41 completed, 7 unknown, 3 active not recruiting, 2 recruiting. 29 Phase 1, 10 Not applicable, 6 Phase 4, 1 Phase 2.
Follow Drug Interaction: new trials by email Literature Review of Drug Interaction trials Research Report on Drug Interaction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity PF-08653944, Acetaminophen - Obesity, Overweight and/or Obesity | Phase 1 | Active not recruiting | Pfizer | 22 | 2026-03-31 | 2026-07-09 |
| A Study to Investigate the Effect of Linaprazan Glurate on the Pharmacokinetics of Amoxicillin Drug Drug Interaction - Drug Interaction, GERD (Gastroesophageal Reflux Disease) | Phase 1 | Completed | Cinclus Pharma Holding AB | 12 | 2025-11-11 | 2026-02-27 |
| Pharmacogenomic and Circulating Biomarkers for CDK4/6 Inhibitors Whole gene sequencing, Drug-drug interaction analysis, Biomarker analysis - CDK4/6 Inhibitor, Breast Cancer | Enrolling by invitation | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 100 | 2025-10-10 | 2025-12-12 | |
| Drug Interaction Study of ZYN002 Transdermal Gel and Probe Substrates Part 1, Part 2 - Drug Interaction | Phase 1 | Completed | Harmony Biosciences Management, Inc. | 29 | 2025-06-06 | 2026-02-09 |
| Variation in Drug Interactions in People With HIV (PLWH) Aged 60 Years and Older. HIV Infections, Drug Interaction | Recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 50 | 2024-10-11 | 2024-12-05 | |
| Clinical Investigation Evaluating the Use of NETSmart Solution , Incorporated to NETSoins Software, in the Care and Support of Elderly People Living in Nursing Homes NETSmart software - Pressure Injury, Fall Prevention | Not applicable | Terminated | Teranga Software | 30 | 2024-09-03 | 2025-06-18 |
| KF2022#4-trial: Effects of a Beta Blocker and NSAID on CYP Mediated Drug Metabolism Caffeine Tablet, Bupropion Hydrochloride Capsels, Repaglinide Capsels - Drug Interaction | Not applicable | Completed | Helsinki University Central Hospital | 12 | 2024-08-22 | 2026-03-06 |
| Evaluation of Vamorolone CYP3A4 Induction on Midazolam (a Sensitive CYP 3A4 Substrate) Pharmacokinetics Vamorolone, Midazolam - Drug Interaction | Phase 1 | Completed | Santhera Pharmaceuticals | 18 | 2024-08-13 | 2025-12-15 |
| Drug Interactions in Hospital Information System. The PRoSIT System.. Discharge Prescription - Drug Interaction | Completed | University Hospital, Bordeaux | 5769 | 2024-05-13 | 2026-01-15 | |
| An Evaluation of Healthcare Providers' Adherence to Pharmacovigilance Practices in an African Community questionner - Drug Reaction, Drug Hypersensitivity | Completed | Deraya University | 300 | 2024-02-18 | 2024-08-07 | |
| Clinical Study to Evaluate Cannabidiol Liver Enzyme Elevations and Drug Interactions Cannabidiol, Placebo, Citalopram - Cannabidiol, Drug Induced Liver Injury | Phase 1 | Completed | Food and Drug Administration (FDA) | 241 | 2024-02-08 | 2025-07-31 |
| QSPainRelief-STRAT Opioid drug + CNS-acting add-on drug - Chronic Pain, Analgesia | Not applicable | Unknown | Université Catholique de Louvain | 150 | 2024-02-01 | 2024-02-06 |
| Drug Interaction Study Itraconazole, rifampicin, Ecopipam - Drug Interaction | Phase 1 | Completed | Emalex Biosciences Inc. | 45 | 2024-01-18 | 2024-09-19 |
| A Study to Evaluate Drug-drug Interaction of ZX-7101A Tablets and Oseltamivir Phosphate Capsules in Healthy Adult Subjects ZX-7101A, Oseltamivir, ZX-7101A and Oseltamivir - Drug Interaction | Phase 1 | Completed | Nanjing Zenshine Pharmaceuticals | 18 | 2023-08-28 | 2024-11-04 |
| A Big Data Approach to Predict NEOnatal Acute Kidney Injury in Newborns expoSed to nephroTOxic Drugs (NeoAKI STOP) Acute Kidney Injury, Drug Use | Unknown | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 4200 | 2023-08-01 | 2023-05-09 | |
| A Trial to Evaluate the Impact of C21 on the Exposure of 4 Substrates in Healthy Volunteers Drug Drug Interaction - Drug Interaction | Phase 1 | Completed | Vicore Pharma AB | 19 | 2023-03-29 | 2025-01-03 |
| Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia ALL, Childhood, Pediatric Cancer | Recruiting | University of Geneva, Switzerland | 556 | 2022-12-01 | 2026-01-15 | |
| Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam Linaprazan glurate, Drug drug interaction (DDI) - Clarithromycin (Part I), Drug drug interaction (DDI) - Midazolam (Part 2) - Safety Issues, Pharmacokinetics | Phase 1 | Completed | Cinclus Pharma Holding AB | 35 | 2022-11-27 | 2025-01-03 |
| The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia Bispectral index (BIS) or Patient State Index (PSI), Propofol, Alfentanil - Anesthesia, Drug Interaction | Unknown | Taipei Veterans General Hospital, Taiwan | 60 | 2022-10-01 | 2022-09-07 | |
| Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates for Drug Metabolism and Transport Ecopipam, Cohort 1 Probe Substrate Cocktail, Cohort 2 Probe Substrate - Drug Interaction | Phase 1 | Completed | Emalex Biosciences Inc. | 56 | 2022-04-26 | 2022-12-12 |
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Drug-Related Side Effects and Adverse Reactions (9) · COVID-19 (3) · HIV Infections (2) · Neoplasms (2) · Acute Kidney Injury (1) · Agnosia (1) · Breast Neoplasms (1) · Cardiovascular Abnormalities (1) · Cardiovascular Diseases (1) · Chemical and Drug Induced Liver Injury (1) · Chronic Pain (1) · Contraception Behavior (1) · Diabetes Mellitus, Type 2 (1) · Drug Hypersensitivity (1) · Gastroesophageal Reflux (1)
Chemically-Induced Disorders (11) · Infections (5) · RNA Virus Infections (5) · Virus Diseases (5) · Nutritional and Metabolic Diseases (4) · Coronaviridae Infections (3) · Coronavirus Infections (3) · Immune System Diseases (3) · Lung Diseases (3) · Nidovirales Infections (3) · Pathological Conditions, Signs and Symptoms (3) · Pneumonia (3) · Pneumonia, Viral (3) · Respiratory Tract Diseases (3) · Respiratory Tract Infections (3)
Midazolam (6) · Caffeine (3) · Drug Interactions (3) · Omeprazole (3) · Pantoprazole (3) · Bupropion (2) · Cannabidiol (2) · Clarithromycin (2) · Dextromethorphan (2) · Dorzagliatin (2) · Flurbiprofen (2) · Rifampin (2) · Rosuvastatin Calcium (2) · Simvastatin (2) · Tablets (2)
Emalex Biosciences Inc. (3) · Tabula Rasa HealthCare (3) · Cinclus Pharma Holding AB (2) · Hua Medicine Limited (2) · Pfizer (2) · Thai Red Cross AIDS Research Centre (2) · University of Buenos Aires (2) · University of Florida (2) · Ain Shams University (1) · Antios Therapeutics, Inc (1) · AstraZeneca (1) · Bayer (1) · Biogen (1) · Calithera Biosciences, Inc (1) · Chinese University of Hong Kong (1)
United States (16) · China (4) · Sweden (4) · Canada (3) · Germany (3) · Argentina (2) · Australia (2) · Egypt (2) · France (2) · Italy (2) · Nigeria (2) · South Korea (2) · Thailand (2) · Belgium (1) · Botswana (1)
Veronique Michaud (2) · Babatunde A Adeagbo, PhD (1) · Carolyn L Westhoff, MD (1) · Dolly Parasrampuria, PhD (1) · Dominick J Angiolillo, MD, PhD (1) · Emma Foreman (1) · Francisco Azzato, MD PhD (1)
PMID 10103341, PMID 10586010, PMID 11981287, PMID 15255031, PMID 16374442, PMID 16816511, PMID 17036033, PMID 20368313, PMID 20836739, PMID 20858862, PMID 21178824, PMID 21496529, PMID 21521834, PMID 21636639, PMID 21646940, PMID 21784446, PMID 21809002, PMID 22206744, PMID 22424940, PMID 22532328, PMID 22875659, PMID 23149172, PMID 23224224, PMID 23592318, PMID 23669525, PMID 24022367, PMID 24168068, PMID 24296799, PMID 24607244, PMID 24623338, PMID 25155722, PMID 25280497, PMID 25808019, PMID 26169430, PMID 27486571, PMID 27490643, PMID 27943125, PMID 29732396, PMID 31761141, PMID 32106339, PMID 32138284, PMID 32481505, PMID 32818481, PMID 33755736, PMID 34866168, PMID 36045316, PMID 36214883, PMID 36752290, PMID 3761090, PMID 38860384
2015 (2), 2023 (1), UG1DA050207 (1)