13 completed. 13 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 13 | Completed 13 |
| Phase 2 | 4 | Completed 4 |
Follow Cross Infection: new trials by email Literature Review of Cross Infection trials Research Report on Cross Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Role of Acetyl Cysteine in Ventilator Associated Pneumonia by Carbapenem Resistance Klebsiella acetyl cysteine 600 mg, antibiotics and saline. - Ventilator Associated Pneumonia ( VAP), Mechanical Ventilation | Phase 1 | Completed | Tanta University | 70 | 2023-10-30 | 2025-07-31 |
| Red Light Photobiomodulation and Topical Disinfectants Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate - Healthcare Associated Infection, Nosocomial Infection | Phase 1 / Phase 2 | Completed | Ondine Biomedical Inc. | 28 | 2023-01-10 | 2023-04-04 |
| Nebulised BromAc in Healthy Volunteers BromAc - COVID-19 Pneumonia, Bromelains Adverse Reaction | Phase 1 | Completed | Mucpharm Pty Ltd | 12 | 2022-07-27 | 2022-09-15 |
| Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036) Ceftolozane/Tazobactam - Nosocomial Pneumonia | Phase 1 | Completed | Merck Sharp & Dohme LLC | 41 | 2020-04-17 | 2025-09-22 |
| Coated Devices to Decrease Infection in the Intensive Care Unit Coated devices, Control - Critically Ill | Phase 1 / Phase 2 | Completed | Hospital do Coracao | 103 | 2019-04-06 | 2020-03-09 |
| An Open Study to Assess the Safety and Pharmacokinetics of Fluorothyazinone as a Single-Dose Administration or a Treatment Course in Healthy Volunteers Fluorothyazinone 300 mg, Fluorothyazinone 600 mg, Fluorothyazinone 3900 mg - Healthy Volunteer | Phase 1 | Completed | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 25 | 2017-08-10 | 2018-07-24 |
| A Pharmacokinetic-pharmacodynamic Dose Comparison Study of 8 mg/kg of Inhaled or Parenteral Gentamicin in 12 Mechanically Ventilated Critically Ill Patients Treated for Ventilator-associated Pneumonia gentamicin - Ventilator-associated Pneumonia | Phase 1 | Completed | Poitiers University Hospital | 12 | 2015-10-01 | 2017-03-24 |
| Targeting Platelet-Leukocyte Aggregates in Pneumonia With Ticagrelor ticagrelor, placebo - Pneumonia, Community Acquired Pneumonia | Phase 1 | Completed | University of Kentucky | 60 | 2013-06-01 | 2018-09-13 |
| Optimization Dose Study on Pharmacokinetics and Pharmacodynamics of Colistin in Critically Ill Patients Colistin 6 million units + 240mg/8h, Colistin 6 million units + 360mg/12h - Critical Illness | Phase 1 | Completed | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 20 | 2011-10-01 | 2016-02-03 |
| Pilot Trial of KB001 in Mechanically-Ventilated Patients Colonized With Pseudomonas Aeruginosa KB001, Placebo - Pseudomonas Aeruginosa, Ventilator Associated Pneumonia | Phase 1 / Phase 2 | Completed | Humanigen, Inc. | 36 | 2008-04-01 | 2009-07-31 |
| Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa KBPA-101 - Pneumonia, Ventilator Associated Pneumonia | Phase 1 / Phase 2 | Completed | Kenta Biotech Ltd | 15 | 2008-02-01 | 2009-07-30 |
| Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections 2% chlorhexidine gluconate impregnated cloth, Daily bathing with Bar soap - Nosocomial Infection, Bacteremia | Phase 1 | Completed | Cook County Health | 208 | 2005-06-01 | 2023-06-18 |
| Oral Care Interventions and Ventilator Associated Pneumonia in Critically Ill Children 0.12% Chlorhexidine Digluconate, Toothbrushing - Ventilator Associated Pneumonia | Phase 1 | Completed | Federal University of São Paulo | 146 | 2005-06-01 | 2010-03-09 |
Pneumonia, Ventilator-Associated (7) · Pneumonia (5) · Healthcare-Associated Pneumonia (4) · Critical Illness (2) · Pseudomonas Infections (2) · Sepsis (2) · Acute Lung Injury (1) · Bacteremia (1) · Cellulitis (1) · Clostridium Infections (1) · Community-Acquired Pneumonia (1) · Infections (1) · Medullary cystic kidney disease 1 (1) · Persistent Infection (1)
Disease Attributes (13) · Iatrogenic Disease (13) · Pathologic Processes (13) · Pathological Conditions, Signs and Symptoms (13) · Infections (12) · Lung Diseases (11) · Respiratory Tract Diseases (11) · Respiratory Tract Infections (11) · Healthcare-Associated Pneumonia (6) · Pneumonia (6) · Bacterial Infections (3) · Bacterial Infections and Mycoses (3) · Inflammation (3) · Gram-Negative Bacterial Infections (2)
Acetylcysteine (1) · Anti-Bacterial Agents (1) · Gentamicins (1) · Soaps (1) · Sodium Chloride (1) · Ticagrelor (1) · Toothbrushing (1) · bromelain and acetylcysteine drug combination (1) · ceftolozane, tazobactam drug combination (1) · chlorhexidine gluconate (1) · colistinmethanesulfonic acid (1)
Cook County Health (1) · Federal University of São Paulo (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation (1) · Hospital do Coracao (1) · Humanigen, Inc. (1) · Kenta Biotech Ltd (1) · Merck Sharp & Dohme LLC (1) · Mucpharm Pty Ltd (1) · Ondine Biomedical Inc. (1) · Poitiers University Hospital (1) · Tanta University (1) · University of Kentucky (1)
United States (4) · France (2) · Russia (2) · Spain (2) · Australia (1) · Brazil (1) · Chile (1) · Colombia (1) · Egypt (1) · Estonia (1) · Greece (1) · Mexico (1) · Switzerland (1) · Ukraine (1)
Alexandre Biasi, MD/PhD (1) · Frank van Haren, MD, PhD (1) · Prof. Jean Chastre (1) · Robert A Weinstein, MD (1) · Susan S Smyth, MD PhD (1) · Violetta Georgescu (1) · Wessam Elfeky, Resident (1)
PMID 17954801, PMID 22497915, PMID 30175268, PMID 32526149
2018 (1)