36 completed, 18 recruiting, 12 unknown, 4 active not recruiting. 76 Phase 2, 14 Phase 1, 9 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation tDCS - Aphasia, Broca's Aphasia | Phase 2 / Phase 3 | Recruiting | University of South Carolina | 130 | 2026-07-14 | 2026-07-21 |
| Addressing Treatment Nonresponders VAULT Phase 6 - Language Development Disorders | Phase 2 | Not yet recruiting | University of Arizona | 16 | 2026-06-01 | 2025-07-30 |
| Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined. Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol - Autism Spectrum Disorder, Autism | Phase 1 / Phase 2 | Enrolling by invitation | Black Tie Medical, Inc. | 50 | 2026-04-30 | 2026-04-27 |
| Lumateperone in the Treatment of Stuttering, Childhood Onset Fluency Disorder Lumateperone (ITI-007), Placebo Tablet or Capsule - Stuttering, Adult | Phase 2 | Recruiting | CSTrials Inc. | 24 | 2026-04-18 | 2026-07-29 |
| Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial Xylitol Chewing gum, Sorbitol chewing gum - Preterm Birth, Low Birthweight Neonate | Phase 2 / Phase 3 | Recruiting | University of Washington | 6000 | 2026-03-26 | 2026-09-10 |
| Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter Psilocybin, Speech therapy - Stuttering | Phase 2 | Not yet recruiting | NYU Langone Health | 25 | 2026-01-15 | 2025-12-22 |
| Exploratory Evaluation of the Digital Therapeutic Device Zenicom for Subacute Stroke Aphasia Zenicog, Conventional Speech Therapy - Aphasia, Stroke | Phase 2 | Recruiting | Seoul National University Bundang Hospital | 20 | 2025-12-10 | 2026-02-10 |
| Clinical Study of Neflamapimod in Patients With Primary Progressive Aphasia Neflamapimod, Placebo - Nonfluent Variant Primary Progressive Aphasia (nfvPPA) | Phase 2 | Active not recruiting | EIP Pharma Inc | 20 | 2025-10-02 | 2026-07-06 |
| Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST) Semantic Feature Analysis (traditional), Semantic Feature Analysis + Metacognitive Strategy Training - Aphasia, Aphasia Following Cerebral Infarction | Phase 2 | Recruiting | Teachers College, Columbia University | 40 | 2025-07-28 | 2026-06-25 |
| A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise, Placebo Drug With Engineered Sound - Central Auditory Processing Disorder, Hearing Impaired (Partially) | Phase 1 / Phase 2 | Recruiting | University of Colorado, Denver | 344 | 2025-03-31 | 2026-04-30 |
| Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia Transcranial Magnetic Stimulation (TMS), Speech-Language Therapy (SLT) - Aphasia, Stroke | Phase 2 | Recruiting | University of Pennsylvania | 24 | 2025-02-11 | 2026-03-05 |
| Generalization With AI Navigation Using StaRt AI-guided maintenance training with visual-acoustic biofeedback, Treatment as Usual (TAU) - Speech Sound Disorder | Phase 2 | Recruiting | New York University | 76 | 2024-12-18 | 2026-05-13 |
| Lateral Cord Magnetic Stimulation For Refractory Spastic Cerebral Palsy Magnetic Spinal Stimulation - Spastic Cerebral Palsy, Dysarthria | Phase 2 / Phase 3 | Unknown | Sociedad Argenttina de Neuromodulación | 20 | 2024-11-18 | 2023-11-21 |
| Communication Bridge 3 Study Communication Bridge™, Evidence-Based Impairment Focused - Primary Progressive Aphasia | Phase 2 | Recruiting | University of Chicago | 200 | 2024-08-23 | 2026-06-01 |
| Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders Zinc Acetate Dihydrate - GNAO1, Dystonia | Phase 2 | Completed | Children's University Hospital Cologne, Germany | 13 | 2024-08-02 | 2026-02-03 |
| Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia Transcranial Magnetic Stimulation (TMS), Modified Constraint Induced Language Therapy (mCILT) - Stroke, Aphasia | Phase 2 | Recruiting | University of Pennsylvania | 63 | 2024-08-01 | 2026-06-18 |
| Visual-acoustic Intervention With Service Delivery In-person and Via Telepractice Trial Visual-acoustic biofeedback - Speech Sound Disorder | Phase 2 | Recruiting | New York University | 76 | 2024-07-01 | 2025-06-25 |
| Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia Active tDCS + Language Therapy, Sham tDCS + Language Therapy - Primary Progressive Aphasia, Logopenic Progressive Aphasia | Phase 2 | Recruiting | Johns Hopkins University | 180 | 2024-02-13 | 2026-05-05 |
| Adaptive Trial Scheduling in Naming Treatment for Aphasia Adaptive Spacing Condition, High-Item Non-Adaptive Spacing Condition, Low-Item Non-Adaptive Spacing Condition - Aphasia, Stroke | Phase 2 | Recruiting | University of Pittsburgh | 32 | 2023-12-06 | 2025-12-11 |
| Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia Accuracy-maximized condition, Effort-maximized condition, Effort-accuracy balanced condition - Aphasia, Stroke | Phase 2 | Recruiting | University of Pittsburgh | 30 | 2023-11-27 | 2026-04-13 |
Showing 20 of 76. Sign in to see all of them.
Aphasia (24) · Stroke (17) · Learning Disabilities (11) · Language Disorders (9) · Aphasia, Primary Progressive (8) · Language Development Disorders (7) · Stuttering (7) · Autism Spectrum Disorder (6) · Dementia (5) · Dyslexia (5) · Frontotemporal Dementia (5) · Language (5) · Speech (5) · Speech Sound Disorder (5)
Pathological Conditions, Signs and Symptoms (71) · Signs and Symptoms (71) · Neurobehavioral Manifestations (70) · Neurologic Manifestations (70) · Nervous System Diseases (68) · Language Disorders (50) · Mental Disorders (39) · Speech Disorders (38) · Neurodevelopmental Disorders (35) · Brain Diseases (29) · Central Nervous System Diseases (28) · Cardiovascular Diseases (17) · Cerebrovascular Disorders (17) · Vascular Diseases (16)
Transcranial Direct Current Stimulation (5) · Leucovorin (3) · Speech Therapy (3) · Therapeutics (3) · Transcranial Magnetic Stimulation (2) · ecopipam (2) · Animal Assisted Therapy (1) · Anti-Inflammatory Agents (1) · BPN14770 (1) · Capsules (1) · Clemastine (1) · Commerce (1) · Escitalopram (1) · Famotidine (1) · Fecal Microbiota Transplantation (1)
Southwest Autism Research & Resource Center (3) · University of Pennsylvania (3) · Johns Hopkins University (2) · NYU Langone Health (2) · New York University (2) · University of Arizona (2) · University of Pittsburgh (2) · University of South Carolina (2) · University of Sydney (2) · Ain Shams University (1) · AviadoBio Ltd (1) · Barretos Cancer Hospital (1) · Black Tie Medical, Inc. (1) · CSTrials Inc. (1) · Charite University, Berlin, Germany (1)
United States (53) · Canada (7) · Germany (5) · Australia (3) · Italy (2) · Sweden (2) · United Kingdom (2) · Argentina (1) · Belgium (1) · Brazil (1) · Egypt (1) · Hong Kong (1) · India (1) · Malawi (1) · Netherlands (1)
H. Branch Coslett, MD (3) · Richard E Frye, MD, PhD (3) · Mary Alt, PhD (2) · William Evans, PhD (2) · Abhishek Datta, Ph.D (1) · Achim Klug, PhD (1) · Agnes Floeel, Prof MD (1) · Agnes Floel, MD (1) · Alessandro Martorana, MD, PhD (1) · Alexander A Ostanin, MD, PhD (1) · Alexandre Jacinto, MD (1) · Ann Kaiser, PhD (1) · Argye Hillis-Trupe, MD (1)
PMID 10917410, PMID 12849360, PMID 15026214, PMID 15212606, PMID 15328899, PMID 20075648, PMID 20145986, PMID 21636820, PMID 23106988, PMID 24434529, PMID 25267381, PMID 26547399, PMID 28738099, PMID 29357099, PMID 29954605, PMID 30128538, PMID 31369655, PMID 32878377, PMID 33642973, PMID 33643204, PMID 33927413, PMID 34941929, PMID 39871189, PMID 40277885, PMID 40762274, PMID 40809903, PMID 42161555, PMID 42542632
R01DC015642 (2), R01DC017476 (2), R01DC019325 (2), 2023 (1), P50DC014664 (1), R01AG055425 (1), R01AG075111 (1), R01DC007387 (1), R01DC007660 (1), R01DC016321 (1), R01DC016800 (1), R01DC020959 (1), R01HD088528 (1), R01HD089474 (1), R01HD119029 (1)