5 completed, 5 recruiting. 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 1 | Completed 1 |
Follow Corticobasal Degeneration (CBD): new trials by email Literature Review of Corticobasal Degeneration (CBD) trials Research Report on Corticobasal Degeneration (CBD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multi-Center Study of Natural History in Atypical Parkinsonian Syndromes (MAPS-NH) We did not apply any interventions; only observational research was conducted. - Multiple System Atrophy, Dementia With Lewy Bodies (DLB) | Recruiting | Second Affiliated Hospital of Soochow University | 500 | 2025-11-12 | 2026-09-08 | |
| Imaging Studies in Corticobasal Syndrome C-11 ER176 Radiotracer, C-11 PiB, AV1451 Tau - Cortico Basal Degeneration, Corticobasal Syndrome | Recruiting | Jennifer Whitwell | 80 | 2025-06-25 | 2026-07-14 | |
| The CurePSP Genetics Program Whole genome sequencing will be performed at the NIH - PSP, PSP - Progressive Supranuclear Palsy | Recruiting | Massachusetts General Hospital | 1000 | 2024-10-08 | 2026-01-14 | |
| AI-Enhanced Optimization of Acute Levodopa Challenge Test video recording - Vascular Parkinsonism, Drug-induced Parkinsonism | Recruiting | Beijing Tiantan Hospital | 2000 | 2024-05-28 | 2025-04-29 | |
| ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) Frontotemporal Lobar Degeneration (FTLD), Progressive Supranuclear Palsy (PSP) | Recruiting | Mayo Clinic | 2100 | 2020-03-01 | 2026-10-07 | |
| Human CNS Tau Kinetics in Tauopathies 13C6 Leucine - Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD) | Completed | Washington University School of Medicine | 27 | 2017-08-21 | 2022-04-13 | |
| ADDIA Proof-of-Performance Clinical Study volumetric MRI - Alzheimer Disease (AD), Frontotemporal Lobar Degeneration | Completed | Amoneta Diagnostics SAS | 821 | 2016-09-01 | 2024-09-19 | |
| 4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2 Observational Study - Corticobasal Degeneration (CBD), Corticobasal Syndrome (CBS) | Completed | University of California, San Francisco | 293 | 2016-01-01 | 2025-04-13 | |
| Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) FTLD, Progressive Supranuclear Palsy (PSP) | Completed | University of California, San Francisco | 1489 | 2014-09-01 | 2021-05-21 | |
| Safety Study of TPI-287 to Treat CBS and PSP TPI 287 2 mg/m2, TPI-287 20 mg/m2, Placebo - Primary Four Repeat Tauopathies (4RT), Corticobasal Syndrome (CBS) | Phase 1 | Completed | University of California, San Francisco | 44 | 2014-05-01 | 2020-04-15 |
Corticobasal Degeneration (10) · Supranuclear Palsy, Progressive (9) · Color Vision Defects (3) · Frontotemporal Dementia (3) · Frontotemporal Lobar Degeneration (3) · Multiple System Atrophy (3) · Amyotrophic Lateral Sclerosis (2) · Lewy Body Disease (2) · Alzheimer Disease (1) · Frontotemporal Dementia With Motor Neuron Disease (1) · Multiple system atrophy (MSA) with orthostatic hypotension (1) · Nerve Degeneration (1) · Neurodegenerative Diseases (1) · Parkinson Disease (1) · Pick Disease of the Brain (1)
Eye Diseases (10) · Nervous System Diseases (10) · Neurologic Manifestations (10) · Pathological Conditions, Signs and Symptoms (10) · Signs and Symptoms (10) · Basal Ganglia Diseases (9) · Brain Diseases (9) · Central Nervous System Diseases (9) · Cranial Nerve Diseases (9) · Movement Disorders (9) · Neurodegenerative Diseases (9) · Ocular Motility Disorders (9) · Ophthalmoplegia (9) · Paralysis (9) · Tauopathies (9)
Observation (1) · TPI-287 (1) · Videotape Recording (1)
University of California, San Francisco (3) · Amoneta Diagnostics SAS (1) · Beijing Tiantan Hospital (1) · Jennifer Whitwell (1) · Massachusetts General Hospital (1) · Mayo Clinic (1) · Second Affiliated Hospital of Soochow University (1) · Washington University School of Medicine (1)
United States (7) · Canada (3) · China (2) · Belgium (1) · France (1) · Italy (1) · Switzerland (1) · Turkey (Türkiye) (1)
Adam Boxer, MD, PhD (2) · Adam L Boxer, MD, PhD (2) · Adrian Ivanoiu, MD (1) · Audrey Gabelle, MD (1) · Bradley Boeve, MD (1) · Bruno Dubois, MD (1) · Chunfeng Liu (1) · Eloi Magnin, MD (1) · Florence Pasquier, MD (1) · Frisoni Giovanni, MD (1) · Hakan Gurvit, MD (1) · Howie Rosen, MD (1) · Jean-Christophe Bier, MD (1)
PMID 35790423, PMID 31710340, PMID 33827960, PMID 35492244, PMID 38578117, PMID 38959435
R01AG038791 (1), R01AG087140 (1), U19AG063911 (1), U54NS092089 (1)