164 completed, 42 unknown, 29 recruiting, 11 terminated. 204 Not applicable, 7 Early Phase 1, 5 Phase 1, 5 Phase 2, 2 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Minocycline In Neurocognitive Outcomes - Sickle Cell Disease Minocycline, Placebo - Sickle Cell Disease, Cognitive Impairment | Phase 1 | Not yet recruiting | University of Cincinnati | 30 | 2026-12-01 | 2026-05-14 |
| Study of Low-intensity Focused Ultrasound Effects on Cognitive fMRI Signals Neuromodulation with low-intensity focused ultrasound - Cognitive Change | Not applicable | Not yet recruiting | Virginia Polytechnic Institute and State University | 80 | 2026-10-01 | 2025-12-09 |
| Integrating Systematic Data of Medicine to Explore the Solution for Healthy Aging (ISDHA) Phase 4 Sleep Disturbance, Cognitive Change | Recruiting | Chang Gung Memorial Hospital | 250 | 2026-09-15 | 2026-07-30 | |
| Early Cognitive Interventions in Digital Format for Cancer Survivors Computerized cognitive treatment, Virtual reality cognitive training - Cognitive Impairment, Cognitive Change | Not applicable | Recruiting | Biogipuzkoa Health Research Institute | 110 | 2026-06-08 | 2026-07-28 |
| Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty Postoperative Cognitive Dysfunction (POCD), Cognitive Change | Recruiting | Odense University Hospital | 48 | 2026-05-18 | 2026-06-22 | |
| The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia Brain Health PRO - Dementia Prevention, Subjective Cognitive Impairment | Not applicable | Recruiting | University of British Columbia | 700 | 2026-05-07 | 2026-05-19 |
| MEVA Cognitive Wellness Platform Study for Adults MEVA Cognitive Wellness Platform - Cognitive Wellness, Healthy Aging | Not yet recruiting | Mentage LLC | 100 | 2026-05-01 | 2026-05-20 | |
| Cognitive Impact of Neoadjuvant Chemotherapy for Gynecologic Cancers Patient Reported Outcomes Assessment, Cognitive and General Health Assessments - Ovarian Cancer, Cognitive Change | Recruiting | University of Wisconsin, Madison | 18 | 2026-04-28 | 2026-08-27 | |
| Executive Function Training for Children and Adolescents Nongamified N-back training, Gamified N-back training, Multiple Domain Training - Cognitive Change | Not applicable | Recruiting | Northeastern University | 780 | 2025-12-14 | 2025-12-23 |
| Impact of Indoor Overheating on Physiological Strain in Children Simulated exposure to indoor overheating - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-11-08 | 2026-04-23 |
| Heat Stress in Individuals With Schizophrenia Simulated exposure to indoor overheating - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-11-08 | 2026-04-23 |
| Suitability of a 26 °C Indoor Environment for Mitigating Heat Strain in Young Adults Simulated indoor temperature upper limit - Heat Stress, Physiological Stress | Not applicable | Recruiting | University of Ottawa | 10 | 2025-11-07 | 2026-06-16 |
| Surviving Daily Life Mobile Daily Diary - Stress, Cognitive Change | Recruiting | Thomas Jefferson University | 30 | 2025-10-02 | 2025-10-22 | |
| Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury Active Transcranial direct current stimulation, Sham Transcranial direct current stimulation - Traumatic Brain Injury, Word Finding Difficulty | Not applicable | Recruiting | Beth Israel Deaconess Medical Center | 24 | 2025-10-01 | 2025-10-21 |
| Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer Memantine, Placebo medication, Exercise Intervention - Breast Cancer, Locally Advanced Breast Cancer | Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 90 | 2025-08-19 | 2026-05-06 |
| Effects of Blood Pressure on Cognition and Cerebral Hemodynamics in PD Head-up tilt table - Parkinson Disease, Orthostatic Hypertension | Not applicable | Withdrawn | University of California, San Diego | 2025-08-15 | 2026-04-27 | |
| Cognitive Augmentation Via Multimodal Sensing and Auricular Neurostimulation Active Neurostimulation, Sham Stimulation - Healthy, Cognitive Change | Not applicable | Completed | OpenBCI | 45 | 2025-04-30 | 2026-04-06 |
| Effectiveness of Cognitive Training in Older and Younger Adults Visual and / or Auditory Cognitive Tasks (1), Visual and / or Auditory Cognitive Tasks (2) - Cognitive Change | Not applicable | Recruiting | University of Wisconsin, Madison | 1600 | 2025-04-01 | 2026-05-29 |
| Cognition After OSA Treatment Among Native American People (CATNAP) CATNAP MI - Obstructive Sleep Apnea, Cognitive Change | Not applicable | Recruiting | Washington State University | 140 | 2025-02-06 | 2026-01-09 |
| Effects of Indena's Virtiva® Plus Ginkgo Biloba Extract on Stress, and Cognitive Performance Low Dose Virtiva Plus, High Dose Virtiva Plus - Stress, Mood | Not applicable | Completed | Applied Science & Performance Institute | 60 | 2025-01-10 | 2025-09-16 |
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