4 unknown, 3 completed, 2 terminated, 1 active not recruiting. 10 Phase 2, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Unknown 4, Completed 3, Terminated 2, Active not recruiting 1 |
| Phase 1 | 4 | Completed 2, Unknown 2 |
| Phase 3 | 1 | Unknown 1 |
Follow Drug Toxicity: new trials by email Literature Review of Drug Toxicity trials Research Report on Drug Toxicity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Expanded UCMSCs On Patients With Moderate to Severe Psoriasis Umbilical cord mesenchymal stem cells - Mesenchymal Stromal Cells, Psoriasis | Phase 1 / Phase 2 | Unknown | Guangdong Provincial Hospital of Traditional Chinese Medicine | 5 | 2021-08-31 | 2021-02-09 |
| Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNS Glucarpidase 1000 UNT [Voraxaze] - Diffuse Large B-Cell Lymphoma, Drug Toxicity | Phase 2 | Terminated | Fundacion CRIS de Investigación para Vencer el Cáncer | 3 | 2021-07-19 | 2024-05-13 |
| Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis Infliximab, Methylprednisolone, Prednisone - Melanoma Stage III, Melanoma Stage IV | Phase 2 | Active not recruiting | Massachusetts General Hospital | 42 | 2020-08-31 | 2026-10-29 |
| Selinexor as Single Agent and With Imatinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (SeliGIST) Selinexor, Imatinib - Maximum Tolerated Dose, GIST | Phase 1 / Phase 2 | Unknown | Grupo Espanol de Investigacion en Sarcomas | 30 | 2019-08-16 | 2023-03-27 |
| Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment in Patients With Moderate to Severe Psoriasis Calcipotriol ointment, adipose-derived multipotent mesenchymal stem cells - Mesenchymal Stromal Cells, Psoriasis | Phase 1 / Phase 2 | Completed | Guangdong Provincial Hospital of Traditional Chinese Medicine | 8 | 2019-07-23 | 2023-08-24 |
| Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma （GTN） Patients With Score of 5-6 MTX, MTX+ACTD - Gestational Trophoblastic Tumor, Effects of Chemotherapy | Phase 2 / Phase 3 | Unknown | Women's Hospital School Of Medicine Zhejiang University | 300 | 2019-03-08 | 2019-03-21 |
| Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis adipose-derived multipotent mesenchymal stem cells - Mesenchymal Stromal Cells, Psoriasis | Phase 1 / Phase 2 | Completed | Guangdong Provincial Hospital of Traditional Chinese Medicine | 7 | 2017-09-24 | 2023-08-25 |
| High-Dose,Pulsatile Erlotinib/Gefitinib for Advanced NSCLC Patients After Failure of Standard Dose EGFR-TKIs Erlotinib or Gefitinib - Self Efficacy, Drug Toxicity | Phase 2 | Unknown | Anhui Medical University | 20 | 2013-10-01 | 2017-05-08 |
| Triptorelin for Preserving Ovarian Function in Premenopausal Women Receiving Chemotherapy for Early-Stage Breast Cancer triptorelin - Breast Cancer, Hormone Changes | Phase 2 | Terminated | University of South Florida | 49 | 2004-07-01 | 2021-01-28 |
| 13-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung Cancer 13-cis retinoic acid, Tocopherol - Drug Toxicity, Lung Cancer | Phase 2 | Completed | University of Colorado, Denver | 96 | 1993-01-01 | 2020-05-15 |
Drug-Related Side Effects and Adverse Reactions (10) · Psoriasis (3) · Breast Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Colitis (1) · Gestational Trophoblastic Disease (1) · Lung Neoplasms (1) · Lymphoma, Large B-Cell, Diffuse (1) · Melanoma (1) · Neoplasm Metastasis (1) · Sarcoma (1) · Skin Neoplasms (1) · Small Cell Lung Carcinoma (1)
Chemically-Induced Disorders (10) · Neoplasms (6) · Skin Diseases (5) · Skin and Connective Tissue Diseases (5) · Neoplasms by Histologic Type (4) · Neoplasms by Site (3) · Skin Diseases, Papulosquamous (3) · Neoplasms, Germ Cell and Embryonal (2) · Breast Diseases (1) · Bronchial Neoplasms (1) · Carcinoma, Bronchogenic (1) · Colonic Diseases (1) · Digestive System Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Gastroenteritis (1)
Drug Combinations (1) · Erlotinib Hydrochloride (1) · Gefitinib (1) · Imatinib Mesylate (1) · Infliximab (1) · Isotretinoin (1) · Methotrexate (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1) · Pharmaceutical Preparations (1) · Prednisone (1) · Tocopherols (1) · Triptorelin Pamoate (1) · Vitamin E (1) · glucarpidase (1)
Guangdong Provincial Hospital of Traditional Chinese Medicine (3) · Anhui Medical University (1) · Fundacion CRIS de Investigación para Vencer el Cáncer (1) · Grupo Espanol de Investigacion en Sarcomas (1) · Massachusetts General Hospital (1) · University of Colorado, Denver (1) · University of South Florida (1) · Women's Hospital School Of Medicine Zhejiang University (1)
China (5) · United States (3) · Spain (2)
Adolfo De la Fuente, PD (1) · Cesar Serrano, MD (1) · Chuanjian Lu (1) · Chuanjian Lu, PhD (1) · Long Nguyen, MD, MS (1) · Pamela N. Munster, MD (1) · Weiguo Lu, MD. (1) · York E. Miller, MD (1) · Yueyin Pan, PHD,MD (1)
2017 (1), P30CA076292 (1)