3 no longer available, 2 completed, 2 unknown, 1 enrolling by invitation. 5 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Unknown 2, Terminated 1 |
| Not applicable | 1 | Enrolling by invitation 1 |
Follow HBOC 201: new trials by email Literature Review of HBOC 201 trials Research Report on HBOC 201
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Expanded Access Study of HBOC-201 (Hemopure) for the Treatment of Life-Threatening Anemia HBOC-201 - Anemia | Not applicable | Enrolling by invitation | Englewood Hospital and Medical Center | 50 | 2013-10-01 | 2025-04-13 |
| Hemoglobin Based Oxygen Therapeutics in Elective Percutaneous Coronary Revascularization Hemoglobin Based Oxygen Carrier-201 (HBOC-201, Hemopure) - Coronary Occlusion, Acute Coronary Syndrome | Phase 2 | Completed | Biopure Corporation | 5 | 2007-04-01 | 2008-05-30 |
| Safety/Feasibility Study of HBOC-201 in Amputation at/Below Knee From Critical Lower Limb Ischemia Hemoglobin glutamer 250 - bovine, 6% Hydroxyethylstarch - Peripheral Vascular Disease | Phase 2 | Terminated | Biopure Corporation | 16 | 2006-05-01 | 2008-05-16 |
| A Study of Hemopure® to Enhance Tissue Preservation During Cardiopulmonary Bypass Surgery HBOC-201 (hemoglobin glutamer-250 bovine) - Coronary Artery Disease | Phase 2 | Unknown | Biopure Corporation | 60 | 2006-02-01 | 2008-05-16 |
| A Single Site Safety and Tolerability Study of HBOC-201 in Trauma Subjects Hemoglobin-based oxygen carrier-201 (HBOC 201), Standard of Care - Wounds and Injuries | Phase 2 | Unknown | Biopure Corporation | 53 | 2004-07-01 | 2008-03-06 |
| Pilot Study of Hemoglobin Based Oxygen Therapeutics in Elective Coronary Revascularization Percutaneous Coronary Revascularization, Hemoglobin-Based Oxygen Carrier-201 (HBOC-201), Voluven - Angina Pectoris, Unstable Angina | Phase 2 | Completed | Biopure Corporation | 45 | 2003-12-01 | 2008-05-16 |
| Expanded Access IND Administration of HBOC-201 in Patients With Severe Acute Anemia HBOC-201 - Anemia Severe | No longer available | Michael Boisen | 2026-07-20 | |||
| HBOC-201 Expanded Access Protocol for Life-threatening Anemia for Whom Allogeneic Blood Transfusion is Not an Option HBOC-201 - Anemia | No longer available | Mauricio Lynn | 2024-12-20 | |||
| Expanded Access Protocol Using HBOC-201 HBOC-201 - Anemia | No longer available | Johns Hopkins University | 2025-10-23 |
Anemia (3) · Acute Coronary Syndrome (1) · Angina Pectoris (1) · Angina, Unstable (1) · Chronic Limb-Threatening Ischemia (1) · Coronary Artery Disease (1) · Coronary Occlusion (1) · Hematologic Diseases (1) · Multiple Trauma (1) · Myocardial Infarction (1) · Myocardial Ischemia (1) · Peripheral Vascular Diseases (1) · Wounds and Injuries (1) · Wounds, Gunshot (1) · Wounds, Nonpenetrating (1)
Biopure Corporation (5) · Englewood Hospital and Medical Center (1) · Johns Hopkins University (1) · Mauricio Lynn (1) · Michael Boisen (1)
United States (4) · South Africa (3) · Netherlands (2) · United Kingdom (2) · Belgium (1) · Germany (1) · Greece (1)
A. Gerson Greenburg, MD, PhD (2) · A. Gerson Greenburg, MD, Ph.D (1) · A. Gerson Greenburg, MD, Ph.D. (1) · Carmine Gianatiempo, MD (1) · Mauricio Lynn (1) · P W Serruys, Professor (1) · Professor Ken D Boffard, MD (1) · Steven M Frank, MD (1)