42 unknown. 42 Phase 1, 21 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 42 | Unknown 42 |
| Phase 2 | 21 | Unknown 21 |
Follow Congenital Abnormalities: new trials by email Literature Review of Congenital Abnormalities trials Research Report on Congenital Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Nasal Elevator Versus Grayson's Nasal Stent with D-NAM Appliance on Nasolabial Esthetics in Bilateral Cleft Lip and Palate Infants Nasal elevator with digital nasoalveolar molding in bilateral cleft lip and palate infants, Nasal stent with digital nasoalveolar molding in bilateral cleft lip and palate infants - Cleft Lip and Cleft Palate | Phase 1 | Unknown | Cairo University | 20 | 2024-11-01 | 2024-10-17 |
| BF844 Safety and Pharmacokinetic Study in Healthy Volunteers BF844 - Usher Syndrome Type 3 | Phase 1 | Unknown | EyeXCel Pty. Ltd. | 76 | 2024-09-09 | 2024-09-19 |
| Assessment of Therapeutic Effect of Rectal Vs. Intravenous Paracetamol in The Treatment of Patent Ductus Arteriosus (PDA) in Neonates Paracetamol - Patent Ductus Arteriosus | Phase 1 / Phase 2 | Unknown | Soha mahmoud Hussien mahdy | 100 | 2024-03-01 | 2024-02-13 |
| Fractional Co2 Laser Versus Microbotox Injection in the Treatment of Wide Facial Pores: A Split Face Comparative Study microbotox, fractional carbon dioxide laser - Skin Abnormalities | Phase 1 | Unknown | Assiut University | 21 | 2024-02-01 | 2023-12-27 |
| Evaluation of Antimicrobial Photodynamic Therapy and Minimal Intervention Associated With Deproteinization in Permanent Teeth With Molar Incisor Hypomineralization Antimicrobial PDT and Papacarie Deproteinization, Conventional caries treatment, Antimicrobial PDT and 5% NaOCl Deproteinization - Hypomineralization Molar Incisor | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 69 | 2023-08-20 | 2023-11-28 |
| Pazopanib for the Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia Pazopanib - Hereditary Hemorrhagic Telangiectasia, Epistaxis | Phase 1 / Phase 2 | Unknown | Cure HHT | 30 | 2023-07-01 | 2022-09-08 |
| Study of PTW-002 in Patients With Dominant or Recessive Dystrophic Epidermolysis Bullosa Due to Mutation(s) in Exon 73 of the COL7A1 Gene PTW-002 10 mg/g gel, Placebo - Dystrophic Epidermolysis Bullosa | Phase 1 / Phase 2 | Unknown | Phoenicis Therapeutics | 8 | 2023-04-30 | 2023-03-31 |
| A Study of BPI-452080 in Subjects With Solid Tumors BPI-452080 - Solid Tumor, Renal Cell Carcinoma | Phase 1 | Unknown | Betta Pharmaceuticals Co., Ltd. | 87 | 2023-04-28 | 2023-05-06 |
| BR790 in Combination With Anlotinib in Adult Subjects With Advanced Non-Small Cell Lung Cancer BR790+anlotinib - Non-Small Cell Lung Cancer | Phase 1 / Phase 2 | Unknown | Shanghai Gopherwood Biotech Co., Ltd. | 90 | 2023-02-01 | 2023-02-10 |
| Ketodex Versus Opioid Based Anaesthesia in Cleft Palate Repair Ketodex Versus Opioid Based Anaesthesia in Cleft Palate Repair Ketodex Versus Opioid Based Anaesthesia in Cleft Palate Repair Ketodex Versus Opioids in Cleft Palate Repaire Ketodex, Fentanyl - Ketodex Versus Opioids Based Anaesthesia in Cleft Palate Repair | Phase 1 | Unknown | Ain Shams University | 50 | 2022-02-01 | 2022-06-02 |
| Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery Dexrazoxane - Heart Defects, Congenital | Phase 1 | Unknown | University of Texas at Austin | 12 | 2021-04-09 | 2021-08-09 |
| Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction EB-CMF - Mandible Tumor, Mandibular Injuries | Phase 1 / Phase 2 | Unknown | Epibone, Inc. | 6 | 2021-03-31 | 2022-05-27 |
| Control of Pain Due to Dentin Hypersensitivity in Individuals With Molar-incisor Hypomineralization Hygiene Instructions, Sealant application, Low-level Laser - Dentin Sensitivity, Molar Incisor Hypomineralization | Phase 1 / Phase 2 | Unknown | University of Nove de Julho | 140 | 2021-01-01 | 2020-11-30 |
| Optimizing IV Gentamicin in JEB Gentamicin Sulfate, Injectable - Junctional Epidermolysis Bullosa | Phase 1 / Phase 2 | Unknown | University of Southern California | 6 | 2019-10-31 | 2022-11-03 |
| Metformin in Patients With Fragile X Metformin, Placebo oral tablet - Fragile X Syndrome | Phase 1 / Phase 2 | Unknown | Rowan University | 40 | 2019-10-29 | 2019-10-31 |
| Single Ascending Dose Study in Participants With LCA10 EDIT-101 - Leber Congenital Amaurosis 10, Inherited Retinal Dystrophies | Phase 1 / Phase 2 | Unknown | Editas Medicine, Inc. | 34 | 2019-09-26 | 2022-12-05 |
| Antimicrobial Photodynamic Therapy on Teeth With Molar Incisor Hypomineralization aPDT, ART - Molar Incisor Hypomineralization | Phase 1 | Unknown | University of Nove de Julho | 48 | 2019-08-01 | 2019-04-05 |
| Autologous Umbilical Cord Blood Treatment of Neonate With CHD Autlogous UCB infusion - Congenital Heart Disease, Brain Injuries | Phase 1 / Phase 2 | Unknown | Sheba Medical Center | 60 | 2019-02-01 | 2021-01-20 |
| Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors RMC-4630 - Solid Tumors | Phase 1 | Unknown | Revolution Medicines, Inc. | 133 | 2018-09-28 | 2022-09-01 |
| Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) Gentamicin - Recessive Dystrophic Epidermolysis Bullosa | Phase 1 / Phase 2 | Unknown | University of Southern California | 9 | 2018-07-05 | 2022-11-03 |
Showing 20 of 42. Sign in to see all of them.
Epidermolysis Bullosa Dystrophica (4) · Heart Defects, Congenital (3) · Leukemia, Myeloid, Acute (3) · Molar Hypomineralization (3) · Carcinoma, Non-Small-Cell Lung (2) · Cleft Palate (2) · Hydrophthalmos (2) · Hyperandrogenism (2) · Leukemia (2) · Leukemia, Monocytic, Acute (2) · Leukemia, Myelomonocytic, Acute (2) · Neoplasms (2) · Noonan Syndrome (2) · Arteriovenous Malformations (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (42) · Cardiovascular Diseases (12) · Genetic Diseases, Inborn (12) · Pathological Conditions, Signs and Symptoms (11) · Cardiovascular Abnormalities (10) · Skin and Connective Tissue Diseases (10) · Nervous System Diseases (9) · Skin Diseases (9) · Stomatognathic Diseases (9) · Heart Diseases (8) · Neoplasms (8) · Signs and Symptoms (8) · Female Urogenital Diseases (7) · Female Urogenital Diseases and Pregnancy Complications (7)
Cytarabine (2) · Everolimus (2) · Gentamicins (2) · Metformin (2) · 68Ga-1,4,7-triazacyclononane-N,N',N''-triacetic acid (1) · Acetaminophen (1) · Botulinum Toxins, Type A (1) · Cardiac Surgical Procedures (1) · Clofarabine (1) · Daunorubicin (1) · Deep Brain Stimulation (1) · Dexrazoxane (1) · Endoscopic Mucosal Resection (1) · Fentanyl (1) · Flow Cytometry (1)
University of Nove de Julho (3) · Cairo University (2) · University of Southern California (2) · Ain Shams University (1) · Al-Azhar University (1) · Assiut University (1) · Baylor College of Medicine (1) · Betta Pharmaceuticals Co., Ltd. (1) · Boston Children's Hospital (1) · Cure HHT (1) · Dow University of Health Sciences (1) · Editas Medicine, Inc. (1) · Epibone, Inc. (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · EyeXCel Pty. Ltd. (1)
United States (14) · China (5) · Brazil (2) · Egypt (2) · France (2) · United Kingdom (2) · Australia (1) · Azerbaijan (1) · Belgium (1) · Croatia (1) · Iran (1) · Israel (1) · Italy (1) · Netherlands (1) · Pakistan (1)
Abd-Elmoneim Shawky Shams El-deen, MD (1) · Abdel-Wahab El-Okby, MD (1) · Ahmed Said Sayed Bayomy, MSc (1) · Bader F Zuberi, FCPS (1) · Baohui Han (1) · Benedict Tan, MBBS, FRACP (1) · Braden Kuo, MD (1) · Brian R Gastman, MD (1) · Christopher R McCartney, MD (1) · Clarissa Foy, NP (1) · Dalia A Ahmed, professor (1) · Daniel Tan Shao Weng (1) · David T. Woodley, MD (1) · Dinghua Yi, MD (1) · Dingwei Ye, Ph.D (1)
PMID 19217726, PMID 23771484, PMID 24329107, PMID 26951240, PMID 31574879, PMID 33497524, PMID 33692185, PMID 34629400, PMID 35234826, PMID 38101830, PMID 38709228, PMID 38987318, PMID 42164509
P50HD028934 (1), ZIAEB000073 (1)