23 completed, 3 not yet recruiting, 3 unknown, 1 suspended. 25 Not applicable, 3 Phase 3, 2 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 25 | Completed 18, Not yet recruiting 3, Unknown 3, Suspended 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 1 | Completed 1 |
Follow Grape Seed Extract: new trials by email Literature Review of Grape Seed Extract trials Research Report on Grape Seed Extract
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Revascularization of Young Immature Permenant Teeth Using Different Types of Intra Canal Medication Grape Seed Extract, Glycyrrhizin, Triple Antibiotic Paste - Traumatic Teeth, Necrotic Teeth | Not applicable | Not yet recruiting | Al-Azhar University | 45 | 2025-12-01 | 2025-11-19 |
| Chronic Grape Extract in Crosstraining Athletes: A Randomized Crossover Trial Grape Seed Extract, Placebo - Performance | Not applicable | Not yet recruiting | Universidad de Granada | 30 | 2025-09-01 | 2025-08-06 |
| Study to Investigate the Potential Health Benefits of Grapes Seeds Extract Supplementation in the Management of Elevated Blood Pressure or Stage 1 Hypertension Enovita® (Grape Seed Extract), Placebo Capsule - Elevated Blood Pressure, Hypertension | Not applicable | Completed | Liaquat University of Medical & Health Sciences | 80 | 2025-08-01 | 2025-12-05 |
| Clinical Performance of Resin Composite Restoration After Dentin Biomodification by Grape Seed Extract in Deep Carious Lesions. 15% Grape seed extract as dentin pretreatment - Deep Carious Lesions | Not applicable | Not yet recruiting | Cairo University | 60 | 2025-06-01 | 2025-01-17 |
| Effectiveness of a Grape Seed Extract on Circulatory Measures in Healthy Adults Grape Seed Extract, Maltodextrin - Circulatory; Change | Phase 3 | Completed | RDC Clinical Pty Ltd | 35 | 2024-10-31 | 2026-03-06 |
| Effect of Acute Grape Seed Extract Supplementation on the Heart Rate Recovery in Young Individuals 600 mg grape seed extract, 600 mg Starch - Healthy Young Men | Not applicable | Completed | California Baptist University | 12 | 2024-10-03 | 2025-08-22 |
| Grape Seed Extract VS Low Level Laser Therapy for Dentin Hypersensitivity Grape Seed Extract, Low-level laser therapy - Dentin Hypersensitivity | Not applicable | Unknown | Manipal University College Malaysia | 30 | 2023-05-15 | 2023-07-03 |
| Grape Seed Extract Supplementation on Cycling Time-to-Exhaustion Performance. Grape seed extract - Healhty | Not applicable | Completed | China Medical University Hospital | 10 | 2023-01-09 | 2026-10-09 |
| Effects of Acute Grape Seed Extract Supplementation on Muscle Metaboreflex in Healthy Young Individuals Grape seed extract - Dietary Supplementation | Not applicable | Completed | California Baptist University | 12 | 2022-05-01 | 2023-07-14 |
| Effect of 7 Days of Grape Seed Extract Supplementation on Cold Pressor Test and Muscle Metaboreflex in Individuals With Elevated and Stage 1 Hypertension Grape Seed Extract, Placebo - Prehypertension | Not applicable | Completed | California Baptist University | 12 | 2022-03-01 | 2024-05-24 |
| Remineralizing Efficacy of Grape Seed Extract in Management of White Spot Lesion in Post Orthodontic Treated Patients. Grape seed extract mouthwash, Sodium fluoride mouthwash - Dental Caries | Not applicable | Completed | Cairo University | 40 | 2021-02-10 | 2025-01-17 |
| Metabotypes in the Urinary Excretion of Flavan-3-ol Metabolites: "Metanols" Inulin, green tea extract, grape seed - Diet Modification | Not applicable | Suspended | University of Parma | 50 | 2019-09-02 | 2021-04-30 |
| Effects of Chronic Dietary Grape Seed Extract Supplementation on Aortic Stiffness and Hemodynamic Responses to Exercise in Obese Males Grape Seed Extract - Obesity Adult Onset | Not applicable | Completed | California Baptist University | 10 | 2019-09-01 | 2020-07-13 |
| Effects of Combined Grape Seed Extract and L-citrulline Supplementation on Hemodynamic Responses in Young Males Grape seed extract, Placebo - Dietary Supplementation | Not applicable | Completed | California Baptist University | 11 | 2019-06-01 | 2021-11-10 |
| Effect of Acute Dietary Supplementation With Grape Seed Extract on Aortic Stiffness, Arterial Pressure, and Blood Vessel Dilation in Collegiate Obese Individuals at Rest Grape seed extract - Obesity | Not applicable | Completed | California Baptist University | 20 | 2019-03-01 | 2020-05-15 |
| A Study of Grape Seed Extract in Asymptomatic Non-Metastatic Prostate Cancer Patients With Rising PSA Grape Seed Extract - Prostate Cancer | Not applicable | Completed | University of Colorado, Denver | 41 | 2018-01-18 | 2025-03-25 |
| One Year Clinical Evaluation of E.Max Laminate Veneers With and Without Using Grape Seed Extract as a Natural Collagen Cross-linking Agent Before Bonding Grape seed extract - Retention & Fracture of Emax Laminate Veneers | Not applicable | Unknown | Marwa Salem | 16 | 2016-11-01 | 2016-10-20 |
| The Effects of Resveratrol on the Complications of Patients With Hemodialysis resveratrol, Placebo - Chronic Kidney Disease | Not applicable | Completed | Dalin Tzu Chi General Hospital | 36 | 2014-11-01 | 2017-11-24 |
| Phase I Assay-guided Trial of Anti-inflammatory Phytochemicals in Patients With Advanced Cancer Grape Seed Extract, Vitamin D - Solid Cancers | Phase 1 | Completed | Medical University of South Carolina | 22 | 2013-03-01 | 2018-05-18 |
| Effect of a Grape Seed Extract (GSE) on Insulin Resistance Grape Seed Extract, Placebo - Metabolic Syndrome | Not applicable | Completed | University of California, Davis | 19 | 2012-11-01 | 2017-06-27 |
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Hypertension (5) · Metabolic Syndrome (3) · Breast Neoplasms (1) · Coronary Artery Disease (1) · Dental Caries (1) · Dental Plaque (1) · Dentin Sensitivity (1) · Fatigue (1) · Heart Failure (1) · Heart Failure, Diastolic (1) · Hyperlipidemias (1) · Hypertriglyceridemia (1) · Inflammation (1) · Insulin Resistance (1) · Obesity (1)
California Baptist University (6) · University of California, Davis (3) · Cairo University (2) · Al-Azhar University (1) · Boston University (1) · China Medical University Hospital (1) · Clinical Nutrition Research Center, Illinois Institute of Technology (1) · Dalin Tzu Chi General Hospital (1) · Liaquat University of Medical & Health Sciences (1) · Manipal University College Malaysia (1) · Marwa Salem (1) · Mayo Clinic (1) · Medical University of South Carolina (1) · RDC Clinical Pty Ltd (1) · Shahid Beheshti University of Medical Sciences (1)
United States (15) · Egypt (2) · Iran (2) · Taiwan (2) · Australia (1) · France (1) · Italy (1) · Malaysia (1) · Netherlands (1) · Pakistan (1) · Spain (1)
Jong-Kyung Kim, Ph.D (2) · Abbas Delazar, PhD (1) · Ahmad Reza Jodati, MD (1) · Ali Eskandari, MD (1) · Alireza Yaghobi, MD (1) · Amanda Rao, PhD (1) · Britt Burton-Freeman, PhD (1) · Chulani T Kappagoda, M.D., Ph. D. (1) · Chulani T Kappagoda, M.D., Ph.D. (1) · Chulani T Kappagoda, MD, PhD (1) · Daniele DR Del Rio, Professor (1) · Dietlind L. Wahner-Roedler, M.D. (1) · Furio FB Brighenti, Professor (1)
PMID 21167964, PMID 28735851, PMID 29176304, PMID 33905304, PMID 35704241, PMID 36013786, PMID 36460919, PMID 36504246, PMID 38584280, PMID 38962594, PMID 41696662, PMID 42801665