36 completed, 10 recruiting, 10 unknown, 4 not yet recruiting. 65 Phase 2, 5 Phase 1, 5 Phase 3.
Follow Encephalitis: new trials by email Literature Review of Encephalitis trials Research Report on Encephalitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Pharmacokinetics and Efficacy of BV100 Plus Low Dose Polymyxin B Plus Ceftazidime/Avibactam, or Plus Cefiderocol in Patients With Pulmonary and Extrapulmonary Infections Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex BV100 with 50 mg polymyxin B plus ceftazidime/avibactam, BV100 with 50 mg polymyxin B plus cefiderocol, Best Available Therapy (BAT) - Ventilator Associated Bacterial Pneumonia (VABP), Hospital Acquired Bacterial Pneumonia (HABP) | Phase 2 | Not yet recruiting | BioVersys AG | 120 | 2026-07-01 | 2026-02-24 |
| Efgartigimod in Anti-NMDA Receptor Encephalitis. Efgartigimod Alfa - Encephalitis Autoimmune | Phase 2 | Recruiting | Beijing Tongren Hospital | 20 | 2026-06-25 | 2026-09-16 |
| Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study Brincidofovir - Progressive Multifocal Leukoencephalopathy | Phase 2 | Recruiting | National Institute of Neurological Disorders and Stroke (NINDS) | 24 | 2026-06-05 | 2026-07-22 |
| A Study in Participants With Anti-NMDAR Encephalitis and Anti-NMDAR Autoantibody-Associated Psychiatric Disease ART5803, ART5803-Cohort D - Anti-N-methyl-D-aspartate Receptor (NMDAR) Encephalitis (ANRE), Anti-N-methyl-D-aspartate Receptor (NMDAR) Antibody-associated Psychiatric Disease | Phase 2 | Recruiting | Arialys Australia Pty Ltd | 30 | 2026-05-15 | 2026-10-27 |
| T-cell Therapy in Patients With PML Application of T-lymphocytes - Progressive Multifocal Leucoencephalopathy (PML) | Phase 2 | Recruiting | Hannover Medical School | 23 | 2026-02-06 | 2026-10-15 |
| Adjunctive Doxycycline for Central Nervous System Tuberculosis Doxycycline, Placebo, Anti Tuberculosis Drug - Tuberculosis, Meningeal, Tuberculosis; Meningitis (Etiology) | Phase 2 | Recruiting | National University Hospital, Singapore | 200 | 2025-08-21 | 2026-06-01 |
| High-Titer Neutralizing Plasma for West Nile Fever in Hospitalized Patients Plasma - West Nile Fever | Phase 2 | Recruiting | Gili Regev-Yochay MD | 37 | 2025-07-30 | 2025-08-26 |
| MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment Lenalidomide 10 mg - Cognitive Impairment, Mild, Cognitive Dysfunction | Phase 2 | Not yet recruiting | St. Joseph's Hospital and Medical Center, Phoenix | 45 | 2025-06-01 | 2025-05-18 |
| A Phase 2 Trial in Healthy Adult Participants of the Recombinant MVA-BN-WEV Vaccine MVA-BN-WEV, Placebo - Encephalitis | Phase 2 | Active not recruiting | Bavarian Nordic | 411 | 2025-03-10 | 2025-10-01 |
| A Study to Assess the Safety, Reactogenicity, and Immunogenicity of SK Japanese Encephalitis Messenger Ribonucleic Acid (mRNA) Vaccines (GBP560) in Healthy Adults GBP560-A, GBP560-B, IXIARO - Japanese Encephalitis Virus Disease | Phase 1 / Phase 2 | Completed | SK Bioscience Co., Ltd. | 161 | 2025-02-24 | 2026-09-11 |
| Efficacy and Safety of Taitacept in Treatment of Refractory or Recurrent Anti-NMDAR/anti-LGI1 Encephalitis Taitacept - Anti-N-Methyl-D-Aspartate Receptor Encephalitis | Phase 2 | Recruiting | Beijing Tongren Hospital | 10 | 2024-12-01 | 2024-11-20 |
| Early Interferon-beta Treatment for West-Nile Virus Infection Rebif 44 MCG Per 0.5 ML Prefilled Syringe, Saline - West Nile Virus, West Nile Fever Encephalitis | Phase 2 | Unknown | Tel-Aviv Sourasky Medical Center | 100 | 2024-07-14 | 2024-07-23 |
| Pembrolizumab in Progressive Multifocal Leukoencephalopathy (PML) in Immunocompromised Patients Without HIV Infection Pembrolizumab, 25 mg/ml solution for intravenous (IV) injection - Progressive Multifocal Leukoencephalopathy | Phase 2 / Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 33 | 2024-04-01 | 2024-02-26 |
| A Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PML CE-VST01-JC - Progressive Multifocal Leukoencephalopathy | Phase 2 | Unknown | Cellevolve Bio Inc | 60 | 2023-02-01 | 2022-09-16 |
| An Experimental Medicine Decipher of a Minimum Correlate of Cellular Immunity Stamaril, Imojev, Ixiaro - Infectious Disease, Yellow Fever | Phase 2 | Unknown | Singapore General Hospital | 70 | 2022-09-28 | 2023-04-12 |
| The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis Inebilizumab, Placebo - Autoimmune Encephalitis, Encephalitis | Phase 2 | Recruiting | University of Utah | 116 | 2022-03-30 | 2025-07-01 |
| Immunoadsorption Therapy in Managing NMDAR Antibodies Encephalitis IA session, Rituximab - Anti-NMDAR Encephalitis | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 20 | 2021-06-23 | 2026-08-10 |
| Safety and Immunogenicity Study of Venezuelan Equine Encephalomyelitis (VEE) Vaccine as Booster Vaccine in Adults 0.5 mL Inactivated, Dried, C-84, TSI-GSD 205, Lot 7, Run 1 - Venezuelan Equine Encephalomyelitis | Phase 2 | Not yet recruiting | U.S. Army Medical Research and Development Command | 500 | 2021-06-01 | 2021-02-16 |
| MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients Lenalidomide 10 mg, Placebo - Cognitive Impairment, Mild, Cognitive Dysfunction | Phase 2 | Completed | St. Joseph's Hospital and Medical Center, Phoenix | 15 | 2020-07-22 | 2026-06-10 |
| Trial to Evaluate Efficacy and Safety of Bortezomib in Patients With Severe Autoimmune Encephalitis Bortezomib, Placebo - Autoimmune Encephalitis | Phase 2 | Recruiting | Jena University Hospital | 50 | 2020-05-13 | 2025-09-04 |
Showing 20 of 65. Sign in to see all of them.
Encephalitis, Japanese (14) · Encephalitis, Tick-Borne (10) · Leukoencephalopathy, Progressive Multifocal (9) · Acquired Immunodeficiency Syndrome (5) · Autoimmune Diseases of the Nervous System (5) · West Nile Fever (5) · HIV Infections (4) · Meningitis (4) · Anti-N-Methyl-D-Aspartate Receptor Encephalitis (3) · Cognitive Dysfunction (3) · Encephalomyelitis, Venezuelan Equine (3) · Virus Diseases (3) · Yellow Fever (3) · Alzheimer Disease (2)
Brain Diseases (65) · Neuroinflammatory Diseases (65) · Central Nervous System Diseases (64) · Nervous System Diseases (64) · Infections (54) · Central Nervous System Infections (53) · Central Nervous System Viral Diseases (51) · Infectious Encephalitis (46) · Virus Diseases (46) · Encephalitis, Viral (45) · RNA Virus Infections (43) · Arbovirus Infections (36) · Encephalitis, Arbovirus (36) · Vector Borne Diseases (36)
Vaccines (4) · Desiccation (3) · Immunoglobulins, Intravenous (2) · Japanese Encephalitis Vaccines (2) · Lenalidomide (2) · Saline Solution (2) · pembrolizumab (2) · Amphotericin B (1) · Antitubercular Agents (1) · Atovaquone (1) · Bortezomib (1) · Cefiderocol (1) · Ceftazidime (1) · Clarithromycin (1) · Cytarabine (1)
U.S. Army Medical Research and Development Command (6) · Pfizer (5) · Sanofi (5) · National Institute of Allergy and Infectious Diseases (NIAID) (4) · Sanofi Pasteur, a Sanofi Company (3) · Assistance Publique - Hôpitaux de Paris (2) · Beijing Tongren Hospital (2) · National Institute of Hygiene and Epidemiology, Vietnam (2) · Singapore General Hospital (2) · Sormland County Council, Sweden (2) · St. Joseph's Hospital and Medical Center, Phoenix (2) · Arialys Australia Pty Ltd (1) · Bavarian Nordic (1) · BioVersys AG (1) · Biogen (1)
United States (23) · Germany (8) · Austria (5) · Australia (4) · Vietnam (4) · China (3) · France (3) · Singapore (3) · Finland (2) · India (2) · Israel (2) · Spain (2) · Sweden (2) · Thailand (2) · Brazil (1)
Anthony Cardile, DO (2) · Robert Rivard, MD (2) · Thiem D Vu, MD., PhD. (2) · Ulrich Behre, MD (2) · Ajit Rayamajhi, MBBS, MD (1) · Anand Dubey, M.D (1) · Anthony P Cardile, DO, MAJ (1) · Atul Shanker, Dr. (1) · Bakul B. Javadekar, M.D. (1) · Biao Zhu, PhD (1) · Boris Decourt, PhD (1) · Carlos A. Fierro, MD (1)
PMID 11113214, PMID 12393404, PMID 15564716, PMID 15714427, PMID 15817019, PMID 17262855, PMID 17538176, PMID 18417336, PMID 18851928, PMID 19143532, PMID 19680671, PMID 20427647, PMID 20605905, PMID 20829370, PMID 20856164, PMID 20864814, PMID 21148499, PMID 21150279, PMID 21163445, PMID 21738597, PMID 21865579, PMID 23151040, PMID 23290630, PMID 23733308, PMID 24360484, PMID 24763533, PMID 24884681, PMID 25392198, PMID 25573986, PMID 25872531, PMID 25886645, PMID 26187412, PMID 27267753, PMID 27399303, PMID 27412413, PMID 27575749, PMID 27686833, PMID 27815383, PMID 27886126, PMID 28296863, PMID 28403842, PMID 29143550, PMID 29159189, PMID 29293273, PMID 29406578, PMID 29476014, PMID 29549218, PMID 29956883, PMID 30304652, PMID 30578370
2005 (1), 2019 (1), 2023 (1), K01AG047279 (1), R01AG059008 (1)