12 completed, 9 recruiting, 8 unknown, 6 active not recruiting. 16 Not applicable, 5 Phase 4, 2 Phase 2, 1 Phase 1, 1 Phase 3.
Follow Coronary Microvascular Disease: new trials by email Literature Review of Coronary Microvascular Disease trials Research Report on Coronary Microvascular Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Microcirculatory Function in Type 2 Myocardial Infarction (T2MI) Coronary angiogram with coronary reactivity testing (CRT) - Myocardial Infarction, Coronary Microvascular Disease | Not yet recruiting | Mayo Clinic | 52 | 2027-01-01 | 2026-08-31 | |
| Coronary MicrovAscular Diseases Intervention With Compound Danshen Dropping Pills Compound Danshen Dripping Pills, Placebo - Coronary Microvascular Disease | Phase 4 | Not yet recruiting | Qilu Hospital of Shandong University | 496 | 2026-10-01 | 2026-10-21 |
| Coronary Sinus Reducer in Coronary Microvascular Disease Coronary sinus reducer, Sham CSR procedure - Angina (Stable), Coronary Microvascular Disease | Not applicable | Enrolling by invitation | UMC Utrecht | 50 | 2025-11-20 | 2025-12-04 |
| The FLARE (Flurpiridaz vs. Rubidium Evaluation) Trial Coronary Artery Disease, Coronary Microvascular Disease | Enrolling by invitation | University of California, Los Angeles | 60 | 2025-08-13 | 2026-08-17 | |
| Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG) Brenzavvy (bexagliflozin), 20 mg Oral Tablet, Placebo - Angina Patients With Non-obstructive Coronary Artery Disease, Coronary Microvascular Disease | Phase 1 | Recruiting | University of Virginia | 150 | 2025-07-15 | 2026-09-09 |
| Self-Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD) (SERRA-I Study) A-FLUX Reducer System - Coronary Microvascular Dysfunction, Coronary Microvascular Disease | Not applicable | Active not recruiting | VahatiCor, Inc. | 30 | 2025-06-18 | 2026-08-26 |
| Clinical Evaluation of Aromatic Wentong in the Treatment of Coronary Microvascular Disease Kuangxiong Aerosol, Placebo Drug - Coronary Microvascular Disease | Phase 4 | Not yet recruiting | China-Japan Friendship Hospital | 528 | 2025-04-01 | 2025-04-11 |
| An Observational Study of Coronary Microvascular Disease of China Coronary Microvascular Disease | Recruiting | Henan Institute of Cardiovascular Epidemiology | 500 | 2024-11-11 | 2025-08-20 | |
| Impact of Exercise Training on Ischemia With Non-Obstructive Coronary Arteries (INOCA): The ExINOCA Study Exercise training - Coronary Microvascular Disease, CMD | Not applicable | Recruiting | Bispebjerg Hospital | 100 | 2024-11-01 | 2025-02-21 |
| Insulin Resistance and Coronary Microvascular Dysfunction in Patients With Myocardial Ischemia and Non-obstructive Coronary Artery Disease Thermodilution based assessment of coronary microcirculation, Hyperinsulinemic-euglycemic Clamp test - Coronary Microvascular Dysfunction, Coronary Microvascular Disease | Not applicable | Active not recruiting | Azienda Ospedaliera Universitaria Integrata Verona | 40 | 2024-06-24 | 2026-10-27 |
| MCG as a Noninvasive Diagnostic Strategy for Suspected INOCA (MICRO2) CardioFlux - Ischemic Heart Disease, Coronary Microvascular Disease | Completed | Genetesis Inc. | 136 | 2024-06-03 | 2025-07-10 | |
| MCG for Suspected INOCA Confirmed by Thermodilution-Derived CFR CardioFlux Magnetocardiography - Ischemic Heart Disease, Coronary Microvascular Disease | Completed | Genetesis Inc. | 48 | 2023-12-20 | 2024-05-31 | |
| Qishenyiqi Dripping Pill for Coronary Microvascular Disease Qishenyiqi dripping pills 1 bag, three times a day, Placebo 1 bag, three times a day - Coronary Microvascular Disease | Phase 4 | Recruiting | Qilu Hospital of Shandong University | 162 | 2023-11-08 | 2024-11-21 |
| Multicenter Registry on Microvascular Dysfunction - Searching a New Ach Spasm Definition Coronary physiology assessment - Coronary Microvascular Disease, Coronary Vasospasm | Recruiting | Johannes Gutenberg University Mainz | 1000 | 2023-09-30 | 2024-11-01 | |
| Coronary Flow During Rapid Heart Rates Pressure and flow measurement during simulated VT - Ventricular Tachycardia, Coronary Artery Disease | Recruiting | Imperial College London | 70 | 2023-08-01 | 2026-03-27 | |
| Exercise and Coronary Microvascular Disease Cardiac rehabilitation - Coronary Microvascular Disease | Not applicable | Active not recruiting | CoreAalst BV | 204 | 2023-07-31 | 2026-01-20 |
| Serial PET MPI in Patients Undergoing Cancer Treatment Cancer, Chemotherapeutic Toxicity | Enrolling by invitation | University of California, Los Angeles | 60 | 2023-06-01 | 2025-08-06 | |
| A Clinical Study of Fundus OCTA for the Identification of CMD CaIMR - Coronary Microvascular Disease | Recruiting | Peking University First Hospital | 400 | 2023-03-01 | 2025-08-12 | |
| A Non-invasive Index of Microciculatory Resistance CCTA, CT-MPI, DSA, FFR - Coronary Microvascular Disease, Coronary Artery Disease | Not applicable | Completed | First People's Hospital of Hangzhou | 295 | 2022-12-15 | 2025-06-04 |
| Measuring Blood Flow in Heart Vessels With a New Fibre Optic Sensor Intra coronary rapid-exchange iKOs microcatheter intervention - Coronary Artery Disease, Coronary Stenosis | Not applicable | Completed | Queen Mary University of London | 10 | 2022-12-14 | 2024-04-30 |
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Microvascular Angina (44) · Angina Pectoris (9) · Coronary Artery Disease (7) · Myocardial Ischemia (7) · Myocardial Infarction (5) · Angina, Stable (2) · Heart Failure (2) · Anxiety Disorders (1) · Cardiovascular Diseases (1) · Chest Pain (1) · Coitus (1) · Coronary Stenosis (1) · Coronary Vasospasm (1) · Factor XIII Deficiency (1) · Hypertension (1)
Heart Diseases (44) · Vascular Diseases (44) · Cardiovascular Diseases (43) · Myocardial Ischemia (37) · Angina Pectoris (35) · Pathological Conditions, Signs and Symptoms (16) · Neurologic Manifestations (10) · Pain (10) · Signs and Symptoms (10) · Chest Pain (9) · Coronary Disease (8) · Arterial Occlusive Diseases (7) · Arteriosclerosis (7) · Pathologic Processes (7) · Infarction (6)
Adenosine (2) · Caloric Restriction (1) · Cardiac Rehabilitation (1) · Cardiotonic Agents (1) · Contrast Media (1) · Coronary Angiography (1) · Diet (1) · Dosage Forms (1) · Endurance Training (1) · Exercise (1) · Heparin (1) · Laser-Doppler Flowmetry (1) · Magnetic Resonance Imaging (1) · Myocardial Perfusion Imaging (1) · Pressure (1)
Qilu Hospital of Shandong University (4) · Bispebjerg Hospital (2) · CoreAalst BV (2) · Genetesis Inc. (2) · Johannes Gutenberg University Mainz (2) · Queen Mary University of London (2) · University Hospital, Grenoble (2) · University of California, Los Angeles (2) · University of Virginia (2) · AHEPA University Hospital (1) · Azienda Ospedaliera Universitaria Integrata Verona (1) · Cedars-Sinai Medical Center (1) · China-Japan Friendship Hospital (1) · First People's Hospital of Hangzhou (1) · Fundación EPIC (1)
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Eva Prescott, MD, DMSc (2) · Anthony Mathur (1) · Bo Zheng, Dr (1) · Claire Raphael, MBBS, PhD. (1) · Daniel Jones, MBBS, PhD (1) · Georgios Giannakoulas, MD, PhD (1) · Gilles Barone-Rochette (1) · Jamieson Bourque, BA,MD,MHS (1) · Jean-Paul Van Vooren, MD, PhD (1) · Joo Myung Lee, MD, MPH, PhD (1) · Josep Gomez Lara, MD PhD (1) · Kristen K Buck, MD (1) · Lijun Guo (1) · Nashwa Abdulsalam, MD (1) · Nathaniel Smilowitz, MD (1)
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K23HL119620 (1), R01HL124649 (1)