31 unknown, 28 completed, 19 recruiting, 5 terminated. 30 Not applicable, 8 Phase 2, 6 Phase 3, 2 Phase 4.
Follow Chronic Thromboembolic Pulmonary Hypertension: new trials by email Literature Review of Chronic Thromboembolic Pulmonary Hypertension trials Research Report on Chronic Thromboembolic Pulmonary Hypertension
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Continuous Remote Haemodynamic Monitoring With CardioMEMS™ Following Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension: CardioMEMS - Chronic Thromboembolic Pulmonary Hypertension, Residual Pulmonary Hypertension | Not yet recruiting | Hospital Universitario 12 de Octubre | 30 | 2026-10-01 | 2026-08-11 | |
| Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance Routine clinical care (no study intervention) - Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension | Recruiting | Azienda Ospedaliero-Universitaria Careggi | 5000 | 2026-06-19 | 2026-10-15 | |
| Nailfold Capillaroscopy in PH Standard of Care therapy - Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH), Pulmonary Hypertension (World Health Organization Group 3) | Recruiting | University of Glasgow | 60 | 2026-05-20 | 2026-08-17 | |
| Cardiac Self-Efficacy in Patients With Chronic Thromboembolic Pulmonary Hypertension Chronic Thromboembolic Pulmonary Hypertension | Recruiting | Damascus University | 10 | 2025-11-20 | 2025-12-17 | |
| Registry of Patients With chrOnic thromboemboLic Pulmonary hypErTension Pulmonary endarterectomy, Balloon pulmonary angioplasty, Pulmonary hypertension-specific therapy - Chronic Thromboembolic Pulmonary Hypertension | Recruiting | Irina E. Chazova | 500 | 2025-05-01 | 2025-12-12 | |
| Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART) Riociguat, Routine Treatment - Chronic Thromboembolic Pulmonary Hypertension | Phase 3 | Recruiting | Suqiao Yang | 68 | 2025-03-21 | 2025-04-30 |
| Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Embolism Chronic Thromboembolic Pulmonary Hypertension | Recruiting | Ester Ashraf Faried Beshay | 100 | 2025-01-01 | 2025-12-01 | |
| Switching of Sildenafil to Riociguat in CTEPH Patients Riociguat (Adempas) - Chronic Thromboembolic Pulmonary Hypertension | Phase 4 | Recruiting | Chinese University of Hong Kong | 30 | 2024-07-25 | 2025-05-29 |
| Prehabilitation for Patients Undergoing Elective Cardiac Surgery Physical exercise, Educational program and respiration physiotherapy - Coronary Artery Disease, Valvular Heart Disease | Not applicable | Completed | Hospital Universitario 12 de Octubre | 86 | 2024-06-01 | 2026-07-15 |
| Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy in Pulmonary Vascular Disease (PVD) 6-minute walk distance (6MWD) test on ambient air, 6-minute walk distance test with supplemental oxygen - Pulmonary Vascular Disorder, Chronic Thromboembolic Pulmonary Hypertension | Not applicable | Completed | University of Zurich | 40 | 2024-04-01 | 2025-12-10 |
| BPA vs. PEA in CTEPH Pulmonary endarterectomy, Balloon pulmonary angioplasty - Chronic Thromboembolic Pulmonary Hypertension | Not applicable | Recruiting | University of Aarhus | 139 | 2024-04-01 | 2024-04-29 |
| Balloon Pulmonary Angioplasty vs. Combined Approach With Pulmonary Artery Denervation in CTEPH: Effectiveness Comparison Balloon Pulmonary Angioplasty combined with Pulmonary Artery Denervation, Balloon Pulmonary Angioplasty with Sham Pulmonary Artery Denervation - Chronic Thromboembolic Pulmonary Hypertension | Phase 2 / Phase 3 | Unknown | Boris Dzudovic | 20 | 2024-04-01 | 2024-04-02 |
| Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients Chronic Thromboembolic Pulmonary Hypertension, Physical Disability | Recruiting | University of Sao Paulo General Hospital | 50 | 2024-02-29 | 2026-06-22 | |
| 129Xe MRI Cardiopulmonary Hyperpolarized Xe129, Oxygen Administration - Interstitial Lung Disease, Chronic Thromboembolic Pulmonary Hypertension | Phase 2 | Recruiting | Bastiaan Driehuys | 125 | 2024-01-12 | 2026-02-04 |
| Impact of Pulmonary Endarterectomy on Sleep-Related Breathing Disorders in CTEPH: The IPES Trial Pulmonary endarterectomy - Sleep-Disordered Breathing, Chronic Thromboembolic Pulmonary Hypertension | Unknown | Marmara University | 100 | 2023-12-20 | 2023-10-04 | |
| High Altitude (HA) Residents With Pulmonary Vascular Diseases (PVD), 6 Minute Walk Distance (6MWD) Assessed at 2840m (HA) With and Without Supplemental Oxygen Therapy (SOT) 6-minute walk distance (6MWD) test, 6-minute walk distance (6MWD) test with supplemental oxygen (3 l/min, nasal) - Pulmonary Vascular Disease, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-09-23 | 2023-10-05 |
| High Altitude (HA) Residents With Pulmonary Vascular Diseseases (PVD), Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) vs Sea Level (LA) Relocation from HA to LA - Pulmonary Vascular Disease, Pulmonary Arterial Hypertension | Not applicable | Unknown | University of Zurich | 36 | 2023-09-23 | 2023-10-23 |
| HA Residents With PVD, SDB Assessed at HA (2840m) vs LA (Sea Level) Assessment without intervention at High altitude, Relocation to sea level for 2 days - Pulmonary Vascular Disease, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-09-22 | 2023-10-10 |
| Chronic Thromboembolic Disease Registry Survey - Chronic Thromboembolic Pulmonary Hypertension, Chronic Thromboembolic Disease | Recruiting | University of California, San Francisco | 100 | 2023-08-01 | 2026-07-14 | |
| HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level) Relocation to sea level - Pulmonary Vascular Disease, Pulmonary Artery Hypertension | Not applicable | Unknown | University of Zurich | 24 | 2023-07-05 | 2023-10-03 |
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Hypertension, Pulmonary (24) · Pulmonary Arterial Hypertension (19) · Pulmonary Embolism (10) · Familial Primary Pulmonary Hypertension (9) · Hypoxia (6) · Altitude Sickness (4) · Sleep Apnea Syndromes (4) · Postthrombotic Syndrome (3) · Disease (2) · Dyspnea (2) · Heart Failure (2) · Motor Activity (2) · Venous Thrombosis (2) · Acute Lung Injury (1) · Anemia (1)
Respiratory Tract Diseases (43) · Lung Diseases (40) · Cardiovascular Diseases (35) · Vascular Diseases (33) · Hypertension (24) · Embolism and Thrombosis (14) · Pathological Conditions, Signs and Symptoms (13) · Embolism (10) · Hypertension, Pulmonary (9) · Respiration Disorders (9) · Signs and Symptoms (8) · Signs and Symptoms, Respiratory (8) · Nervous System Diseases (5) · Pathologic Processes (5) · Apnea (4)
riociguat (6) · macitentan (4) · Blood Specimen Collection (2) · Exercise (2) · Oxygen (2) · Acetylcysteine (1) · Bosentan (1) · Capnography (1) · Catheter Ablation (1) · Continuous Positive Airway Pressure (1) · Observation (1) · Respiratory Therapy (1) · Restraint, Physical (1) · Surveys and Questionnaires (1) · Telerehabilitation (1)
University of Zurich (7) · Actelion (6) · International CTEPH Association (4) · University of California, San Diego (3) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Assistance Publique - Hôpitaux de Paris (2) · China-Japan Friendship Hospital (2) · Chinese Pulmonary Vascular Disease Research Group (2) · Heidelberg University (2) · Hospital Universitario 12 de Octubre (2) · Medical University of Vienna (2) · Novosibirsk Scientific Research Institute for Circulatory Pathology (2) · Papworth Hospital NHS Foundation Trust (2) · University of Giessen (2) · AHMET ZENGIN (1)
United States (19) · China (13) · Germany (13) · Poland (13) · Switzerland (12) · United Kingdom (12) · France (11) · Belgium (9) · Russia (9) · Turkey (Türkiye) (9) · Austria (7) · Denmark (7) · Canada (6) · Czechia (6) · Italy (6)
Silvia Ulrich, Prof. Dr. (5) · Rodrigo Hoyos, Dr. (4) · David Kiely, MD (2) · Alexander Chernyavskiy, PhD (1) · Alexander Romanov, PhD (1) · Alistair C Church, PhD, BSc, MB ChB, FRCP (1) · Andrew J Roscoe, FRCA (1) · Andy J Swift, PhD (1) · Andy Swift, MD (1) · Apostolos Armaganidis, MD, PhD (1) · Ardeschir Ghofrani, Prof. (1) · Argyrios Tsantes, MD, PhD (1) · Bramajee Nallamothu, MD (1) · Bruno Degano, MD, PhD (1)
PMID 30545968, PMID 39520648, PMID 41921908, PMID 12029189, PMID 15073478, PMID 16456139, PMID 17242010, PMID 17360728, PMID 1863023, PMID 18829679, PMID 19095129, PMID 19837821, PMID 20504865, PMID 20562126, PMID 20585011, PMID 20585012, PMID 21450333, PMID 21680644, PMID 21885399, PMID 21969018, PMID 22221974, PMID 22281797, PMID 23066376, PMID 23164592, PMID 25447572, PMID 25742869, PMID 25746363, PMID 26159944, PMID 26241077, PMID 26320113, PMID 27903661, PMID 28159512, PMID 28575277, PMID 28775050, PMID 28919201, PMID 29070502, PMID 29428946, PMID 29450722, PMID 29776563, PMID 30002102, PMID 30209196, PMID 30545970, PMID 30545971, PMID 32954622, PMID 33854746, PMID 33879094, PMID 34104418, PMID 34127618, PMID 34409094, PMID 35819325
2017 (1), 2018 (1), 2019 (1)