11 completed, 9 unknown, 6 not yet recruiting, 3 recruiting. 15 Not applicable, 5 Phase 3, 2 Phase 4, 1 Phase 2.
Follow Esotropia: new trials by email Literature Review of Esotropia trials Research Report on Esotropia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomized Trial of Botulinum Toxin A vs Strabismus Surgery for Esotropia >10 to ≤30PD Botulinum toxin A, bilateral medial rectus recession - Esotropia | Phase 3 | Not yet recruiting | Jaeb Center for Health Research | 244 | 2027-01-01 | 2026-04-06 |
| Visual Therapy for Intermittent Strabismus Visual Therapy - Intermittent Strabismus, Exotropia Intermittent | Not applicable | Not yet recruiting | Universitat Politècnica de Catalunya | 30 | 2026-05-01 | 2026-05-04 |
| Risk Factors And Surgical Outcomes Of Strabismus Reoperation Horizontal Strabismus Reoperation - Strabismus, Esotropia | Not applicable | Not yet recruiting | Assiut University | 62 | 2026-03-01 | 2026-03-09 |
| Botulinum Toxin for Strabismus Treatment Botox injection into extraocular muscles - Strabismic Deviation, Strabismus | Not applicable | Not yet recruiting | Foundation University Islamabad | 127 | 2025-09-30 | 2025-09-18 |
| Bifocal Spectacles vs. Single Vision Spectacles for Esotropia Greater at Near Bifocal Spectacles, Single Vision Lenses - Esotropia | Phase 3 | Withdrawn | Jaeb Center for Health Research | 2025-09-01 | 2025-05-31 | |
| Prism Adaptation in Symptomatic Esophoria - Effect of Shorter Time Intervals and Surgical Outcomes Based on Prism Adaptation Prism adaptation test, other - Esophoria | Not applicable | Recruiting | Copenhagen University Hospital, Rigshospitalet | 100 | 2025-05-19 | 2025-07-22 |
| Accommodation-Related Visual Training Combined with Transcranial Electrical Stimulation Versus Visual Training Alone for the Treatment of Accommodation Dysfunction Transcranial Electrical Stimulation, Visual Training - Presbyopia, Esotropia | Not applicable | Not yet recruiting | Eye & ENT Hospital of Fudan University | 100 | 2024-12-31 | 2024-12-05 |
| Botulinum Toxin Injection Versus Prism Treatment in Small-angle Acute Acquired Concomitant Esotropia prism treatment group, botulinum toxin group - Esotropia | Not applicable | Not yet recruiting | Eye & ENT Hospital of Fudan University | 100 | 2024-12-10 | 2024-12-05 |
| Vision Therapy Versus Prism Treatment in Small-angle Acute Acquired Concomitant Esotropia Vision therapy group, Prism - Esotropia | Not applicable | Recruiting | Eye & ENT Hospital of Fudan University | 100 | 2024-09-07 | 2026-09-04 |
| Medial Rectus Fenestration vs Recession for PAET medial rectus fenestration, medial rectus recession - Partially Accommodative Esotropia | Not applicable | Unknown | Mansoura University | 60 | 2023-11-15 | 2024-03-07 |
| Performance and Safety Evaluation of the S360 Medical Device Software. S360 - Binocular Vision Disorder, Binocular Eye Movement Disorder | Not applicable | Unknown | Sierra Neurovision | 200 | 2023-11-02 | 2023-04-19 |
| Cycloplegic Refraction in Pediatric Patients With Esotropia Cyclopentolate, Tropicamide - Cycloplegia, Refractive Errors | Phase 4 | Unknown | Islamic Hospital, Jordan | 100 | 2023-09-01 | 2023-10-11 |
| Validation of a Smartphone-based Intelligent Diagnosis and Measurement for Strabismus A new technology based on 3D reconstruction and deep learning algorithm to achieve an automatic diagnosis of strabismus based on patient-sourced videos of programmatic cover tests. - Strabismus, Exotropia | Unknown | Sun Yat-sen University | 300 | 2022-12-02 | 2022-12-05 | |
| Genetic Studies of Strabismus, Nystagmus, and Associated Disorders whole genome sequencing or whole exome sequencing - Strabismus, Nystagmus, Congenital | Recruiting | Boston Children's Hospital | 400 | 2021-09-03 | 2025-12-12 | |
| Characteristics of the Vergence Responses of Binocularly Normal Subjects After a Vision Therapy Protocol Experimental: Classical Vision Therapy Treatment, Control: Eye Movement Therapy Treatment - Vision Disorders, Eye; Movement Disorder (Binocular) | Not applicable | Unknown | Universitat Politècnica de Catalunya | 34 | 2021-09-02 | 2022-01-26 |
| Changes in Refractive Error in Patients With Both Partially Refractive Esotropia and Amblyopia Refractive Errors, Esotropia | Completed | Sakarya University | 58 | 2019-01-02 | 2020-06-12 | |
| Efficacy of Botulinum Toxin Type A for Acute Acquired Comitant Esotropia: An Age-Stratified Two-Year Follow-Up Study Botulinum Toxin Type A Injection [Botox] - Acute Acquired Comitant Esotropia | Not applicable | Completed | Second Affiliated Hospital, Zhejiang University, School of Medicine | 276 | 2019-01-01 | 2025-05-13 |
| Strabismus Surgery and Driving Ability Strabismus, Esotropia | Completed | University Hospital, Strasbourg, France | 40 | 2013-11-01 | 2019-08-20 | |
| Binocular Treatment of Amblyopia Before and After Strabismus Surgery Binocular Treatment, Sham Binocular Treatment - Amblyopia, Strabismus | Not applicable | Completed | Massachusetts Eye and Ear Infirmary | 22 | 2013-01-01 | 2017-01-13 |
| Bupivacaine Injection of Eye Muscles to Treat Strabismus Bupivacaine - Strabismus, Esotropia | Phase 2 / Phase 3 | Unknown | Smith-Kettlewell Eye Research Institute | 120 | 2012-04-01 | 2019-09-23 |
Showing 20 of 30. Sign in to see all of them.
Strabismus (12) · Exotropia (8) · Amblyopia (2) · Blepharoptosis (2) · Myopia (2) · Refractive Errors (2) · Vision Disorders (2) · Diplopia (1) · Graves Disease (1) · Hyperopia (1) · Nystagmus, Congenital (1) · Nystagmus, Pathologic (1) · Presbyopia (1)
Cranial Nerve Diseases (30) · Eye Diseases (30) · Nervous System Diseases (30) · Ocular Motility Disorders (30) · Strabismus (18) · Neurologic Manifestations (5) · Pathological Conditions, Signs and Symptoms (5) · Sensation Disorders (5) · Signs and Symptoms (5) · Refractive Errors (4) · Vision Disorders (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Eyelid Diseases (2) · Autoimmune Diseases (1)
Botulinum Toxins, Type A (3) · Bupivacaine (1) · Contact Lenses, Hydrophilic (1) · Cyclopentolate (1) · Exome Sequencing (1) · Eyeglasses (1) · PRDM6, protein, mouse (1) · Saline Solution (1) · Sodium Chloride (1) · Transcranial Direct Current Stimulation (1) · Tropicamide (1) · Whole Genome Sequencing (1)
Eye & ENT Hospital of Fudan University (3) · National Eye Institute (NEI) (3) · Jaeb Center for Health Research (2) · Universitat Politècnica de Catalunya (2) · Aller, Thomas A., OD (1) · Assiut University (1) · Boston Children's Hospital (1) · Copenhagen University Hospital, Rigshospitalet (1) · Erasmus Medical Center (1) · Foundation University Islamabad (1) · Hospital Universitario Ramon y Cajal (1) · Islamic Hospital, Jordan (1) · Mansoura University (1) · Massachusetts Eye and Ear Infirmary (1) · National Centre of Ophthalmology named after academician Zarifa Aliyeva (1)
China (5) · United States (3) · Egypt (2) · France (2) · Spain (2) · Brazil (1) · Canada (1) · Denmark (1) · Germany (1) · Jordan (1) · Netherlands (1) · Pakistan (1) · Qatar (1) · Taiwan (1) · Turkey (Türkiye) (1)
Wen Wen, MD, PhD (2) · Agnes Wong, MD (1) · Alan B Scott, MD (1) · Ameera G Abdelhameed, MD (1) · Arnaud Sauer, MDPHD (1) · Burcin Cakir, MD (1) · Dean Cestari, M.D. (1) · Dr. Sana Nadeem Assoc. Prof., FCPS (1) · Elmar Kasimov, Professor (1) · Huib J. Simonsz, MD, PhD (1) · Jaime Tejedor, MD, PhD (1) · Joel M Miller, PhD (1) · Mary Whitman, MD/PhD (1) · Michael X Repka, MD, MBA (1) · Nilza Minguini, MD, PhD (1)
PMID 36809645, PMID 15642806, PMID 16044063, PMID 18852411, PMID 20126486, PMID 21057347, PMID 21209494, PMID 21870914, PMID 25309358, PMID 29577409, PMID 30570596, PMID 31640452, PMID 32800454, PMID 34516656, PMID 36680614, PMID 39773345, PMID 42828678
R01EY032539 (1), U10EY011751 (1), UG1EY011751 (1)