita Medical | 16 | 2016-05-01 | 2019-06-21 |
| GrafixPRIME® for the Treatment of Chronic Diabetic Foot Ulcers GrafixPRIME®, Dressing Application, Off-loading (walking boot) - Foot Ulcer, Diabetic | Phase 4 | Completed | Osiris Therapeutics | 75 | 2016-01-01 | 2017-07-17 |
| Use of Santyl in Diabetic Foot Ulcers Santyl, Product containing silver - Diabetic Foot, Foot Ulcer, Diabetic | Phase 4 | Completed | Smith & Nephew, Inc. | 102 | 2015-10-01 | 2018-08-01 |
| Evaluation of Woulgan in Diabetic Foot Ulcer Woulgan Gel, Intrasite Hydrogel - Diabetic Foot Ulcers | Phase 4 | Completed | Biotec Pharmacon ASA | 62 | 2015-10-01 | 2019-05-30 |
| GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds Grafix® - Complex Diabetic Foot Wounds | Phase 4 | Completed | Osiris Therapeutics | 31 | 2014-10-01 | 2016-02-02 |
| Santyl Applications to Diabetic Foot Ulcers Collagenase SANTYL® Ointment, Hydrogel (if needed) and foam dressing - Diabetic Foot Ulcers, Diabetic Foot Wounds | Phase 4 | Completed | Healthpoint | 215 | 2014-04-01 | 2016-02-17 |
| Skin Ulcers Treatment With an Handicraft Topical Device drenovac handcrafted, Healing - Foot Ulcer, Varicose Ulcer | Phase 4 | Completed | Coordinación de Investigación en Salud, Mexico | 144 | 2014-03-01 | 2015-07-30 |
| Efficacy and Safety of Garamycin® Sponge in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection Garamycin Sponge (Gentamicin-Collagen sponge), Systemic Antibiotic - Diabetic Foot Ulcer | Phase 4 | Completed | University Hospital, Geneva | 88 | 2013-09-01 | 2019-11-04 |
| LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers LeucoPatch, Usual care - Diabetic Foot Ulcer | Phase 4 | Completed | Nottingham University Hospitals NHS Trust | 269 | 2013-08-01 | 2018-06-25 |
| Study of Oasis Ultra in Diabetic Foot Ulcers Oasis, Standard - Diabetic Foot Ulcer | Phase 4 | Completed | Healthpoint | 82 | 2013-05-01 | 2015-01-22 |
| Grafix® DFU: Open-Label Extension Option to Evaluate Safety & Efficacy of Grafix® for Chronic Diabetic Foot Ulcers Tissue, Control - Diabetic Foot Ulcers | Phase 4 | Completed | Osiris Therapeutics | 97 | 2012-04-01 | 2014-04-09 |
| Using Santyl on Diabetic Foot Ulcers Santyl, Control - Diabetic Foot Ulcers, Diabetic Foot Wounds | Phase 4 | Completed | Healthpoint | 55 | 2011-08-01 | 2014-07-24 |
| DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 Diabetes Placebo, vildagliptin - Chronic Foot Ulcers | Phase 4 | Completed | University of Campania Luigi Vanvitelli | 106 | 2011-05-01 | 2016-10-11 |
| Wound Edge Changes Following Treatment With Santyl Collagenase Santyl Ointment, Placebo Comparator - Diabetic Foot Ulcers, Diabetic Foot Wounds | Phase 4 | Completed | Healthpoint | 10 | 2010-12-01 | 2013-05-30 |
Showing 20 of 31. Sign in to see all of them.
Diabetic Foot (27) · Diabetes Mellitus (5) · Varicose Ulcer (4) · Diabetes Mellitus, Type 2 (2) · Ulcer (2) · Diabetes Mellitus, Type 1 (1) · Diabetic Neuropathies (1) · Foot Injuries (1) · Ischemia (1) · Leg Ulcer (1) · Pressure Ulcer (1) · Wounds and Injuries (1)
Skin Diseases (31) · Skin Ulcer (31) · Skin and Connective Tissue Diseases (31) · Endocrine System Diseases (30) · Leg Ulcer (30) · Cardiovascular Diseases (27) · Diabetes Complications (27) · Diabetic Angiopathies (27) · Vascular Diseases (27) · Diabetic Neuropathies (26) · Diabetes Mellitus (25) · Glucose Metabolism Disorders (6) · Metabolic Diseases (6) · Nutritional and Metabolic Diseases (6)
Collagenases (5) · Standard of Care (4) · Histocompatibility Testing (2) · Hydrogels (1) · Petrolatum (1) · Piperacillin, Tazobactam Drug Combination (1) · Polydeoxyribonucleotides (1) · Saline Solution (1) · Vildagliptin (1) · cancer procoagulant (1)
Healthpoint (8) · Osiris Therapeutics (3) · Cellution Biologics (2) · Smith & Nephew, Inc. (2) · Attikon Hospital (1) · Avita Medical (1) · Başakşehir Çam & Sakura City Hospital (1) · Biotec Pharmacon ASA (1) · Coordinación de Investigación en Salud, Mexico (1) · Ethicon, Inc. (1) · Federico II University (1) · KCI USA, Inc (1) · Mrs. Thelma Zoegas Foundation (1) · Nottingham University Hospitals NHS Trust (1) · University Hospital, Geneva (1)
United States (17) · Sweden (4) · Italy (3) · United Kingdom (3) · Canada (2) · Denmark (2) · Germany (1) · Greece (1) · Switzerland (1) · Turkey (Türkiye) (1)
Herbert B Slade, MD (6) · Art J Tallis, DPM (1) · Carl Van Gils, DPM, CWS (1) · David Armstrong, DPM (1) · Davin Haraway, DO (1) · Fany Guadalupe Pat Espadas, MCs (1) · Frances Game, FRCP (1) · Giulia Cattarini (1) · Hebert B Slade, MD (1) · James Hart, MD (1) · Lawrence Lavery, DPM MPH (1) · Luis Sandoval Jurado, PhD (1)
PMID 16291063, PMID 17425550, PMID 20427683, PMID 20957342, PMID 23197976, PMID 24145042, PMID 25767565, PMID 27822727, PMID 30243803