18 completed, 4 unknown, 1 terminated. 12 Phase 4, 4 Phase 3, 3 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 8, Unknown 4 |
| Phase 3 | 4 | Completed 4 |
| Not applicable | 3 | Completed 2, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Tropicamide: new trials by email Literature Review of Tropicamide trials Research Report on Tropicamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of 4 Methods of Eye Drops for Pupil Dilation in Diabetic Patients 1 drop of a 0.8% tropicamide + 5% phenylephrine combination, 1 drop of 0.5% tetracaine and 1 drop of a 0.8% tropicamide + 5% phenylephrine combination, 3 drops of a 0.8% tropicamide + 5% phenylephrine combination - Diabetes (DM), Retinopathy, Diabetic | Not applicable | Completed | Burapha University | 84 | 2024-11-04 | 2026-03-27 |
| Safety and Efficacy of Fixed Combination Phenylephrine-Tropicamide for Pupil Dilation MydCombi - Mydriasis | Phase 4 | Completed | Eyenovia Inc. | 30 | 2023-11-28 | 2024-04-18 |
| Cycloplegic Refraction in Pediatric Patients With Esotropia Cyclopentolate, Tropicamide - Cycloplegia, Refractive Errors | Phase 4 | Unknown | Islamic Hospital, Jordan | 100 | 2023-09-01 | 2023-10-11 |
| Wearing-Off Period of Pharmacological Dilation and Anisocoria Tropicamide, 1% Pilocarpine, Proparacaine Hydrochloride - Anisocoria | Phase 4 | Completed | Prisma Health-Upstate | 11 | 2022-04-01 | 2023-03-07 |
| Cycloplegic Refraction Among Children Cyclopentolate, Tropicamide - Cycloplegia | Phase 4 | Completed | Islamic Hospital, Jordan | 55 | 2022-03-01 | 2022-07-05 |
| Comparison Mydriasis by Mydrane With Topical Drop Application Eye injection (Mydrane), eye drops (Phenylephrin), eye drops (Tropicamid) - Cataract | Phase 4 | Completed | Medical University of Graz | 42 | 2020-08-12 | 2021-10-19 |
| Efficacy and Safety of Mydriatic Microdrops Compared With Standard Drops for Retinopathy of Prematurity (ROP) Screening: a Pilot Randomized Clinical Trial Microdrop administration [phenylephrine 1.67% + tropicamide 0.33% (drop volume: 6-7 μL)], Standard drop administration [phenylephrine 1.67% + tropicamide 0.33% (drop volume: 28-34 μL)] - Retinopathy of Prematurity | Phase 4 | Completed | Aristotle University Of Thessaloniki | 25 | 2020-03-24 | 2022-04-04 |
| Performance of Rigid Gas Permeable (RGP) Scleral Contact Lenses With a Passive Artificial Iris Scleral contact lens without a passive artificial iris, Scleral contact lens with a passive artificial iris with low contrast (<1:5), Scleral contact lens with a passive artificial iris with high contrast (>1:5) - Low Vision | Not applicable | Terminated | University Ghent | 10 | 2019-09-16 | 2022-04-27 |
| The Effect of Brimonidine Brimonidine, Tropicamide, Phenylephrine Ophthalmic Product - Intraocular Pressure | Phase 4 | Completed | Wake Forest University Health Sciences | 13 | 2019-07-20 | 2024-02-01 |
| Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation Tropicamide/Phenylephrine ophthalmic solution (TR/PE), Placebo - Mydriasis | Phase 3 | Completed | Eyenovia Inc. | 76 | 2018-12-01 | 2022-03-18 |
| Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation Tropicamide 1%-Phenylephrine 2.5% ophthalmic solution (TR/PE), Tropicamide 1% ophthalmic solution (TR), Phenylephrine 2.5% ophthalmic solution (PE) - Mydriasis | Phase 3 | Completed | Eyenovia Inc. | 70 | 2018-11-15 | 2022-03-18 |
| The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients Alphagan, Phenylephrine, Tropicamide - Intraocular Pressure | Phase 1 | Completed | Wake Forest University Health Sciences | 5 | 2016-09-01 | 2018-08-09 |
| Efficacy of Mydriatic Drops in Premature Infants Drug used in the examination of premature infants. - Retinopathy of Prematurity | Completed | Bulent Ecevit University | 60 | 2016-01-15 | 2018-02-28 | |
| Descemet Endothelial Thickness Comparison Trial DSAEK, DMEK, Endoserter - Keratoplasty, Grafting, Corneal | Phase 4 | Unknown | Oregon Health and Science University | 38 | 2015-01-22 | 2020-11-25 |
| Clinical Investigation on the Blood Oxygenation at the Optic Nerve Head in Fabry Patients Contrast sensitivity measurement, Slit Lamp assessment and intra-ocular pressure measurement, Visual field testing - Fabry Disease | Completed | Université de Montréal | 8 | 2014-08-01 | 2024-09-19 | |
| Subfoveal Choroidal Thickness After Surgery for Age-related Cataracts Femtosecond laser-assisted cataract surgery, Conventional phacoemulsification cataract surgery, Tropicamide - Cataract | Not applicable | Completed | Sun Yat-sen University | 40 | 2014-08-01 | 2016-09-09 |
| A New More Efficient Cycloplegia Scheme Cyclopentolate, Cyclopentolate+tropicamide+phenylephrine - Refractive Errors | Phase 4 | Unknown | Pontificia Universidad Catolica de Chile | 30 | 2014-05-01 | 2014-06-27 |
| Changes in Vital Signs and Pupil Diameter Related to Pharmacologic Mydriasis in Premature Infants: A Randomized Double Blind Clinical Study 0.5% cyclopentolate and 2.5% phenylephrine, 0.5% tropicamide + 0.5% phenylephrine, 0.5% tropicamide + 0.5% phenylephrine with a cotton wick - Retinopathy of Prematurity | Phase 4 | Completed | University of the Philippines | 60 | 2011-09-30 | 2021-04-09 |
| Efficacy and Safety Assessment of Intracameral Injection of T2380 in Cataract Surgery T2380, Mydriatics, Tetracaine - Cataract | Phase 3 | Completed | Laboratoires Thea | 609 | 2011-06-01 | 2014-11-14 |
| Comparison of Instillation and Packing in Mydriasis for Premature Infants 1% tropicamide and 2.5% phenylephrine - Preterm Infants | Phase 4 | Completed | Khon Kaen University | 25 | 2009-03-01 | 2012-03-09 |
Showing 20 of 23. Sign in to see all of them.
Mydriasis (8) · Cataract (3) · Refractive Errors (3) · Retinopathy of Prematurity (3) · Anisocoria (1) · Corneal Diseases (1) · Diabetes Mellitus (1) · Diabetic Retinopathy (1) · Dilatation, Pathologic (1) · Esotropia (1) · Eye Diseases (1) · Fabry Disease (1) · Myopia (1) · Parkinson Disease (1) · Sialorrhea (1)
Eyenovia Inc. (3) · Islamic Hospital, Jordan (2) · Khon Kaen University (2) · Wake Forest University Health Sciences (2) · Aristotle University Of Thessaloniki (1) · Bulent Ecevit University (1) · Burapha University (1) · Laboratoires Thea (1) · Medical University of Graz (1) · Min-Sheng General Hospital (1) · NeuroHealing Pharmaceuticals Inc. (1) · Oregon Health and Science University (1) · Pontificia Universidad Catolica de Chile (1) · Prisma Health-Upstate (1) · Sun Yat-sen University (1)
United States (7) · Thailand (3) · Jordan (2) · Argentina (1) · Austria (1) · Belgium (1) · Canada (1) · Chile (1) · China (1) · France (1) · Greece (1) · Qatar (1) · Taiwan (1)
Keith Walter, MD (2) · Tsontcho Ianchulev, MD, MPH (2) · Yosanan Yospaiboon, M.D. (2) · Andres F Vasquez Quintero, Professor (1) · Charles Lin, MD (1) · Cristian Salgado (1) · Elkan R Gamzu, PhD (1) · Greg Bennett, MS (1) · Haotian Lin, M.D., Ph.D (1) · Jennifer Rose-Nussbaumer, MD (1) · Langis Michaud, OD M.Sc. (1) · Leon Chih-Kai Liang, MD MMS (1) · Marcelo Merello, MD, PhD (1)
PMID 10714690, PMID 15097885, PMID 15226730, PMID 15240989, PMID 17205877, PMID 20835704, PMID 21636098, PMID 22123352, PMID 22368443, PMID 25449644, PMID 26531052, PMID 27159349, PMID 27519933, PMID 29945801, PMID 31046075, PMID 31690284, PMID 32126990, PMID 34654903, PMID 6546977, PMID 7267230, PMID 8695564, PMID 8823596, PMID 9458936