23 completed, 8 recruiting, 6 unknown, 3 not yet recruiting. 33 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 33 | Completed 19, Recruiting 6, Unknown 4, Not yet recruiting 3, Terminated 1 |
| Phase 2 | 2 | Terminated 2 |
| Phase 3 | 2 | Unknown 1, Withdrawn 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Elevated Blood Pressure: new trials by email Literature Review of Elevated Blood Pressure trials Research Report on Elevated Blood Pressure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Know Your Pressures NYC Virtual Automated Navigator Intervention with Health Education, Usual Care - Glaucoma, Hypertension | Not applicable | Not yet recruiting | Columbia University | 7085 | 2027-07-01 | 2026-08-25 |
| No Time to Pause: Physical Activity to Improve Health of Midlife Hispanic Women Physical activity intervention - Elevated Blood Pressure, Perimenopause | Not applicable | Not yet recruiting | The University of Texas Medical Branch, Galveston | 40 | 2027-01-20 | 2025-12-08 |
| Feasibility of a Community-Integrated Isometric Handgrip Exercise Program and Its Preliminary Effects on Blood Pressure and Cognitive Function in Older Adults Zona Plus 4-Week Isometric Handgrip Exercise Intervention, Squegg 4-Week Isometric Handgrip Exercise Intervention - Hypertension, Elevated Blood Pressure | Not applicable | Recruiting | McMaster University | 30 | 2026-08-18 | 2026-10-07 |
| HJB647 Phase 1b Study in Japanese Healthy Participants With Elevated Blood Pressure and Patients With Hypertension HJB647, Placebo - Elevated Blood Pressure, Hypertension | Phase 1 | Recruiting | Novartis Pharmaceuticals | 64 | 2026-07-02 | 2026-07-22 |
| The Acute Effect of Exercise Type And Timing on Ambulatory Blood Pressure and Intra-Ocular Pressure in Individuals With Glaucoma (The ACHIEVE-project). Exercise - Glaucoma Open-Angle Primary, Hypertension | Not applicable | Not yet recruiting | KU Leuven | 60 | 2026-04-01 | 2026-02-17 |
| Groceries for Residents of Southeastern USA to Stop Hypertension Dietitian-Assisted DASH groceries, Self-directed shopping - Hypertension, Elevated Blood Pressure | Not applicable | Recruiting | Beth Israel Deaconess Medical Center | 150 | 2025-10-14 | 2026-08-19 |
| Sodium-rich COndiments Unifying Health and Taste Control porridge with no condiments, Porridge with light soya sauce, Porridge with fermented bean paste - Elevated Blood Pressure, Vascular Health | Not applicable | Recruiting | Singapore Institute of Food and Biotechnology Innovation | 32 | 2025-09-22 | 2026-02-09 |
| Study to Investigate the Potential Health Benefits of Grapes Seeds Extract Supplementation in the Management of Elevated Blood Pressure or Stage 1 Hypertension Enovita® (Grape Seed Extract), Placebo Capsule - Elevated Blood Pressure, Hypertension | Not applicable | Completed | Liaquat University of Medical & Health Sciences | 80 | 2025-08-01 | 2025-12-05 |
| Evaluation of a Nigella Sativa Extract (10% Thymoquinone, Nisatol®) in Perimenopausal Women With Metabolic Syndrome Nigella sativa extract (Nisatol®), Mediterranean Diet - Metabolic Syndrome, Elevated Blood Pressure | Not applicable | Completed | Liaquat University of Medical & Health Sciences | 50 | 2025-06-15 | 2025-12-30 |
| Blood Pressure Following Isometric Exercise in Inactive Adults Isometric Exercise Training (IET), Expectation-Enhancing Informational Framing - Hypertension, Elevated Blood Pressure | Not applicable | Recruiting | Canterbury Christ Church University | 36 | 2025-04-21 | 2025-05-16 |
| A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects Zona Plus Device, Relaxing Music App - Elevated Blood Pressure, Hypertension | Not applicable | Recruiting | Zona Health, Inc | 160 | 2025-03-27 | 2026-07-24 |
| WeArable teChnology daTa driVen digitAl healTh cOachINg (ACTIVATION)- A Mixed-methods Study Smart watch, Dashboard with nudging system, Digital Health Coach (DHC) - Elevated Blood Pressure, Hypertension | Not applicable | Recruiting | Alexandra Hospital | 1700 | 2024-08-06 | 2025-10-02 |
| Acute Effect Of Pilates On Blood Pressure In Women Pilates Exercise, Walking Exercise - Elevated Blood Pressure | Not applicable | Completed | Universidade Estadual do Norte do Parana | 15 | 2024-08-01 | 2026-09-14 |
| Post-exercise Hot Water Immersion to Improve Overnight Blood Pressure Exercise, Heat Therapy, Sham leg bath - Elevated Blood Pressure | Not applicable | Completed | Providence College | 20 | 2024-07-01 | 2026-06-01 |
| Walking and Blood Pressure in Older Adults With Respiratory Impairment. Increased lifestyle walking (intervention), Health education only (control) - Respiratory Impairment, Elevated Blood Pressure | Not applicable | Unknown | Iowa State University | 30 | 2023-09-01 | 2023-09-13 |
| Treatment of Elevated Blood Pressures in Early Pregnancy Nifedipine, Labetalol - Elevated Blood Pressure, Pregnancy Induced Hypertension | Phase 2 | Terminated | Marshall University | 2 | 2023-07-11 | 2024-11-21 |
| Open Label Clinical Trial of Vascanox® HP on Nitric Oxide and Blood Pressure Vascanox® HP - Hypertension, Elevated Blood Pressure | Not applicable | Completed | Calroy Health Sciences | 12 | 2023-06-24 | 2023-08-02 |
| Effect of Mental and Physical Training on Blood Pressure Mental training, Physical training, Mental & physical training - Elevated Blood Pressure | Not applicable | Completed | Universiti Tunku Abdul Rahman | 62 | 2022-10-25 | 2023-01-30 |
| Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension Dietitian-Assisted DASH groceries, Self-directed shopping - Elevated Blood Pressure, Hypertension | Not applicable | Completed | Beth Israel Deaconess Medical Center | 180 | 2022-09-30 | 2026-06-11 |
| Effect of TOTUM-854 on Blood Pressure in Subjects With Moderately Elevated Blood Pressure TOTUM-854, Placebo - Prehypertension, Elevated Blood Pressure | Not applicable | Unknown | Valbiotis | 410 | 2022-07-15 | 2024-04-23 |
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Hypertension (44) · Motor Activity (5) · Obesity (5) · Overweight (4) · Prehypertension (4) · Cardiovascular Diseases (3) · Diabetes Mellitus, Type 2 (2) · Metabolic Syndrome (2) · Sedentary Behavior (2) · Sleep Wake Disorders (2) · Aneurysm (1) · Atherosclerosis (1) · Body Weight (1) · Fasting (1) · Glaucoma (1)
Vascular Diseases (44) · Cardiovascular Diseases (41) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Behavior (8) · Nutritional and Metabolic Diseases (8) · Body Weight (5) · Nutrition Disorders (5) · Overnutrition (5) · Glucose Metabolism Disorders (4) · Metabolic Diseases (4) · Mental Disorders (3) · Nervous System Diseases (3) · Diabetes Mellitus (2) · Endocrine System Diseases (2)
Exercise (3) · Actigraphy (2) · Grape Seed Extract (2) · Aspirin (1) · Diathermy (1) · Diet, Mediterranean (1) · Diet, Sodium-Restricted (1) · Dietary Approaches To Stop Hypertension (1) · Exercise Movement Techniques (1) · High-Intensity Interval Training (1) · Labetalol (1) · Melatonin (1) · Methods (1) · Nifedipine (1) · Physical Conditioning, Human (1)
Johns Hopkins University (3) · Beth Israel Deaconess Medical Center (2) · Columbia University (2) · Liaquat University of Medical & Health Sciences (2) · Marymount University (2) · Valbiotis (2) · Alexandra Hospital (1) · Calroy Health Sciences (1) · Canterbury Christ Church University (1) · Children's Hospital Medical Center, Cincinnati (1) · China National Center for Cardiovascular Diseases (1) · Colorado State University (1) · Iowa State University (1) · KU Leuven (1) · Marshall University (1)
United States (25) · Canada (2) · Singapore (2) · Belgium (1) · Brazil (1) · Bulgaria (1) · China (1) · France (1) · Germany (1) · Indonesia (1) · Ireland (1) · Italy (1) · Japan (1) · Malaysia (1) · Netherlands (1)
Alexei Wong, Ph.D (1) · Brett R Ely, PhD (1) · Brian D Modena, MD (1) · Carolyn Moore, PHD, RD, LD (1) · Daniel Menzel, MD (1) · Duck-chul Lee, PhD (1) · Dylan Mackay, PhD (1) · Elaine Urbina (1) · Elizabeth Lorenzo, PhD, RN (1) · Hillart Hosier, MD (1) · Jennifer Heisz, PhD (1) · Jessica R Wilson, MD, MSCI (1) · Jing Li, MD,PhD (1) · John Durocher, PhD (1)
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K23HL141682 (1), P50MH115842 (1), R01NR018891 (1), R15HL140596 (1), R56HL139620 (1)