8 completed, 3 active not recruiting, 2 recruiting, 2 withdrawn. 16 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 16 | Completed 8, Active not recruiting 3, Recruiting 2, Withdrawn 2, Unknown 1 |
| Phase 2 | 5 | Completed 2, Active not recruiting 1, Unknown 1, Withdrawn 1 |
Follow Fecal Incontinence: new trials by email Literature Review of Fecal Incontinence trials Research Report on Fecal Incontinence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| COPPER: A Trial Evaluating Copper-based Products for Incontinence-associated Dermatitis Diaper with a copper-based product + usual care, Barrier product with common diaper - Incontinence-associated Dermatitis | Phase 2 / Phase 3 | Withdrawn | Hospital Israelita Albert Einstein | 2025-09-01 | 2026-01-12 | |
| Mechanisms of Action on Rectal Motricity of Intrarectal Botulinum Toxin Injections intra-rectal botulinum toxin injections - Fecal Incontinence | Phase 3 | Recruiting | University Hospital, Rouen | 21 | 2025-04-15 | 2026-01-22 |
| Iltamiocel Compared to Placebo for Chronic Fecal Incontinence in Females With Obstetric Injury Iltamiocel, Placebo - Fecal Incontinence | Phase 3 | Active not recruiting | Cook MyoSite | 200 | 2024-03-21 | 2026-10-20 |
| The Safety and Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Fecal Incontinence Ramosetron, Psyllium - Fecal Incontinence | Phase 2 / Phase 3 | Active not recruiting | Seoul National University Hospital | 147 | 2024-01-19 | 2026-10-27 |
| Skeletal Muscle-derived Cell Implantation for Treatment of Fecal Incontinence aSMDC, Placebo - Fecal Incontinence | Phase 3 | Recruiting | Innovacell GmbH | 290 | 2022-05-11 | 2026-07-10 |
| Neostigmine and Glycopyrrolate by Iontophoresis Combination of Neostigmine and Glycopyrrolate, I-Box by Dynatronics - Spinal Cord Injuries, Constipation | Phase 3 | Active not recruiting | James J. Peters Veterans Affairs Medical Center | 6 | 2020-11-06 | 2024-04-08 |
| Bulking Agent Versus Electrostimulation Therapy in Anal Incontinence Bulking agent, Endoanal electrostimulation - Fecal Incontinence | Phase 2 / Phase 3 | Unknown | University of Sao Paulo | 60 | 2018-02-28 | 2018-02-06 |
| Effect and Tolerance of Botulinum A Toxin Rectal Injections on Fecal Incontinence Rectoscopy, Anorectal manometry, Botulinum toxin A or physiologic serum injection - Fecal Incontinence | Phase 3 | Completed | University Hospital, Rouen | 200 | 2015-11-25 | 2026-01-22 |
| A Study of Colesevelam in Fecal Incontinence Colesevelam, Clonidine, Placebo - Fecal Incontinence, Bile Acid Malabsorption | Phase 3 | Completed | Mayo Clinic | 88 | 2015-11-01 | 2023-06-22 |
| Controlling Anal Incontinence by Performing Anal Exercises With Biofeedback or Loperamide (CAPABLe) Loperamide, Placebo, Anal exercises with biofeedback - Fecal Incontinence | Phase 3 | Completed | NICHD Pelvic Floor Disorders Network | 300 | 2014-02-01 | 2018-11-20 |
| Comparison of PTNS and Biofeedback for Fecal Incontinence Posterior tibial nerve stimulation, Biofeedback - Fecal Incontinence | Phase 3 | Withdrawn | Seoul National University Hospital | 2014-01-01 | 2017-04-27 | |
| Autologous Myoblast Intrasphincteric Injection for Fecal Incontinence Myoblast injection, saline solution injection - Fecal Incontinence | Phase 2 / Phase 3 | Completed | University Hospital, Rouen | 24 | 2012-02-01 | 2015-10-23 |
| UK Trial of Percutaneous Tibial Nerve Stimulation in Patients With Faecal Incontinence Percutaneous Tibial Nerve Stimulation - Faecal Incontinence, Bowel Incontinence | Phase 3 | Completed | Queen Mary University of London | 227 | 2012-01-01 | 2015-01-28 |
| Percutaneous Tibial Nerve Stimulation in the Treatment of Fecal Incontinence Urgent PC neuromodulation system - Fecal Incontinence | Phase 3 | Completed | Maastricht University Medical Center | 59 | 2009-10-01 | 2015-08-26 |
| Efficacy and Mechanisms of Pharmacologic Treatment of Fecal Incontinence Psyllium powder, Loperamide - Fecal Incontinence | Phase 2 / Phase 3 | Completed | US Department of Veterans Affairs | 80 | 2008-07-01 | 2015-04-01 |
| Triple Target Treatment (3T) Which Combines Stimulation With Amplitude Modulated Middle Frequency (AM-MF), Electromyography (EMG)-Triggered Stimulation and EMG-Biofeedback Compared With EMG-Biofeedback in Anal Incontinence Combination of EMG-biofeedback plus EMG-triggered AM-MF-stimulation, EMG-biofeedback alone - Fecal Incontinence | Phase 3 | Completed | University of Giessen | 158 | 2007-07-01 | 2009-02-18 |
Encopresis (3) · Diarrhea (2) · Constipation (1) · Gastrointestinal Diseases (1) · Intestinal Diseases (1) · Neurogenic Bowel (1) · Rectal Diseases (1) · Spinal Cord Injuries (1) · Urinary Incontinence (1)
Digestive System Diseases (16) · Gastrointestinal Diseases (15) · Intestinal Diseases (15) · Rectal Diseases (15) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Signs and Symptoms, Digestive (5) · Behavior (3) · Behavioral Symptoms (3) · Elimination Disorders (3) · Mental Disorders (3) · Central Nervous System Diseases (1) · Colonic Diseases (1) · Colonic Diseases, Functional (1) · Female Urogenital Diseases (1)
Biofeedback, Psychology (2) · Loperamide (2) · Psyllium (2) · Botulinum Toxins, Type A (1) · Clonidine (1) · Colesevelam Hydrochloride (1) · Glycopyrrolate (1) · Iontophoresis (1) · Proctoscopy (1) · Saline Solution (1) · ramosetron (1)
University Hospital, Rouen (3) · Seoul National University Hospital (2) · Cook MyoSite (1) · Hospital Israelita Albert Einstein (1) · Innovacell GmbH (1) · James J. Peters Veterans Affairs Medical Center (1) · Maastricht University Medical Center (1) · Mayo Clinic (1) · NICHD Pelvic Floor Disorders Network (1) · Queen Mary University of London (1) · US Department of Veterans Affairs (1) · University of Giessen (1) · University of Sao Paulo (1)
France (5) · United States (5) · Germany (2) · Italy (2) · South Korea (2) · Austria (1) · Bulgaria (1) · Czechia (1) · Japan (1) · Netherlands (1) · Poland (1) · Slovenia (1) · Spain (1) · Sweden (1) · United Kingdom (1)
Adil Bharucha, MBBS, MD (1) · Alayne D Markland, DO MSc (1) · Christopher P Cardozo, MD (1) · Cornelius Baeten, prof phd md (1) · J E Jelovsek (1) · Matthew Barber (1) · Ron Jankowski, PhD (1) · Rumi Shin, MD, PhD (1) · Sung-Bum Kang, Ph.D. (1) · Thilo Schwandner, Dr. (1)
PMID 20551752, PMID 21968596, PMID 25565635, PMID 28703936, PMID 31320277, PMID 38128556
2014 (1), R01DK078924 (1), U01HD069031 (1), U10HD041261 (1), U10HD041267 (1), U10HD054214 (1), U10HD054215 (1), U10HD069006 (1), U10HD069010 (1), U10HD069013 (1), U10HD069025 (1), UL1RR024150 (1)