21 completed, 9 unknown, 3 active not recruiting, 2 recruiting. 12 Not applicable, 4 Phase 4, 3 Phase 1, 3 Phase 3, 2 Phase 2.
Follow Persistent Infection: new trials by email Literature Review of Persistent Infection trials Research Report on Persistent Infection
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| NWRD09 for Persistent Cervical HPV16 Infection NWRD09/ Placebo administered by IM injection - Persistent Cervical HPV16 Infection | Not applicable | Recruiting | Newish Biotech (Wuxi) Co., Ltd. | 60 | 2026-02-10 | 2026-07-17 |
| Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles - Pain, Postoperative, Root Resorption | Not applicable | Enrolling by invitation | Ain Shams University | 108 | 2025-07-01 | 2026-09-29 |
| A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis CMTX-101, Placebo - Persistent Infection, Cystic Fibrosis | Phase 1 / Phase 2 | Completed | Clarametyx Biosciences, Inc. | 43 | 2024-06-24 | 2026-05-05 |
| Long-term Effectiveness and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Preadolescent Girls Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli), No intervention - Cervical Intraepithelial Neoplasia, Cervical Cancer | Active not recruiting | Xiamen University | 2188 | 2024-02-20 | 2025-07-31 | |
| Susceptibility to Infectious Diseases in Obesity Observational - Obesity, Type2diabetes | Recruiting | Azienda Ospedaliero Universitaria Maggiore della Carita | 80 | 2023-10-01 | 2026-09-10 | |
| CHILD (Child Health and Infection With Low Density) Malaria Active case detection using molecular testing (ACDm), Passive case detection using molecular testing (PCDm), Control (standard of care) - Malaria,Falciparum, Malaria | Not applicable | Completed | University of California, San Francisco | 600 | 2023-07-18 | 2026-01-29 |
| New Strategies for Assessment of the Persistence of Viable Bacilli in Latent and Active Tuberculosis Latent Tuberculosis, Persistent Infection | Completed | Region Skane | 89 | 2021-12-21 | 2026-09-29 | |
| Single-stage Surgery With Antibiotic-loaded Hydrogel Coated Implants Versus Two Stage Surgery for Secondary Prevention of Complex Chronic Periprosthetic Hip Joint Infection Defensive Antiadhesive Coating DAC®, Novagenit SRL - Hip Prosthesis Infection | Not applicable | Active not recruiting | Centre Hospitalier Universitaire de Saint Etienne | 39 | 2021-09-30 | 2026-05-06 |
| The Durability of Protection and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli) - Cervical Intraepithelial Neoplasia, Cervical Cancer | Unknown | Jun Zhang | 1339 | 2021-04-13 | 2023-01-26 | |
| Relationships Among Inflammation, Physical and Mental Health in Subjects With Chronic Inflammatory Physical Diseases. Chronic Infectious Disease, Chronic Skin Disease | Completed | University of Campania Luigi Vanvitelli | 93 | 2021-04-01 | 2023-11-22 | |
| The Durability of Protection Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli) - Cervical Intraepithelial Neoplasia, Cervical Cancer | Unknown | Jun Zhang | 647 | 2021-03-30 | 2023-01-26 | |
| Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m) Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli) - Cervical Intraepithelial Neoplasia, Cervical Cancer | Unknown | Jun Zhang | 979 | 2021-02-06 | 2023-01-26 | |
| Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli) / Cecolin® - Cervical Intraepithelial Neoplasia, Cervical Cancer | Phase 4 | Completed | Xiamen Innovax Biotech Co., Ltd | 540 | 2020-05-01 | 2022-06-29 |
| The Effectiveness of Hyperpure Chlorine Dioxide and Sodium Hypochlorite Irrigants in Endodontic Retreament in RCT endodontic desinfection - Persistent Infection, Periapical Lesion | Unknown | Eniko Vaszine Szabo | 40 | 2019-11-15 | 2022-10-31 | |
| Clinical Post-operative Assessment of Chronic Signs & Symptoms Related to Infected Primary Molars After Using Rotary Versus Manual Systems in Cleaning the Root Canals Rotary files - Chronic Infection | Not applicable | Unknown | Cairo University | 50 | 2018-10-01 | 2018-09-26 |
| Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission Tenofovir Disoproxil Fumarate (TDF) 300 mg oral daily. - Hepatitis B Infection, Congenital Malformation | Phase 4 | Unknown | New Discovery LLC | 280 | 2018-06-10 | 2019-12-12 |
| Cost-effectiveness Evaluation of One Stage Versus Two Stage Exchange for Chronically Infected Total Hip and Total Knee Prostheses Exchange of total hip or knee arthroplasty on same time, Exchange of total hip or knee arthroplasty in two time - Chronically Infected Total Hip of Knee Prosthesis | Not applicable | Unknown | University Hospital, Strasbourg, France | 100 | 2018-05-03 | 2018-05-22 |
| Prognostic Impact of Delta-haemolysin Production Deficiency in Staphylococcus Aureus on the Prognosis of Infected Implant Treated by DAIR Delta-haemolysin - Bone and Joint Infection, Staphylococcus Aureus | Unknown | Hospices Civils de Lyon | 100 | 2018-01-01 | 2023-04-13 | |
| Role of the Host Immunity in the Non-response to Direct Anti-viral Agent (DAA) Therapy blood drawing - Chronic Hepatitis C | Not applicable | Completed | Azienda Ospedaliero-Universitaria di Parma | 77 | 2017-08-30 | 2021-07-21 |
| An Open Study to Assess the Safety and Pharmacokinetics of Fluorothyazinone as a Single-Dose Administration or a Treatment Course in Healthy Volunteers Fluorothyazinone 300 mg, Fluorothyazinone 600 mg, Fluorothyazinone 3900 mg - Healthy Volunteer | Phase 1 | Completed | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 25 | 2017-08-10 | 2018-07-24 |
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Uterine Cervical Dysplasia (9) · Uterine Cervical Neoplasms (8) · Hepatitis B (3) · Viremia (3) · HIV Infections (2) · Hepatitis C, Chronic (2) · Abortion, Habitual (1) · Abortion, Spontaneous (1) · Acquired Immunodeficiency Syndrome (1) · Adenoviridae Infections (1) · Asymptomatic Infections (1) · Bronchiectasis (1) · Chronic Disease (1) · Common Cold (1)
Disease Attributes (36) · Infections (36) · Pathologic Processes (36) · Pathological Conditions, Signs and Symptoms (36) · Urogenital Diseases (13) · Genital Diseases (12) · Virus Diseases (11) · Communicable Diseases (10) · Female Urogenital Diseases and Pregnancy Complications (10) · Neoplasms (10) · Blood-Borne Infections (9) · Female Urogenital Diseases (9) · Genital Diseases, Female (9) · Neoplasms by Site (9) · Precancerous Conditions (9)
Vaccines (5) · Tenofovir (2) · Arthroplasty, Replacement, Knee (1) · Auranofin (1) · Blood Specimen Collection (1) · Ciprofloxacin (1) · Hepatitis B Vaccines (1) · Lamivudine (1) · Maraviroc (1) · Niacinamide (1) · Papillomavirus Vaccines (1) · Propylene Glycol (1) · Sodium Hypochlorite (1) · Standard of Care (1) · Telbivudine (1)
Jun Zhang (5) · New Discovery LLC (2) · Xiamen University (2) · Ain Shams University (1) · Azienda Ospedaliero Universitaria Maggiore della Carita (1) · Azienda Ospedaliero-Universitaria di Parma (1) · Cairo University (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Clarametyx Biosciences, Inc. (1) · Eniko Vaszine Szabo (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Federal University of São Paulo (1) · Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation (1) · Hospices Civils de Lyon (1) · Hua Zhang (1)
China (12) · France (4) · Italy (4) · United States (3) · Brazil (2) · Denmark (1) · Egypt (1) · Germany (1) · Hungary (1) · Israel (1) · Russia (1) · Sweden (1) · Tanzania (1) · United Kingdom (1)
Ting Wu, Ph. D. (6) · Calvin Q Pan, MD (2) · Erhei Dai, MD (2) · Yuemei Hu, Bachelor (2) · Ally Olotu, MD, PhD (1) · Amber D'Souza, PhD (1) · Carlo Ferrari, Dr (1) · David Gorard, Dr (1) · Eleanor Barnes, Dr. (1) · Guorong Han, MD (1)
PMID 25378645, PMID 27305192, PMID 31394172, PMID 31420362, PMID 33317695, PMID 33789963, PMID 35022035, PMID 36037823, PMID 37032449, PMID 38294704, PMID 38538037, PMID 39540799, PMID 39670565, PMID 39742565, PMID 40000087, PMID 41407728
2009 (1), R35DE026631 (1), U01AI155315 (1)