17 completed, 16 recruiting, 5 unknown, 4 active not recruiting. 21 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 9, Recruiting 7, Not yet recruiting 2, Active not recruiting 1, Enrolling by invitation 1, Withdrawn 1 |
Follow Whole Genome Sequencing: new trials by email Literature Review of Whole Genome Sequencing trials Research Report on Whole Genome Sequencing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MicroRNAs as Biomarkers in First Episode Schizophrenia Plasma NDE miRNA Sequencing, Whole Genome Sequencing - Schizophrenia Disorder, Schizophreniform Disorder | Not applicable | Recruiting | Northwell Health | 160 | 2026-07-01 | 2026-07-14 |
| Diabetes In Asians at Risk in Youth Oral glucose tolerance test and HbA1c, Anthropometric measurements, Body impedance Analysis - Young Onset Asian Diabetes (Under 40 Years) | Not yet recruiting | Singapore General Hospital | 3000 | 2026-03-18 | 2026-03-05 | |
| Environmental Reservoirs of Non-tuberculous Mycobacteria in Cystic Fibrosis Households Multi-modal NTM diagnostic including PCR, WGS, culture - Cystic Fibrosis (CF), Mucoviscidosis | Recruiting | Research Center Borstel | 120 | 2026-02-16 | 2026-08-19 | |
| Associations Between Dental Anomalies and Ocular, Cutaneous and Skin Appendages Features Whole Genome Sequencing, Cephalometric tracing - Congenital Cataract, Tooth Abnormalities | Not applicable | Not yet recruiting | University of Pavia | 5 | 2026-02-01 | 2025-11-19 |
| The NorCUP Trial: Improving Prognosis and Personalized Treatment in Cancer of Unknown Primary (CUP) Comprehensive molecular profiling - Cancer of Unknown Primary Site | Not applicable | Not yet recruiting | Haukeland University Hospital | 350 | 2026-01-01 | 2026-01-26 |
| "A Privacy-protecting Environment for Child Transplants Health Related and Genomic Data Integration in the European Reference Network" Whole genome sequencing, Polygenic Risk Score Calculation, Methylome and episignatures - Transplant Complication, Kidney Transplant | Not yet recruiting | Instituto de Investigación Hospital Universitario La Paz | 200 | 2025-09-30 | 2025-09-26 | |
| National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry whole genome sequencing - Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated | Recruiting | Hospital do Coracao | 1211 | 2025-04-30 | 2026-05-08 | |
| Post-Transplant Diabetes Outcomes Prediction Whole genome sequencing (WGS) - New Onset Diabetes After Transplantation | Not applicable | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 120 | 2024-08-31 | 2026-04-06 |
| Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome whole genome sequencing - Sudden Infant Death, Sudden Unexplained Infant Death | Recruiting | Nantes University Hospital | 650 | 2024-08-27 | 2026-06-18 | |
| Integrating Whole Genome Sequencing and Digital Twins Into the Management of Hypercholesterolemia in Emiratis Whole Genome Sequencing - Hypercholesterolemia, Autosomal Dominant, Hypercholesterolemia, Autosomal Recessive | Not applicable | Recruiting | Abu Dhabi Health Services Company | 40 | 2024-07-29 | 2025-03-25 |
| Expanding NGS Data with Optical Genome Mapping (OGM) Optical Genome Mapping (OGM) and Whole Genome Sequencing (WGS), Trascriptome analysis - Neurodevelopmental Disorder (Diagnosis) | Not applicable | Recruiting | IRCCS Eugenio Medea | 60 | 2024-05-23 | 2025-02-28 |
| Whole Genome Sequencing Versus Whole Exome Sequencing for Congenital Diarrhea and Enteropahty Whole genome sequencing, Whole exome sequencing - Diarrhea, Infantile, Enteropathy | Not applicable | Recruiting | Children's Hospital of Fudan University | 180 | 2024-05-01 | 2026-03-24 |
| Baker Gordon Syndrome Natural History Study Brain Magnetic Resonance Imaging (MRI), Whole Genome Sequencing, Induced Pluripotential Stem Cells - Rare Diseases, Autism or Autistic Traits | Recruiting | University of Missouri-Columbia | 50 | 2024-04-30 | 2026-06-03 | |
| Implementing a National Biobank of PD With WGS and Functional Assessment of Polygenic Inheritance by iPSC Technology whole genome sequencing - Parkinson Disease, REM Sleep Behavior Disorder | Recruiting | IRCCS San Raffaele | 230 | 2023-10-30 | 2026-03-30 | |
| NeuralNET Cerebral Palsy Pilot Study Whole-genome sequencing - Cerebral Palsy | Active not recruiting | University of Cambridge | 66 | 2023-04-14 | 2025-03-30 | |
| Newborn Genomic Sequencing Pilot Study Whole genome sequencing, BeginNGS test, WES - Genetic Disease | Not applicable | Completed | Rady Pediatric Genomics & Systems Medicine Institute | 120 | 2023-03-13 | 2024-11-14 |
| Predictive Biomarkers of Response to Checkpoint Inhibitors in Triple Negative Breast Cancer: a Multiomics Platform Whole Genome Sequencing, RNA-Sequencing, Microbiome analysis - Triple Negative Breast Cancer | Recruiting | Vall d'Hebron Institute of Oncology | 100 | 2023-01-13 | 2023-06-23 | |
| Precision Medicine for Every Child With Cancer Whole Genome Sequencing, RNA seq, DNA Methylation - Childhood Cancer, Childhood Solid Tumor | Recruiting | Australian & New Zealand Children's Haematology/Oncology Group | 3500 | 2022-12-16 | 2024-07-17 | |
| Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models whole genome sequencing - Inherited Retinal Dystrophy, Retinitis Pigmentosa | Completed | Istituto Superiore di Sanità | 120 | 2022-11-15 | 2025-04-18 | |
| Glioblastoma Targeted Treatment Option Maximization by WGS whole genome sequencing - Glioblastoma | Not applicable | Completed | UMC Utrecht | 164 | 2022-07-25 | 2026-06-04 |
Showing 20 of 49. Sign in to see all of them.
Genetic Diseases, Inborn (6) · Rare Diseases (4) · Cardiomyopathy, Dilated (3) · Disease (3) · Intellectual Disability (3) · Cardiomyopathy, Hypertrophic (2) · Congenital Abnormalities (2) · Cystic Fibrosis (2) · Diabetes Mellitus, Type 2 (2) · Genetic Predisposition to Disease (2) · Hyperlipoproteinemia Type II (2) · Neoplasms (2) · Abnormalities, Multiple (1) · Arrhythmogenic Right Ventricular Dysplasia (1) · Autistic Disorder (1)
Institut National de la Santé Et de la Recherche Médicale, France (2) · Nantes University Hospital (2) · Abu Dhabi Health Services Company (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Australian & New Zealand Children's Haematology/Oncology Group (1) · Blood Donation Service Zurich, SRC (1) · Boston Children's Hospital (1) · Brigham and Women's Hospital (1) · Carmel Medical Center (1) · Charite University, Berlin, Germany (1) · Children's Hospital of Fudan University (1) · Children's Mercy Hospital Kansas City (1) · Children's Oncology Group (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Haukeland University Hospital (1)
United States (12) · Italy (6) · France (4) · United Kingdom (4) · China (3) · Germany (3) · Netherlands (2) · Spain (2) · Australia (1) · Belgium (1) · Brazil (1) · Canada (1) · Denmark (1) · Egypt (1) · Finland (1)
Abdel-Aziz Zidan, lecturer (1) · Abdulmajeed BS Alzubaidi, MD (1) · Alexander Mischnik, Prof. Dr. med. (1) · Andrea Scribante (1) · Asem Elfert, Prof (1) · Ayman Elsaka, prof (1) · Benjamin Wilfond, MD (1) · Christoph Gassner, PhD (1) · Clara DM van Karnebeek, Professor (1) · Daphne SL Gardner, BA, BMBCh(Oxon), MRCP (UK) (1) · David Rowitch, MD (1) · David Ziegler (1) · Elena Elimova (1) · Elias Kumbakumba, MD (1)
PMID 24645908, PMID 25612602, PMID 28654958, PMID 29030401, PMID 33146628, PMID 35383076, PMID 36029725, PMID 36291375, PMID 36333718, PMID 37207655, PMID 38423010, PMID 38466850, PMID 39228063, PMID 40121439, PMID 40738637, PMID 40885189, PMID 41044778, PMID 42624826, PMID 42830293
1UM1HG007292-01 (1), R01EY032539 (1), R01HD107190 (1), U01HG006500 (1)