24 completed, 13 recruiting, 13 unknown, 2 active not recruiting. 24 Not applicable, 16 Phase 4, 7 Phase 3, 5 Phase 2, 1 Early Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexamethasone and Duration of Spinal Anesthesia Dexamethasone, Placebo - Dexamethasone, Spinal Anesthesia | Phase 4 | Recruiting | Holy Family Hospital, Pakistan | 110 | 2026-08-15 | 2026-09-15 |
| Liposomal Bupivacaine Plus Plain Bupivacaine Versus Dexamethasone Plus Plain Bupivacaine in the Supraclavicular Brachial Plexus Block in Patients With Risk Factors for Severe Acute Postoperative Pain 10ml 0.5% plain bupivacaine with 10ml 1.33% liposomal bupivacaine, 19ml 0.5% plain bupivacaine with 1ml (4mg) dexamethasone - Pain, Postoperative, Liposomal Bupivacaine | Phase 3 | Recruiting | The University of Hong Kong | 90 | 2026-08-04 | 2026-09-08 |
| Effect of Dexamethasone on Plasma Levels of Bupivacaine and Dexamethasone After a Single-injection Interscalene Nerve Block. administration of dexamethasone intravenously - Pain, Interscalene Blocks | Not applicable | Recruiting | Pontificia Universidad Catolica de Chile | 40 | 2026-05-19 | 2026-08-12 |
| Clinical Tolerance of an Intraparotid Injection of Bupivacaine, Combined With Dexamethasone, After Parotidectomy for Benign Tumor Intraparotid injection of bupivacaine/ dexamethasone - Parotid Neoplasm, Bupivacaine | Early Phase 1 | Recruiting | Centre Hospitalier Universitaire de Nīmes | 10 | 2026-05-18 | 2026-09-10 |
| Olanzapine Based Dexamethasone-sparing Regimen for Breast Cancer Patients With Metabolic-risk Factors Pantoprazole, olanzapine, Dexamethasone - Olanzapine, Breast Cancer | Not applicable | Recruiting | Alexandria University | 90 | 2026-05-10 | 2026-08-04 |
| Dosing of Steroids for Acute Asthma Given in the Emergency Department - a Pilot Randomised Feasibility Trial of Dexamethasone in Children dexamethasone oral - Acute Asthma, Dexamethasone | Phase 4 | Recruiting | Sheffield Children's NHS Foundation Trust | 104 | 2026-02-23 | 2026-04-23 |
| Dexamethasone, Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy Dexamethasone, Dexmedetomidine, Dexamethasone and dexmedetomidine - GIT Function, Cholecystectomy, Laparoscopic | Not applicable | Recruiting | Benha University | 160 | 2025-12-15 | 2026-07-20 |
| Intravenous Dexamethasone for Inducing Labor in Women With Term Pregnancy and Pre-Labour Rupture of Membranes Dexamethasone, Prostaglandin E1, Normal Saline - Rupture of Membranes Prior to Onset of Labor, Induction of Labor | Phase 4 | Completed | Nishtar Medical University | 60 | 2025-07-15 | 2026-03-31 |
| The Effects of Dexamethasone and Ibuprofen on Postoperative Analgesia in Patients Undergoing Hand and Forearm Surgery With Axillary Brachial Plexus Block IV Dexamethasone 8mg, iv ibuprofen - Axillary Block, Dexamethasone | Completed | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | 79 | 2025-05-01 | 2026-05-22 | |
| Dexamethasone Versus Metoclopramide for Prophylaxis of Nausea and Vomiting After Cataract Surgery 0.9% normal saline, Metoclopramide 10mg, Dexamethasone - Cataract, Dexamethasone | Not applicable | Completed | Alexandria University | 210 | 2025-05-01 | 2026-10-21 |
| Effect of Pre-medication With Anti-inflammatory Drugs(Ibuprofen and Dexamethasone)on Post-Endodontic Pain Anti-inflammatory drug (ibuprofen), Anti-inflammatory drug (dexamethsaone) - Post-endodontic Pain, Ibuprofen | Phase 2 | Recruiting | Armed Forces Institute of Dentistry, Pakistan | 130 | 2025-02-15 | 2025-05-20 |
| Dapagliflozin Versus Dexamethasone Role in Pre-operative Management of Non- Diabetic Brain Tumor Patients Dapagliflozin placebo, Placebo, DexamethasoneGroup III (n=25) (Dexamethasone group) - Glioma, Dapagliflozin (Forxiga) | Phase 3 | Completed | Tanta University | 75 | 2025-01-20 | 2026-09-30 |
| Adding Dexamethasone to Lidocaine in Scalp Incision Infiltration for Craniotomy Xylocaine plus Dexamethasone, Xylocaine plus epinephrine - Dexamethasone, Lidocaine | Not applicable | Completed | Assiut University | 100 | 2024-12-01 | 2026-08-26 |
| Dexmedetomidine Versus Dexamethasone as an Additive to Local Anesthetic Mixture in Peribulbar Block in Cataract Surgeries Dexmedetomidine, Dexamethasone, Normal saline - Dexmedetomidine, Dexamethasone | Not applicable | Completed | Helwan University | 75 | 2024-12-01 | 2026-06-26 |
| Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia Dexamethasone, Tocilizumab, Anakinra - Sepsis, Neuroinflammatory Response | Phase 4 | Unknown | Radboud University Medical Center | 52 | 2024-10-24 | 2025-04-04 |
| Effect of Dexamethasone Adjuvant in Combined Supraclavicular Block and Suprascapular Block Versus Interscalene Block in Patients Undergoing Shoulder Arthroscopy Shoulder arthroscopy blocks - Shoulder Arthroscopy Blocks, Dexamethasone | Not applicable | Recruiting | Assiut University | 60 | 2024-02-25 | 2025-04-22 |
| Dexamethasone and Dexmedetomidine Versus Dexmedetomidine Alone With Bupivacaine in Ultrasound Guided Rectus Sheath Block Dexmedetomidine and dexamethasone in addition to bupivacaine in rectus sheath block, dexamethsone in addition to bupivacaine in rectus sheath block - Dexmedetomidine, Dexamethasone | Not applicable | Active not recruiting | sarah mohamed | 40 | 2024-01-30 | 2025-04-24 |
| Effect of Adding Dexamethasone to Bupivacaine in Ultrasound-Guided Supraclavicular Brachial Plexus Blocks Versus Bupivacaine Alone for Upper Limb Orthopaedic Surgery Dexamethasone 8 mg - Dexamethasone, Bupivacaine | Completed | Arsi University | 54 | 2024-01-01 | 2026-02-10 | |
| Dexamethasone Versus Magnesium Sulphate as an Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block for Postoperative Analgesia in Elective Caesarean Section Under Spinal Anesthesia Bupivacaine, Dexamethasone, Magnesium sulphate - Dexamethasone, Magnesium Sulphate | Not applicable | Recruiting | Cairo University | 150 | 2023-12-01 | 2025-08-24 |
| Effect of Dexamethason on Postimplantation Syndrome After EVAR Dexamethasone, Placebo - Aneurysm Abdominal, Endovascular Aneurysm Repair | Phase 4 | Unknown | Centro Hospitalar de Lisboa Central | 158 | 2023-11-01 | 2023-09-21 |
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Pain, Postoperative (5) · Pain (3) · Postoperative Complications (3) · Agnosia (2) · Breast Neoplasms (2) · COVID-19 (2) · Carcinoma, Non-Small-Cell Lung (2) · Postoperative Nausea and Vomiting (2) · Aortic Aneurysm, Abdominal (1) · Cataract (1) · Chronic Pain (1) · Delirium (1) · Endotoxemia (1) · Fetal Membranes, Premature Rupture (1) · Glioblastoma (1)
Pathological Conditions, Signs and Symptoms (16) · Signs and Symptoms (12) · Neurologic Manifestations (11) · Neoplasms (10) · Pathologic Processes (9) · Neoplasms by Site (7) · Nervous System Diseases (6) · Respiratory Tract Diseases (6) · Lung Diseases (5) · Pain (5) · Infections (4) · Neoplasms by Histologic Type (4) · Postoperative Complications (4) · Neurobehavioral Manifestations (3) · Respiratory Tract Infections (3)
Dexamethasone (44) · Saline Solution (9) · Dexmedetomidine (6) · Bupivacaine (4) · Calcium Dobesilate (3) · Ropivacaine (3) · Sodium Chloride (3) · dexamethasone 21-phosphate (3) · Glucocorticoids (2) · Ibuprofen (2) · Magnesium Sulfate (2) · Metoclopramide (2) · flurbiprofen axetil (2) · Absorptiometry, Photon (1) · Adrenal Cortex Hormones (1)
Peking University First Hospital (4) · Assiut University (3) · Tanta University (3) · Alexandria University (2) · Beijing Tiantan Hospital (2) · Alborz Medical University (1) · Armed Forces Institute of Dentistry, Pakistan (1) · Arsi University (1) · Benha University (1) · Cairo University (1) · Centre Hospitalier Universitaire de Besancon (1) · Centre Hospitalier Universitaire de Nīmes (1) · Centro Hospitalar de Lisboa Central (1) · Copenhagen University Hospital, Rigshospitalet (1) · Eslam Ayman Mohamed Shawki (1)
Egypt (12) · China (11) · Canada (3) · Denmark (3) · Pakistan (3) · France (2) · Tunisia (2) · Turkey (Türkiye) (2) · Austria (1) · Chile (1) · Ethiopia (1) · Hong Kong (1) · Iran (1) · Malaysia (1) · Nepal (1)
Dong-Xin Wang, MD, PhD (3) · Allana Munro, MD FRCPC (1) · Andreas Raabe, MD (1) · Benjamin Lallemant (1) · Dong-xin Wang, Wang (1) · Jawad Zaheer, MBBS, FCPS (1) · Jianfeng Gong, MD (1) · Jinxiang Fu, M.D., PhD (1) · Judith Gilchrist (1)
PMID 19139429, PMID 25123271, PMID 33749741, PMID 34736497, PMID 35780235, PMID 36691030, PMID 37101983, PMID 37286048, PMID 37759444, PMID 38724526, PMID 40460271
2017 (1), 2019 (1), 2023 (1), 2025 (1)