6 completed, 2 terminated, 1 no longer available, 1 recruiting. 5 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Terminated 1 |
| Phase 2 | 5 | Completed 2, Recruiting 1, Terminated 1, Unknown 1 |
Follow West Nile Fever: new trials by email Literature Review of West Nile Fever trials Research Report on West Nile Fever
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High-Titer Neutralizing Plasma for West Nile Fever in Hospitalized Patients Plasma - West Nile Fever | Phase 2 | Recruiting | Gili Regev-Yochay MD | 37 | 2025-07-30 | 2025-08-26 |
| Early Interferon-beta Treatment for West-Nile Virus Infection Rebif 44 MCG Per 0.5 ML Prefilled Syringe, Saline - West Nile Virus, West Nile Fever Encephalitis | Phase 2 | Unknown | Tel-Aviv Sourasky Medical Center | 100 | 2024-07-14 | 2024-07-23 |
| Prospective Investigation of Oxidative Stress in West Nile Virus Infection West Nile Virus, West Nile Fever | Withdrawn | Institute of Tropical Medicine, Belgium | 2020-09-01 | 2021-02-10 | ||
| Treatment of West Nile Virus With MGAWN1 MGAWN1, Placebo - normal saline - West Nile Neuroinvasive Disease, West Nile Virus Infection | Phase 2 | Terminated | MacroGenics | 13 | 2009-05-01 | 2022-02-10 |
| Safety and Immunogenicity Study of ChimeriVax West Nile Vaccine in Healthy Adults ChimeriVax-WN02 vaccine, Placebo - West Nile Fever | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 479 | 2008-10-01 | 2015-04-03 |
| Safety of and Immune Response to a West Nile Virus Vaccine (WN/DEN4delta30) in Healthy Adults WN/DEN4delta30 vaccine, Placebo - West Nile Fever | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 26 | 2008-03-01 | 2013-01-03 |
| Phase I Study of West Nile Virus Vaccine VRC-WNVDNA020-00-VP - West Nile Fever | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 30 | 2006-03-03 | 2017-07-02 |
| Safety and Immunogenicity of ChimeriVax-WN02 West Nile Vaccine in Healthy Adults ChimeriVax-WN02 Low Dose, ChimeriVax-WN02 Medium Dose, ChimeriVax-WN02 High Dose - West Nile Fever | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 208 | 2005-12-01 | 2016-04-14 |
| Vaccine to Prevent West Nile Virus Disease VRC-WNVDNA017-00-VP - Healthy, West Nile Fever | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 15 | 2005-03-22 | 2017-07-02 |
| Safety of and Immune Response to a West Nile Virus Vaccine (WN/DEN4-3'delta30) in Healthy Adults WN/DEN4-3'delta30, Placebo - West Nile Fever Encephalitis | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 56 | 2005-02-01 | 2013-01-03 |
| An Exploratory Study of AVI-4020 in Patients With Possible Acute Neuroinvasive West Nile Virus (WNV) Disease AVI-4020 Injection - West Nile Fever | Phase 1 | Terminated | Sarepta Therapeutics, Inc. | 50 | 2004-11-01 | 2009-07-08 |
| Expanded Access to MGAWN1 in Subjects With Suspected West Nile Neuroinvasive Disease; Suspected West Nile Virus Infection; or Substantial Accidental Exposure MGAWN1 - West Nile Virus Infection | No longer available | MacroGenics | 2022-02-22 |
Encephalitis (3) · Meningitis (2) · acute flaccid myelitis (2) · Viremia (1) · Virus Diseases (1)
Arbovirus Infections (12) · Brain Diseases (12) · Central Nervous System Diseases (12) · Central Nervous System Infections (12) · Central Nervous System Viral Diseases (12) · Encephalitis, Arbovirus (12) · Encephalitis, Viral (12) · Flaviviridae Infections (12) · Flavivirus Infections (12) · Infections (12) · Infectious Encephalitis (12) · Mosquito-Borne Diseases (12) · Nervous System Diseases (12) · Neuroinflammatory Diseases (12) · RNA Virus Infections (12)
Interferon beta-1a (1) · Saline Solution (1) · Sodium Chloride (1)
National Institute of Allergy and Infectious Diseases (NIAID) (4) · MacroGenics (2) · Sanofi Pasteur, a Sanofi Company (2) · Gili Regev-Yochay MD (1) · Institute of Tropical Medicine, Belgium (1) · Sarepta Therapeutics, Inc. (1) · Tel-Aviv Sourasky Medical Center (1)
United States (6) · Israel (2) · Romania (1)
Anna Durbin, M.D. (1) · Anna Durbin, MD (1) · Corneliu Popescu (1) · Gili Regev-Yochay, MD (1) · Koen Vercauteren (1) · Nina Hermans (1)
PMID 15714427, PMID 18190252, PMID 21148499, PMID 21398392, PMID 33763778, PMID 36780676