12 completed, 10 not yet recruiting, 10 recruiting, 3 active not recruiting. 30 Not applicable, 1 Early Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 30 | Completed 10, Not yet recruiting 10, Recruiting 6, Active not recruiting 2, Enrolling by invitation 2 |
| Early Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow Chronic Low-back Pain (cLBP): new trials by email Literature Review of Chronic Low-back Pain (cLBP) trials Research Report on Chronic Low-back Pain (cLBP)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Exercise-Based Strategies for Chronic Back Pain Gym settings, Physio settings, Home - based settings: exercises based on developmental positions - Chronic Low-back Pain (cLBP) | Not applicable | Not yet recruiting | Charles University, Czech Republic | 120 | 2027-07-01 | 2026-03-16 |
| Pain Science Education and Graded Exposure for Chronic Low Back Pain Pain Science Education Plus Graded Exposure, Usual Physical Therapy - Chronic Low-back Pain (cLBP) | Not applicable | Not yet recruiting | University of Chile | 82 | 2026-11-02 | 2026-09-23 |
| Hybrid mHealth for Low Back Pain Face-to-face physiotherapy and psychological care (for hybrid arm), WhatsApp-based AI chatbot for self-management (for hybrid and WhatsApp-only arms), Face-to-face physiotherapy and psychological care (No Digital Support) (for control arm) - Chronic Low-back Pain (cLBP), Non-specific Low Back Pain (NSLBP) | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 60 | 2026-11-02 | 2026-10-29 |
| TECAR Therapy in Chronic Back Pain TECAR Therapy plus Hi-EMS, Tecar therapy alone - Chronic Low-back Pain (cLBP), Non Specific Chronic Low Back Pain | Not applicable | Not yet recruiting | University of Hartford | 37 | 2026-10-19 | 2026-09-15 |
| Impact of the Receptive Music Intervention Tool (MUSIC CARE©) on Changes in the Functional Abilities of Patients With Chronic Low Back Pain Receptive Music Therapy - Low Back Pain, Kinesiophobia (Fear of Movement) | Not applicable | Not yet recruiting | LNA SANTE | 34 | 2026-10-01 | 2026-07-28 |
| Virtual Tai Chi for Chronic Low Back Pain (Spine 2027) Virtually Delivered Integrated Tai Chi, Qigong, and Meditation (VDTQM) - Low Back Pain, Chronic Low-back Pain (cLBP) | Not applicable | Not yet recruiting | New York Medical College | 600 | 2026-10-01 | 2026-08-19 |
| Comparing Non-Medicine Strategies for Improving Low Back Pain ENCompaSS (Education, Navigated Care, and Supported Self-Management) with VA Stepped Usual Care - Chronic Low-back Pain (cLBP), High-Impact Chronic Pain (HICP) | Not applicable | Not yet recruiting | Duke University | 530 | 2026-10-01 | 2026-07-28 |
| Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling Chronic Low-back Pain (cLBP) | Recruiting | Aristotle University Of Thessaloniki | 60 | 2026-09-07 | 2026-09-29 | |
| Combined and Aquatic Exercise in Chronic Low Back Pain Aquatic-exercise Program, Land-based Exercise Program, Home-based Exercise Program - Chronic Low-back Pain (cLBP) | Not applicable | Not yet recruiting | University of Beira Interior | 90 | 2026-09-01 | 2026-07-30 |
| Effects Of Vacuum Controlled Static Versus Vacuum Controlled Dynamic Dry Cupping On Pain, Range Of Motion And Disability Among Patients With Chronic Low Back Pain Vacuum-Controlled Static Dry Cupping, Vacuum-Controlled Dynamic Dry Cupping - Chronic Low-back Pain (cLBP) | Not applicable | Not yet recruiting | Lahore University of Biological and Applied Sciences | 48 | 2026-07-01 | 2026-07-22 |
| Imaging Metabolic and Perfusion Changes in Acupuncture Therapy for Myofascial Pain Syndrome Acupuncture, Sham Acupuncture, Total-Body PET/CT Imaging - Myofascial Pain Syndrome (MPS), Chronic Low-back Pain (cLBP) | Not applicable | Recruiting | University of California, Davis | 64 | 2026-05-18 | 2026-06-17 |
| Virtual Reality Based High-intensity Interval Training in Chronic Low Back Pain Virtual reality based high intensity interval training (VR-HIIT) group, High intensity interval training (HIIT) group - Chronic Low-back Pain (cLBP) | Not applicable | Completed | Universidad de Granada | 52 | 2026-02-09 | 2026-06-02 |
| Effects of Vertebral Axial Loading Walking Combined With Core Stabilization Exercises in Individuals With Chronic Low Back Pain Exercise - Core Stabilization Exercise Program, Core Stabilization Exercises Plus Vertebral Axial Loading Walking Training - Chronic Low-back Pain (cLBP) | Not applicable | Active not recruiting | Hacettepe University | 20 | 2026-01-19 | 2026-02-02 |
| Biopsychosocial Model-based Care Versus Routine Physical Therapy in Chronic Back Pain Biopsychosocial model based care, Routine Physical Therapy - Chronic Low-back Pain (cLBP) | Not applicable | Completed | Lahore University of Biological and Applied Sciences | 80 | 2025-11-04 | 2026-06-12 |
| Clinical Research of Effectiveness and Safety of Herbal Medicine Strategy for Chronic Low Back Pain Herbal Medicine Strategy, Standard Korean Medicine Treatment - Chronic Low-back Pain (cLBP) | Not applicable | Enrolling by invitation | Jaseng Medical Foundation | 150 | 2025-10-31 | 2025-11-19 |
| Treatment Validation for Myofascial Pain Dry Needling, Sham Dry Needling, NUN Biomarker - Chronic Low-back Pain (cLBP), Myofacial Pain | Not applicable | Recruiting | Ajay Wasan, MD, Msc | 80 | 2025-10-06 | 2026-10-01 |
| Effects of PEMM in Chronic Low Back Pain Women With Urinary Incontinence PEMM with Theragun, Active Comparator: Control - Chronic Low-back Pain (cLBP), Urinary Incontinence (UI) | Not applicable | Recruiting | Hamad Medical Corporation | 200 | 2025-09-29 | 2026-01-20 |
| Acceptance and Commitment Therapy Plus Exercise for Older People With Chronic Low-back Pain: A Pragmatic Cluster Randomised Controlled Trial Acceptance and commitment therapy (ACT), back exercise, back care education - Chronic Low-back Pain (cLBP) | Not applicable | Recruiting | The Hong Kong Polytechnic University | 100 | 2025-09-01 | 2025-10-08 |
| Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain Active rTMS, Sham rTMS, Psychologically-informed physiotherapy (PiP) - Chronic Low-back Pain (cLBP) | Not applicable | Recruiting | Laval University | 96 | 2025-06-11 | 2026-01-20 |
| Melatonin for Patients With Chronic Low Back Pain Melatonin 10 mg, Placebo - Chronic Low-back Pain (cLBP) | Phase 3 | Active not recruiting | Bart Koes | 222 | 2025-04-11 | 2026-09-09 |
Showing 20 of 37. Sign in to see all of them.
Low Back Pain (6) · Back Pain (4) · Chronic Pain (4) · Motor Activity (3) · Agnosia (2) · Kinesiophobia (2) · Pain (2) · Facial Pain (1) · Femoral Neuropathy (1) · Hyperthermia (1) · Intervertebral Disc Degeneration (1) · Marijuana Abuse (1) · Myofascial Pain Syndromes (1) · Neuralgia (1) · Nociplastic Pain (1)
Neurologic Manifestations (17) · Pathological Conditions, Signs and Symptoms (17) · Signs and Symptoms (17) · Pain (14) · Back Pain (5) · Nervous System Diseases (5) · Mental Disorders (4) · Behavior (3) · Anxiety Disorders (2) · Mononeuropathies (2) · Musculoskeletal Diseases (2) · Neurobehavioral Manifestations (2) · Neuromuscular Diseases (2) · Perceptual Disorders (2) · Peripheral Nervous System Diseases (2)
Transcutaneous Electric Nerve Stimulation (2) · Acceptance and Commitment Therapy (1) · Acupuncture Therapy (1) · Counseling (1) · Dry Needling (1) · Educational Status (1) · Electric Stimulation Therapy (1) · Exercise (1) · Exercise Therapy (1) · High-Intensity Interval Training (1) · Meditation (1) · Melatonin (1) · Physical Therapy Modalities (1) · Population Groups (1) · Qigong (1)
Kutahya Health Sciences University (2) · Lahore University of Biological and Applied Sciences (2) · The Hong Kong Polytechnic University (2) · Ajay Wasan, MD, Msc (1) · Aristotle University Of Thessaloniki (1) · Bart Koes (1) · Cairo University (1) · Cardenal Herrera University (1) · Charles University, Czech Republic (1) · Dokuz Eylul University (1) · Duke University (1) · Firat University (1) · Hacettepe University (1) · Hamad Medical Corporation (1) · Instituto Politécnico de Leiria (1)
Turkey (Türkiye) (7) · Pakistan (5) · United States (5) · Spain (4) · Hong Kong (2) · Portugal (2) · Canada (1) · China (1) · Czechia (1) · Egypt (1) · France (1) · Germany (1) · Greece (1) · Netherlands (1) · Qatar (1)
Diogo Monteiro, PhD (2) · Abhijit J Chaudhari, PhD (1) · Ajay Wasan, MD, MSc (1) · Dr. Faiza Sharif, PhD (1) · Eman R Aboturky, MSc (1) · Emrah Afsar, Phd (1) · Henrique Neiva, PhD (1) · In-Hyuk Ha, PhD (1) · Joana Borges, PT (1) · Kang Kim, PhD (1) · Marc Terradas-Monllor, PhD (1) · Maryam Arshad, DPT (1)
PMID 10767807, PMID 11494188, PMID 15234479, PMID 15834344, PMID 17304528, PMID 17304690, PMID 21720817, PMID 21938471, PMID 21943614, PMID 25691362, PMID 26019961, PMID 26487293, PMID 28339852, PMID 29067433, PMID 29143807, PMID 31160632, PMID 31899561, PMID 33620534, PMID 34337021, PMID 34552791, PMID 34884271, PMID 35264471, PMID 35389057, PMID 40392887, PMID 40510459, PMID 41587077, PMID 42846470, PMID 7777823, PMID 8844907, PMID 8961451
R33AT012187 (1), R33AT012282 (1)