3 completed, 3 recruiting, 2 not yet recruiting. 8 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 3, Recruiting 3, Not yet recruiting 2 |
Follow Endocarditis: new trials by email Literature Review of Endocarditis trials Research Report on Endocarditis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dalbavancin Therapy for Infective Endocarditis Dalbavancin administration, Standard of Care (Investigator Choice) - Endocarditis Infective, Endocarditis, Bacterial | Phase 3 | Not yet recruiting | Stefan Hagel | 184 | 2026-12-01 | 2026-07-13 |
| A Study of Ceftobiprole Compared With Standard Antibiotic Treatment in Children With Staphylococcus Aureus Bacteremia (SAB) Infection, Including Right-sided Heart Infection Ceftobiprole medocaril sodium, Standard of Care (SOC) - Staphylococcus Aureus Bacteremia, Endocarditis, Bacterial | Phase 3 | Not yet recruiting | ISTx, LLC | 60 | 2026-10-30 | 2026-11-10 |
| Rifampin-free Regimen Versus Rifampin-containing Regimen in the Treatment of Staphylococcal Prosthetic Valve Endocarditis Rifampin-free regimen, Rifampin containing regimen - Infective Endocarditis | Phase 3 | Recruiting | Nantes University Hospital | 422 | 2026-06-11 | 2026-10-21 |
| Bacteriophages in Addition to Antibiotics for the Treatment of Patients With Infective Endocarditis Bacteriophage - Endocarditis, Bacterial | Phase 3 | Recruiting | University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba) | 30 | 2025-02-05 | 2026-03-19 |
| New Treatment of Cardiac Device Infections; Immediate Reimplantation After Removal of Infected System Timing of reimplantation - Endocarditis, Bacterial | Phase 3 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 176 | 2024-04-29 | 2026-10-01 |
| Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Streptococcus Amoxicillin, Conventional IV treatment of streptococci/enterococci IE following European guidelines 2015 including amoxicillin, gentamicin, amicillin, vancomycin, penicillin G, ceftriaxone, netilmicin - Infective Endocarditis | Phase 3 | Completed | University Hospital, Tours | 324 | 2016-02-29 | 2026-02-12 |
| Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Staphylococcus Levofloxacin, Rifampicin, Conventional IV treatment of staphylococci IE following European guidelines 2015 including cloxacilline, oxacilline,gentamicine,vancomycine,rifampicine - Infective Endocarditis | Phase 3 | Completed | University Hospital, Tours | 162 | 2016-02-29 | 2026-02-12 |
| Daptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. Aureus daptomycin - Bacterial Endocarditis, Bacteremia | Phase 3 | Completed | Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2002-03-01 | 2017-02-13 |
Endocarditis, Bacterial (5) · Staphylococcal Infections (2) · Bacteremia (1) · Gram-Positive Bacterial Infections (1)
Cardiovascular Diseases (8) · Heart Diseases (8) · Bacterial Infections (6) · Bacterial Infections and Mycoses (6) · Infections (6) · Cardiovascular Infections (5) · Gram-Positive Bacterial Infections (1) · Inflammation (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1) · Sepsis (1) · Systemic Inflammatory Response Syndrome (1)
Standard of Care (2) · Amoxicillin (1) · Ceftriaxone (1) · Daptomycin (1) · Fluoroquinolones (1) · Gentamicins (1) · Levofloxacin (1) · Netilmicin (1) · Oxacillin (1) · Penicillin G (1) · Rifampin (1) · Vancomycin (1) · ceftobiprole medocaril (1)
University Hospital, Tours (2) · Copenhagen University Hospital, Rigshospitalet (1) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · ISTx, LLC (1) · Nantes University Hospital (1) · Stefan Hagel (1) · University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba) (1)
France (3) · Denmark (1) · Germany (1) · Russia (1)
Henning Henning (1)