8 completed, 1 withdrawn. 9 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 8, Withdrawn 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 1 | Completed 1 |
Follow Cleft Palate: new trials by email Literature Review of Cleft Palate trials Research Report on Cleft Palate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Suprazygomatic Block in Cleft Palate Surgery in Children Bupivacaine, Dexmedetomidine, paracetamol - Cleft Palate | Phase 2 | Completed | Assiut University | 80 | 2018-01-14 | 2018-09-24 |
| Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate Surgery Levobupivacaine, Bupivacaine - Recovery After Cleft Palate Surgery | Phase 2 / Phase 3 | Completed | Assiut University | 60 | 2016-01-01 | 2017-09-07 |
| IV Acetaminophen in Children Undergoing Palatoplasty IV acetaminophen, Placebo - Cleft Palate | Phase 2 | Withdrawn | Nationwide Children's Hospital | 2015-12-01 | 2016-03-08 | |
| Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair Botulinum Toxin Type A, Normal Saline Injection - Cleft Lip, Scarring | Phase 1 / Phase 2 | Completed | The University of Texas Health Science Center, Houston | 30 | 2015-12-01 | 2021-11-03 |
| Description of Pain in Pediatric Patients With Cleft Lip and Palate Undergoing Alveolar Grafting Using Two Surgical Strategies: Stem Cells and Autogenous Iliac Crest Bone (Pain Evaluation in Children Undergoing Alveolar Grafting: Stem Cells vs. Iliac Crest Bone) Autogenous Iliac Crest Bone Grafting, Bioengineered Alveolar Grafting (SHED + Scaffold) - Clift Lip, Cleft Palate | Phase 1 / Phase 2 | Completed | Hospital Sirio-Libanes | 20 | 2015-03-01 | 2026-07-29 |
| Cell Therapy for Craniofacial Bone Defects Ixmyelocel-T, Autogenous Bone Grafting - Cleft Palate, Trauma | Phase 1 / Phase 2 | Completed | University of Michigan | 18 | 2012-08-01 | 2017-05-04 |
| Does Use of Rigid Fixation After Removing Distraction Osteogenesis Device Reduce the Relapse? mini plate - Cleft Palate, Maxillary Hypoplasia | Phase 2 | Completed | Shiraz University of Medical Sciences | 20 | 2011-02-01 | 2015-01-30 |
| Preventing Complications in Cleft Palate Repair With Antibiotics Unasyn, saline solution - Cleft Palates | Phase 2 | Completed | Joseph Losee | 224 | 2008-05-01 | 2018-02-01 |
| Cleft Palate Surgery and Speech Development Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair - Cleft Lip, Cleft Palate | Phase 2 | Completed | University of Florida | 475 | 1996-02-01 | 2011-09-20 |
Cleft Lip (3) · Alveolar Bone Loss (1) · Cicatrix (1) · Pain, Postoperative (1) · Retrognathia (1) · Speech (1) · Wounds and Injuries (1)
Congenital Abnormalities (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (9) · Craniofacial Abnormalities (9) · Jaw Abnormalities (9) · Jaw Diseases (9) · Maxillofacial Abnormalities (9) · Mouth Abnormalities (9) · Mouth Diseases (9) · Musculoskeletal Abnormalities (9) · Musculoskeletal Diseases (9) · Stomatognathic Diseases (9) · Stomatognathic System Abnormalities (9) · Lip Diseases (3) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2)
Acetaminophen (2) · Bupivacaine (2) · Saline Solution (2) · Ampicillin (1) · Botulinum Toxins, Type A (1) · Dexmedetomidine (1) · Levobupivacaine (1) · Sulbactam (1) · sultamicillin (1)
Assiut University (2) · Hospital Sirio-Libanes (1) · Joseph Losee (1) · Nationwide Children's Hospital (1) · Shiraz University of Medical Sciences (1) · The University of Texas Health Science Center, Houston (1) · University of Florida (1) · University of Michigan (1)
United States (5) · Brazil (2) · Egypt (2) · Iran (1)
Darnell Kaigler, DDS, PhD (1) · Jaecel O Shah, MD (1) · Joseph Losee, MD (1) · Negin Matini, DMD (1) · Reza Tabrizi, DMD (1) · Touba Karagah, DMD (1) · William N Williams, Ph.D (1)
R01DE010437 (1)