Digestive System Diseases: Clinical Trials

1,774 trials for Digestive System Diseases, newest first

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1774 unknown. 1774 Phase 2, 298 Phase 1, 179 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 21774Unknown 1774
Phase 1298Unknown 298
Phase 3179Unknown 179

Follow Digestive System Diseases: new trials by email Literature Review of Digestive System Diseases trials Research Report on Digestive System Diseases

Trials (filtered) newest first · largest first

All 1,774 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Study to Evaluate the Immunogenicity of LR20062 Compared to Control When Administered Intramuscularly in Healthy Infants At 2, 4, 6 Months of Age
LR20062, DTaP-HepB-IPV-Hib vaccine - Diphtheria, Tetanus
Phase 2UnknownLG Chem3362024-10-022024-10-01
Efficacy and Safety of Parecoxib vs. Indomethacin in Preventing Post-ERCP Pancreatitis
Parecoxib Sodium, Indomethacin suppository - Pancreatitis, Acute, Cholangiopancreatography, Endoscopic Retrograde
Phase 2UnknownShanghai General Hospital, Shanghai Jiao Tong University School of Medicine1002024-10-012024-10-02
Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study
Node-Sparing Short-Course Radiotherapy Combined with CAPOX and Sintilimab, CAPOX Chemotherapy - Microsatellite Stable (MSS) Colon Cancer, Locally Advanced Colon Cancer
Phase 2UnknownSir Run Run Shaw Hospital1402024-10-012024-09-19
BTLA Inhibitor (JS004) Combined with Toripalimab and Chemotherapy in the Perioperative Treatment of Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
BTLA inhibitor (JS004), Toripalimab, Paclitaxel, Cisplatin - Esophageal Squamous Cell Carcinoma
Phase 2UnknownHenan Provincial People's Hospital202024-09-302024-09-19
Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics
Trimebutine, Lactobacillus rhamnosus, Placebo - Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders
Phase 1 / Phase 2UnknownUniversidad de Colima822024-09-012024-08-16
Beta-Hydroxybutyrate Feasibility Treating IBD
Feasibility of beta-hydroxybutyrate supplementation to reduce inflammation in patients with Crohn's - Crohn's Disease, Inflammatory Bowel Diseases
Phase 1 / Phase 2UnknownUniversity of Texas at Austin202024-08-282024-09-19
A Study of Camrelizumab Plus Apatinib as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Radical Resection or Ablation
Camrelizumab, Apatinib - Hepatocellular Carcinoma
Phase 2UnknownZhujiang Hospital382024-08-262024-08-09
Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders
MTP-101P, Vancomycin, Miralax - Autism Spectrum Disorder, Gastro-Intestinal Disorder
Phase 2UnknownGut-Brain-Axis Therapeutics Inc.602024-08-202024-09-25
Modified FOLFOXIRI Plus Target Therapy as a First Line Treatment for Advanced Colorectal Cancer a Prospective Phase Two Study
FOLFOXIRI Protocol - Neoplasm Malignant, Colon Cancer Stage 4
Phase 2UnknownAl-Azhar University602024-08-172024-08-28
Phase 2a Study of Safety, Tolerability, and Efficacy of TLC-2716 in Subjects With Hypertriglyceridemia and NAFLD
TLC-2716 Dose 1, TLC-2716 Dose 2, Placebo - Hypertriglyceridemia, Nonalcoholic Fatty Liver Disease
Phase 2UnknownOrsoBio, Inc302024-08-122025-04-03
Exploratory Study of Irinotecan Liposomes in Maintenance Therapy of Metastatic Colorectal Cancer
Irinotecan Liposome, Bevacizumab - Metastatic Colorectal Cancer
Phase 1 / Phase 2UnknownWest China Hospital202024-08-092024-08-09
A Study on the Combination of Sintilimab, Ramucirumab and Chemotherapy for First-line Treatment of Gastric Cancer With Liver Metastasis
Sintilimab, Ramucirumab, SOX/XELOX - Stomach Neoplasms
Phase 2UnknownThe First Affiliated Hospital with Nanjing Medical University392024-08-012024-08-28
Cryoablation Combined With PD-1 Antibody and Bevacizumab for Hepatocellular Carcinoma
Cryoablation, PD-1 antibody and bevacizumab - Carcinoma, Hepatocellular
Phase 2UnknownShanghai Zhongshan Hospital362024-07-312024-07-31
Prospective Phase II Study on Continuous Circumferential Reinforcement of Laparoscopic Rectal Anastomosis to Prevent Complications
Continuous Circumferential Reinforcement of the Anastomotic - Colorectal Cancer, Anastomotic Leakage
Phase 2UnknownZHI-ZHONG PAN2082024-07-202024-07-11
HAIC Combined With TQB2450 and Anlotinib in Second-line Treatment of Advanced Hepatocellular Carcinoma
HAIC(Mitoxantrone+Raltitrexed)、anlotinib、TQB2450 - Hepatocellular Carcinoma
Phase 2UnknownFudan University422024-07-202024-06-26
MRD-Guided Consolidation Therapy Following Definitive Radiotherapy in Esophageal Cancer
PD-1 monoclonal antibody consolidation therapy - Esophageal Cancer
Phase 2UnknownCancer Institute and Hospital, Chinese Academy of Medical Sciences1022024-07-162024-08-06
Adebrelimab in Combination With Apatinib and Chemotherapy/Chemoradiotherapy in Immuno-experienced Second-line ESCC.
Adebrelimab, Apatinib, Investigator chosen chemotherapy (ICC) - Esophageal Cancer
Phase 2UnknownThe First Affiliated Hospital of Henan University of Science and Technology542024-07-152024-06-18
Trilaciclib Combined With Concurrent Chemoradiotherapy and Immunotherapy in the Treatment of Esophageal Cancer
Trilaciclib Injection [Cosela], Placebo - Esophageal Cancer
Phase 2UnknownThe First Affiliated Hospital with Nanjing Medical University602024-07-092024-08-26
Safety and Efficacy of Autologous Tumor-infiltrating Lymphocytes Therapy in Patients With Hepatocellular Carcinoma
Autologous Tumor-infiltrating Lymphocytes - Hepatocellular Carcinoma
Phase 1 / Phase 2UnknownBeijing 302 Hospital202024-07-012024-08-13
First-Line Treatment Induced With mFOLFOX6 and HLX04 Regimen, Following Combined With Serplulimab in MSS Initially Unresectable Metastatic Colorectal Cancer
mfolfox6 and hlx04 regimen and Serplulimab, mfolfox6 and hlx04 regimen - Efficacy, Self, Safety Issues
Phase 2UnknownSir Run Run Shaw Hospital722024-07-012024-07-09

Showing 20 of 1774. Sign in to see all of them.

Narrower conditions

Colorectal Neoplasms (324)  ·  Stomach Neoplasms (285)  ·  Carcinoma, Hepatocellular (241)  ·  Pancreatic Neoplasms (163)  ·  Rectal Neoplasms (123)  ·  Esophageal Neoplasms (121)  ·  Esophageal Squamous Cell Carcinoma (102)  ·  Colonic Neoplasms (90)  ·  Liver Neoplasms (53)  ·  Neoplasm Metastasis (48)  ·  Biliary Tract Neoplasms (40)  ·  Neoplasms (39)  ·  Liver Cirrhosis (35)  ·  Colitis, Ulcerative (33)  ·  Non-alcoholic Fatty Liver Disease (27)

Broader conditions

Neoplasms by Site (1389)  ·  Digestive System Neoplasms (1377)  ·  Neoplasms (1377)  ·  Gastrointestinal Diseases (1103)  ·  Gastrointestinal Neoplasms (922)  ·  Intestinal Diseases (589)  ·  Intestinal Neoplasms (475)  ·  Colonic Diseases (438)  ·  Rectal Diseases (438)  ·  Liver Diseases (437)  ·  Neoplasms by Histologic Type (419)  ·  Neoplasms, Glandular and Epithelial (394)  ·  Carcinoma (373)  ·  Stomach Diseases (301)

Interventions

Oxaliplatin (159)  ·  Capecitabine (124)  ·  Fluorouracil (111)  ·  Irinotecan (89)  ·  Leucovorin (73)  ·  Cisplatin (70)  ·  S 1 (combination) (70)  ·  apatinib (70)  ·  Paclitaxel (66)  ·  Bevacizumab (64)  ·  sintilimab (63)  ·  Gemcitabine (60)  ·  camrelizumab (57)  ·  Radiotherapy (51)  ·  Drug Therapy (50)

Sponsors

Fudan University (74)  ·  Sun Yat-sen University (73)  ·  Tianjin Medical University Cancer Institute and Hospital (39)  ·  Shanghai Zhongshan Hospital (27)  ·  Chinese Academy of Medical Sciences (26)  ·  Zhejiang Cancer Hospital (24)  ·  Peking University (19)  ·  National Cancer Center, Korea (18)  ·  Chinese PLA General Hospital (17)  ·  National Taiwan University Hospital (17)  ·  Second Affiliated Hospital, Zhejiang University, School of Medicine (17)  ·  The First Affiliated Hospital with Nanjing Medical University (17)  ·  Cancer Institute and Hospital, Chinese Academy of Medical Sciences (16)  ·  Samsung Medical Center (16)  ·  Yonsei University (16)

Countries

China (825)  ·  United States (145)  ·  South Korea (109)  ·  France (51)  ·  Taiwan (45)  ·  Netherlands (40)  ·  United Kingdom (40)  ·  Italy (39)  ·  Japan (35)  ·  Germany (34)  ·  Spain (32)  ·  Canada (31)  ·  Israel (27)  ·  Brazil (22)  ·  Singapore (20)

Top investigators

Feng Wang (5)  ·  Lin Shen, MD (5)  ·  Lin Shen, Professor (5)  ·  Wei Peng Yong, MRCP, MB ChB (5)  ·  Subrat K Acharya, DM (4)  ·  Cathy Hammerman, MD (3)  ·  Christophe Louvet, MD, PhD (3)  ·  Daiming Fan (3)  ·  Fuxiang Zhou, M.D. (3)  ·  Gang Jin, Doctor (3)  ·  Gao-Jun Teng, MD (3)  ·  Haitao Zhao, MD (3)  ·  Hui-Ju Ch'ang, M.D. (3)  ·  Jian Zhou (3)  ·  Jingdong Zhang (3)

Results publications

PMID 30642373, PMID 35623069, PMID 12049862, PMID 12540794, PMID 15273542, PMID 20516446, PMID 23547081, PMID 25447852, PMID 25514302, PMID 26313683, PMID 26755520, PMID 26884585, PMID 27480145, PMID 28434648, PMID 30348638, PMID 32306237, PMID 34725214, PMID 35219300, PMID 36657089, PMID 37981041, PMID 38421211, PMID 39863139, PMID 41379261, PMID 9146781, PMID 10089184, PMID 10091726, PMID 10400410, PMID 10615932, PMID 10744089, PMID 11091234, PMID 11223832, PMID 11231246, PMID 11239312, PMID 11247898, PMID 11248153, PMID 11251976, PMID 11289756, PMID 11413430, PMID 11419162, PMID 11491192, PMID 11574279, PMID 11712875, PMID 11754382, PMID 11813623, PMID 11896099, PMID 11914441, PMID 11981766, PMID 12091661, PMID 12187070, PMID 12196368

NIH funding

2016 (6), 2009 (5), 2018 (5), 2019 (5), 2008 (4), 2015 (4), P30CA015083 (4), 2014 (3), 2017 (3), 2005 (2), 2023 (2), K08HD052885 (1), M01RR000096 (1), P20CA252732 (1), P30CA168524 (1)