19 completed, 11 unknown, 3 recruiting, 3 terminated. 10 Not applicable, 10 Phase 2, 7 Phase 3, 7 Phase 4, 3 Phase 1.
Follow Tocopherols: new trials by email Literature Review of Tocopherols trials Research Report on Tocopherols
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose) Pravastatin (drug), Pentoxifylline, ketoprofen - Fibrosis Syndrome, Lymphedema | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 250 | 2025-08-08 | 2026-07-24 |
| Vitamin E Plus Mefenamic Acid Versus Mefenamic Acid Alone for Treating Primary Dysmenorrhea in Women Mefenamic acid, Vitamin E capsule - Dysmenorrhea Primary, Vitamin E | Phase 4 | Completed | Nishtar Medical University | 60 | 2025-07-15 | 2026-03-12 |
| Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE) Pravastatin, Pentoxifylline, Tocopherol - Lymphedema, Fibrosis | Phase 2 | Recruiting | M.D. Anderson Cancer Center | 295 | 2025-02-13 | 2026-09-11 |
| Combination Therapy: Hyperbaric Oxygen and PENTOCLO for Treatment of Osteoradionecrosis of the Mandible modified PENTOCLO (mPENTOCLO), sham mPENTOCLO - Osteoradionecrosis, Osteoradionecrosis of Jaw | Phase 3 | Recruiting | Sunnybrook Health Sciences Centre | 24 | 2025-01-16 | 2025-09-12 |
| Comparison of Effectiveness of Obeticholic Acid With Vitamin E in Patients of Non-alcoholic Fatty Liver Disease Obeticholic Acid 10 MG, Vitamin E 400mg - Non Alcoholic Fatty Liver Disease | Phase 2 | Completed | King Edward Medical University | 90 | 2023-08-24 | 2025-08-05 |
| The Effect of Vitamin C and E Therapy on Restless Leg Syndrome in Patients With End Stage Renal Disease on Haemodialysis Ascorbic acid, Tocopherol, Placebo capsule - Restless Legs Syndrome, End Stage Renal Disease | Phase 3 | Unknown | King Abdulaziz University | 160 | 2022-11-01 | 2022-08-24 |
| Antioxidants Vitamins and Muscle Damage Dietary Supplement: Vitamin C and vitamin E, Placebo - Oxidative Stress | Not applicable | Completed | Universidad Europea de Madrid | 18 | 2022-02-10 | 2022-04-07 |
| Clinical Efficacy Analysis of Resveratrol in the Treatment of Primary Ovarian Insufficiency Resveratrol, Vitamin E - Primary Ovarian Insufficiency | Not applicable | Unknown | Affiliated Hospital of Nantong University | 150 | 2022-02-01 | 2022-06-08 |
| OMTrigger Inject- Treating Trigger Points: Comparing Muscle Energy Technique vs. Lidocaine Needling Technique OMT - Myofascial Pain Syndrome | Terminated | AtlantiCare Regional Medical Center | 30 | 2022-01-12 | 2025-02-03 | |
| Role of Vitamin E in Reducing Dry Socket Vitamin E application - Dry Socket | Phase 4 | Completed | Ain Shams University | 40 | 2022-01-01 | 2023-08-09 |
| The Effect of Vitamin D Supplementation on Dental Implant Osseointegration: A Randomized Controlled Trial Vitamin D3, Vitamin E 400 - Osseointegration Failure of Dental Implant | Not applicable | Completed | Ziauddin University | 100 | 2021-09-01 | 2024-02-23 |
| Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer. All trans-retinoic acid, 13-Cis Retinoic Acid plus Tocopherol, Mifepristone - Breast Cancer Female | Phase 3 | Unknown | Mahmoud Ramadan mohamed Elkazzaz | 160 | 2021-08-01 | 2021-08-23 |
| Antioxidant Vitaminas and Hypertrophy Adaptations to Resistance Training Vitamin C and vitamin E, Placebo - Hypertrophy | Not applicable | Completed | Universidad Europea de Madrid | 30 | 2021-02-01 | 2021-08-03 |
| Omega-3 Fatty Acids Plus Vitamin E Cosupplementation Versus Vitamin E in Fibrocystic Breast Patient Omega 3 fatty acid, VitaE - Mastalgia | Phase 4 | Unknown | Cairo University | 120 | 2021-01-01 | 2021-01-05 |
| Impact of Topical Pentoxifylline and Tocopherol in Treatment and Prevention of Medically-related Osteonecrosis of the Jaws Tocopherol and pentoxifilline topical gel, Placebo - Medically Related Osteonecrosis of the Jaws | Not applicable | Completed | University of Catania | 48 | 2020-04-02 | 2024-05-10 |
| Lipid Peroxidation and Options Antioxidant Therapy for Secondary Lymphedema of the Lower Extremities Micronised purified flavonoid fraction (diosmin+flavonoids expressed as hesperidin), Tocopherol, Elastic compression - Lower Extremity Lymphedema | Phase 4 | Completed | Ryazan State Medical University | 120 | 2019-09-01 | 2022-08-04 |
| Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome. Q10 Ubiquinol, Vitamin E, Multi-Vitamin B complex - Autism Spectrum Disorder, Phelan-McDermid Syndrome | Not applicable | Unknown | Antonio Persico | 200 | 2019-03-09 | 2020-03-18 |
| Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ) Pentoxifylline, Placebo, Tocopherol - Medication-related Osteonecrosis of the Jaw, Bisphosphonate-related Osteonecrosis of the Jaw | Phase 3 | Active not recruiting | University of Washington | 100 | 2018-04-01 | 2026-04-29 |
| Management of Mandibular ORN: PENTO as Medical Treatment Pentoxifylline and Tocopherol - Osteoradionecrosis | Phase 4 | Completed | Hospital Vall d'Hebron | 24 | 2016-02-01 | 2018-03-22 |
| ANti-Oxidant in Variant Angina (ANOVA) Trial Vitamin C and Vitamin E, Statin, Standard medication for variant angina - Variant Angina | Phase 4 | Terminated | Seoul National University Hospital | 320 | 2014-09-01 | 2026-04-27 |
Showing 20 of 38. Sign in to see all of them.
Fibrosis (3) · Head and Neck Neoplasms (2) · Kidney Failure, Chronic (2) · Low Back Pain (2) · Lymphedema (2) · Osteonecrosis (2) · Osteoradionecrosis (2) · Renal Insufficiency, Chronic (2) · Alzheimer Disease (1) · Anemia (1) · Angina Pectoris, Variant (1) · Autism Spectrum Disorder (1) · Autistic Disorder (1) · Avitaminosis (1) · Bisphosphonate-Associated Osteonecrosis of the Jaw (1)
M.D. Anderson Cancer Center (2) · Universidad Europea de Madrid (2) · Vanderbilt University (2) · Affiliated Hospital of Nantong University (1) · Aga Khan University (1) · Ain Shams University (1) · Antonio Persico (1) · AtlantiCare Regional Medical Center (1) · Cairo University (1) · Chandan K Sen (1) · Federal University of Health Science of Porto Alegre (1) · French National Agency for Research on AIDS and Viral Hepatitis (1) · Hadassah Medical Organization (1) · Hospital Universitario de Canarias (1) · Hospital Vall d'Hebron (1)
United States (14) · Pakistan (4) · Spain (4) · Canada (2) · Egypt (2) · France (2) · Italy (2) · Australia (1) · Brazil (1) · China (1) · Israel (1) · Netherlands (1) · Russia (1) · South Korea (1) · Thailand (1)
Alp Ikizler, MD (2) · Jonathan Himmelfarb, MD (2) · Abbot R. Laptook, MD (1) · Abhik Das, PhD (1) · Adis Tasanarong, MD (1) · Amr Ahmed (1) · Antonio M. Persico, MD (1) · Arthur J Dalton, PhD (1) · Barbara J. Stoll, MD (1) · Ben Safa, MD (1) · Brenda B. Poindexter, MD MS (1) · Brendan S Kelly, DO (1) · Chandan Sen, PhD (1) · Clifton Fuller, MD (1)
PMID 12190139, PMID 19401528, PMID 19845233, PMID 22298568, PMID 24218460, PMID 26780276, PMID 29939770, PMID 31461186, PMID 31776782, PMID 32663271, PMID 34872836, PMID 35178319, PMID 35403929, PMID 35866376, PMID 37702300, PMID 8931529
R01AG016381 (1), U10HD021364 (1), U10HD021373 (1), U10HD021385 (1), U10HD027851 (1), U10HD027856 (1), U10HD027871 (1), U10HD027880 (1), U10HD027904 (1), U10HD034216 (1), U10HD036790 (1), U10HD040492 (1), U10HD040689 (1), U10HD053089 (1), U10HD053109 (1)