24 completed, 9 recruiting, 9 unknown, 4 terminated. 37 Not applicable, 10 Phase 2, 3 Early Phase 1, 2 Phase 3, 1 Phase 1.
Follow Craving: new trials by email Literature Review of Craving trials Research Report on Craving
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology Continuum Depression, Anxiety | Not yet recruiting | National Institute of Mental Health (NIMH) | 420 | 2026-12-05 | 2026-10-30 | |
| Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving Cannabidiol (CBD), Placebo - Alcohol Use Disorder (AUD), Withdrawal From Addictive Substance; Detoxification | Phase 2 / Phase 3 | Recruiting | Johns Hopkins University | 105 | 2026-10-21 | 2026-11-03 |
| Closed-loop TMS for the Core Clinical Features of Methamphetamine Use Disorder Closed-loop TMS, Conventional TMS, Random TMS - Methamphetamine Use Disorder, Substance Use Disorder | Not applicable | Not yet recruiting | Shanghai Mental Health Center | 21 | 2026-10-01 | 2026-11-02 |
| Endotoxin Exposure to Examine the Role of Inflammation in Alcohol Use Endotoxin, Placebo saline - Alcohol Use Disorder, Inflammatory Response | Phase 2 | Not yet recruiting | University of California, Los Angeles | 64 | 2026-09-01 | 2026-08-28 |
| An Open Label Pilot Study Assessing the Impact of Chromium Picolinate Supplementation on Appetite and Cravings in Overweight Individuals Study Product - Overweight (BMI > 25), Appetite | Recruiting | Nutrition 21, Inc. | 138 | 2026-08-31 | 2026-11-02 | |
| Closed-loop TBS Targeting rPO for the Core Clinical Features of Methamphetamine Use Disorder Closed-loop Theta-Burst Stimulation (TBS) Targeting rPO - Methamphetamine Use Disorder, Substance Use Disorder | Not applicable | Active not recruiting | Shanghai Mental Health Center | 5 | 2026-08-05 | 2026-11-02 |
| Probenecid Administration for Alcohol Craving and Consumption Probenecid Oral Tablet, Placebo Oral Tablet - Alcohol Use Disorder (AUD), Alcohol Consumption | Phase 2 | Recruiting | Brown University | 120 | 2026-03-14 | 2026-03-17 |
| tDCS for Social Media Addiction Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (Sham tDCS) - Social Media Addiction, Craving to Use Social Media | Not applicable | Completed | Egas Moniz - Cooperativa de Ensino Superior, CRL | 61 | 2026-03-01 | 2026-11-04 |
| Examining the Effectiveness of Dynamic Visual Noise (DVN) for Reducing Alcohol Cravings and Consumption in College Students Dynamic Visual Noise (DVN), Static Visual Noise (SVN) - Craving, Alcohol Drinking | Not applicable | Recruiting | University of Wyoming | 62 | 2025-09-22 | 2025-12-29 |
| Advancing VR-based Attentional Bias as a Biomarker for Tobacco Use Disorder Varenicline Tartrate, Placebo - Nicotine Addiction, Craving | Early Phase 1 | Recruiting | University of California, San Diego | 200 | 2024-11-19 | 2026-03-16 |
| Postprandial Metabolic and Appetite Responses to Different Food Intake Sequences in Athletes Carbohydrate-last meal pattern, Carbohydrate-first meal pattern - Healthy, Nutrition, Healthy | Not applicable | Completed | Universidade do Porto | 14 | 2024-04-22 | 2024-12-24 |
| Using Neurofeedback to Understand the Relationship Between Stress and Alcohol Consumption ScanSTRESS fMRI-paradigm (Streit et al., 2014), real-time fMRI neurofeedback - Alcohol Abuse, Craving | Not applicable | Recruiting | Central Institute of Mental Health, Mannheim | 102 | 2024-03-01 | 2025-01-23 |
| Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder Trier Social Stress Test, Barlab Cue-Exposure, Functional magnetic resonance imaging - Alcohol Use Disorder, Stress Reaction | Not applicable | Recruiting | Central Institute of Mental Health, Mannheim | 100 | 2023-12-01 | 2025-04-29 |
| A Single Session Self-guided Acceptance-based Digital Intervention Targeting Food Cravings in Pregnancy Single-session acceptance-based online workshop targeting food cravings as predictors of loss of control and binge eating in pregnancy - Pregnancy Weight Gain, Eating Disorders | Not applicable | Unknown | University at Albany | 130 | 2023-11-15 | 2023-11-13 |
| Gut Health and the Effect on Substance and Alcohol Cravings probiotic and pickle - Craving | Early Phase 1 | Unknown | City Rescue Mission Medical Clinic | 30 | 2023-09-01 | 2023-09-07 |
| State-dependent Interoception, Value-based Decision-making, and Introspection Pain, Stress, Craving - Stress, Pain | Not applicable | Recruiting | National Institute of Mental Health (NIMH) | 900 | 2023-07-25 | 2026-10-02 |
| Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder Smartphone - Opioid-Related Disorders, Mobile Applications | Not applicable | Enrolling by invitation | University of Arkansas | 336 | 2023-05-16 | 2026-05-15 |
| Electroencephalographic Biofeedback Therapy in Heroin Craving Pharmacological in addition to electroencephalographic (EEG) biofeedback, Pharmacotherapy - Electroencephalographic, Biofeedback Therapy | Not applicable | Completed | Tanta University | 40 | 2023-02-01 | 2025-02-21 |
| Non-invasive Brain Stimulation in Patients With Methamphetamine Use Disorder Intermittent theta burst transcranial magnetic stimulation (iTBS), Sham stimulation - Craving, Depression, Anxiety | Not applicable | Unknown | National Taiwan University Hospital Hsin-Chu Branch | 60 | 2022-09-01 | 2022-09-10 |
| Neurofeedback Based on Near-infrared Spectroscopy as a Therapy for Food Addiction in Obese Subjects. Sham, NF - Obesity, Craving | Not applicable | Recruiting | Rennes University Hospital | 50 | 2022-05-25 | 2025-08-08 |
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Alcoholism (11) · Behavior, Addictive (9) · Alcohol Drinking (5) · Obesity (5) · Opioid-Related Disorders (5) · Anxiety Disorders (4) · Cigarette Smoking (4) · Depression (4) · Fractures, Stress (4) · Smoking (4) · Smoking Cessation (4) · Substance-Related Disorders (4) · Tobacco Use Disorder (4) · Amphetamine-Related Disorders (2) · Emotional Regulation (2)
Mental Disorders (31) · Behavior (27) · Chemically-Induced Disorders (25) · Substance-Related Disorders (21) · Pathological Conditions, Signs and Symptoms (16) · Signs and Symptoms (13) · Alcohol-Related Disorders (11) · Compulsive Behavior (10) · Impulsive Behavior (10) · Body Weight (8) · Nutritional and Metabolic Diseases (7) · Drinking Behavior (6) · Nutrition Disorders (6) · Overnutrition (6) · Behavioral Symptoms (5)
Psychological Tests (3) · Transcranial Magnetic Stimulation (3) · Endotoxins (2) · Sodium Chloride (2) · Transcranial Direct Current Stimulation (2) · Varenicline (2) · salicylhydroxamic acid (2) · AT2G25170 protein, Arabidopsis (1) · Ashwagandha (1) · Biofeedback, Psychology (1) · Cannabidiol (1) · Cognitive Behavioral Therapy (1) · Control Groups (1) · Drug Therapy (1) · Exercise (1)
Central Institute of Mental Health, Mannheim (4) · Medical University of South Carolina (3) · University of California, Los Angeles (3) · Centre for Addiction and Mental Health (2) · National Institute of Mental Health (NIMH) (2) · Shanghai Mental Health Center (2) · University Hospital, Bordeaux (2) · University of Pittsburgh (2) · Wake Forest University Health Sciences (2) · BrightView LLC (1) · Brown University (1) · Butler Hospital (1) · Centre Hospitalier Intercommunal Creteil (1) · Centre Hospitalier St Anne (1) · City Rescue Mission Medical Clinic (1)
United States (27) · France (6) · Germany (4) · Brazil (2) · China (2) · Portugal (2) · Switzerland (2) · Canada (1) · Egypt (1) · Taiwan (1)
Lara Ray, PhD (2) · Silvia Lopez Guzman, M.D. (2) · Ana M Abrantes, Ph.D. (1) · Andrew James, Ph.D. (1) · Anna McCarthy, MD MPH (1) · Bettina Winzeler, Dr. (1) · Cara C Young, Ph.D. (1) · Carolina Haass-Koffler, PharmD, PhD (1) · Chen Cheng-Che, MD,MSc (1) · Cheng-Che Chen, MD, MSc (1) · Chloe Lucet, PH (1) · Clemens Kirschbaum, PhD (1) · Colleen A Hanlon, PhD (1) · David Woliinsky, MD (1)
PMID 20189549, PMID 22369958, PMID 22464727, PMID 26275843, PMID 29486960, PMID 35953259, PMID 35984870, PMID 35984871, PMID 36824884, PMID 36874396, PMID 37016394, PMID 37081574, PMID 37991022, PMID 38264360, PMID 38371479, PMID 38537903, PMID 38789642, PMID 40037282, PMID 40148844, PMID 41214823, PMID 42435898, PMID 42617805
2017 (1), K01AA026005 (1), K23DK117994 (1), K24AA025704 (1), R01AA027705 (1), R01AT010896 (1), R01DA058665 (1), R21DA049539 (1), R44DA049616 (1), UG3DA047793 (1)