1 active not recruiting, 1 completed, 1 recruiting, 1 unknown. 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comprehensive HHT Outcomes Registry of the United States (CHORUS) Hereditary Hemorrhagic Telangiectasia, Arteriovenous Malformations | Recruiting | Cure HHT | 10000 | 2023-11-13 | 2026-07-17 | |
| Pazopanib for the Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia Pazopanib - Hereditary Hemorrhagic Telangiectasia, Epistaxis | Phase 1 / Phase 2 | Unknown | Cure HHT | 30 | 2023-07-01 | 2022-09-08 |
| Effects of Pazopanib on Hereditary Hemorrhagic Telangiectasia Related Epistaxis and Anemia (Paz) Pazopanib, Placebo oral capsule - Hereditary Hemorrhagic Telangiectasia, Epistaxis | Phase 2 / Phase 3 | Completed | Cure HHT | 71 | 2023-05-08 | 2026-10-27 |
| CHORUS - Comprehensive HHT Outcomes Registry of the United States (Formerly OUR HHT Registry) Registry and Saliva sample - Hereditary Hemorrhagic Telangiectasia, HHT | Active not recruiting | Unity Health Toronto | 296 | 2018-11-01 | 2026-04-22 |
Telangiectasia, Hereditary Hemorrhagic (4) · Epistaxis (3) · Arteriovenous Malformations (2) · Anemia (1) · Gastrointestinal Hemorrhage (1) · Intracranial Arteriovenous Malformations (1) · Telangiectasis (1) · Vascular Malformations (1)
pazopanib (2) · Cellulose (1) · Registries (1)
United States (2) · Canada (1)
Cassi Friday, PhD (1) · James Gossage, MD (1) · Marie E Faughnan, MD (1) · Nolie Krock, MSc (1) · Raj Kasthuri, MD (1)