682 completed, 127 unknown, 95 recruiting, 76 terminated. 335 Not applicable, 161 Phase 2, 145 Phase 3, 129 Phase 4, 98 Phase 1.
Follow Chronic Kidney Disease: new trials by email Literature Review of Chronic Kidney Disease trials Research Report on Chronic Kidney Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Veteran Centered Meal Intervention in Chronic Kidney Disease Medically tailored meals (MTMs) - Chronic Kidney Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 100 | 2027-10-01 | 2026-09-03 |
| Breakthrough - T1DM and Chronic Kidney Disease Tegoprubart, Islet Cell Transplant - Diabete Type 1, Chronic Kidney Disease | Phase 1 / Phase 2 | Recruiting | University of Chicago | 10 | 2027-04-29 | 2026-08-20 |
| Patient-centred Intervention With Virtual Support for Obesity and Kidney Transplant Access Semaglutide, Virtual Weight Management Coaching - Obesity, Chronic Kidney Disease | Phase 4 | Not yet recruiting | Kristin Clemens | 880 | 2027-01-01 | 2026-10-05 |
| Clinical Performance of the Therapy Option FlexPoint of the PD Cycler Sleep•Safe Harmony PD cycler - Renal Failure, Chronic Kidney Disease | Not applicable | Not yet recruiting | Fresenius Medical Care Deutschland GmbH | 24 | 2026-12-01 | 2026-09-03 |
| Heart-Kidney-Diabetes Multidisciplinary Care MOdels for CardiovascuLar Health In Patients With Chronic Kidney DiSease and Diabetes: A PragmaTIC Cluster Randomized Controlled Trial (HOLISTIC) The intervention with the MCM is Kidney-Heart GDMT initiation and titration for dose optimization (as clinically tolerated), within 4 months of enrollment in the study. - Chronic Kidney Disease, Type II Diabetes | Phase 4 | Not yet recruiting | Baim Institute for Clinical Research | 570 | 2026-12-01 | 2026-09-10 |
| Optimised Cardiovascular and Renal Protection in Patients With Chronic Kidney Disease and Cardiovascular Disease Multidisciplinary Cardio-Renal Care - Chronic Kidney Disease, Heart Failure With Preserved Ejection Fraction (HFPEF) | Not applicable | Recruiting | Odense University Hospital | 500 | 2026-10-01 | 2026-10-15 |
| Targeted Nutritional Management for Children With Chronic Kidney Disease Chronic Kidney Disease | Not yet recruiting | Assiut University | 128 | 2026-10-01 | 2026-08-31 | |
| Nicotinamide Riboside Supplementation in Chronic Kidney Disease Nicotinamide Riboside (NR), Matched Placebo (Capsules) - Chronic Kidney Disease | Phase 2 | Not yet recruiting | University of California, San Diego | 30 | 2026-10-01 | 2026-07-15 |
| Capillary Sampling in Clinical Populations Undergoing Monitoring Blood sampling with capillary sampling device(s) - Chronic Kidney Disease, Autoimmune Diseases | Not yet recruiting | University of Edinburgh | 1000 | 2026-10-01 | 2026-09-03 | |
| CXCR2 Leucocyte Expression Level as a Predictive Factor of Coronary Artery Calcification Progression in Advanced Chronic Kidney Disease Patients Thoracic CT, Blood samples - Chronic Kidney Disease, Coronary Arteries Calcifications | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire, Amiens | 100 | 2026-10-01 | 2026-09-10 |
| Food As Medicine to Reduce CKD Burden in Health Disparity Populations Culinary Medicine Nutrition and Cooking Education - Chronic Kidney Disease | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 500 | 2026-10-01 | 2026-08-12 |
| Manual Acupuncture for Intradialytic Nausea and Vomiting in Patients Undergoing Hemodialysis: A Randomized Controlled Trial Acupuncture, sham acupuncture - Intradialytic Nausea and Vomiting, Chronic Kidney Disease | Not applicable | Not yet recruiting | Universitas Indonesia | 20 | 2026-10-01 | 2026-10-22 |
| Manual Acupuncture for Intradialytic Fatigue in CKD Patients Manual Acupuncture, Sham Acupuncture - Intradialytic Fatigue, Chronic Kidney Disease | Not applicable | Not yet recruiting | Universitas Indonesia | 19 | 2026-10-01 | 2026-10-21 |
| Holistic CRM Care vs Standard of Care in a Primary Care Setting CRM care - Cardio Vascular Disease, Diabetes (DM) | Not yet recruiting | Danderyd Hospital | 6000 | 2026-09-16 | 2026-09-14 | |
| Investigating Vascular Properties of HEMI and SPG Signals in Individuals With or at Risk for Chronic Kidney Disease HEMI device, SPG-NINOX device - Chronic Kidney Disease, Hypertension (HTN) | Not applicable | Not yet recruiting | Institut National de la Santé Et de la Recherche Médicale, France | 165 | 2026-09-15 | 2026-07-31 |
| A Research Study Looking Into How a Single Dose of the Medicine NNC0537-1482 Moves Through the Body of Participants With Normal or Reduced Kidney Function NNC0537-1482, Placebo (for dilution only) - Chronic Kidney Disease | Phase 1 | Not yet recruiting | Novo Nordisk A/S | 54 | 2026-09-04 | 2026-09-09 |
| Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring. Sotagliflozin initiation - Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM) | Phase 2 | Not yet recruiting | HealthPartners Institute | 80 | 2026-09-01 | 2026-08-27 |
| NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in Middle-Aged Adults (PREMAP) Digital health interventions - Type 2 Diabetes, Coronary Heart Disease | Not applicable | Recruiting | University of Eastern Finland | 1400 | 2026-09-01 | 2026-10-06 |
| Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD) Early goal-directed Cardio-Kidney-Metabolic (CKM) care, Standard care (Comparison arm) - Diabetic Kidney Disease (DKD), Type 2 Diabetes Mellitus (T2DM) | Not applicable | Recruiting | Sunnybrook Health Sciences Centre | 100 | 2026-08-26 | 2026-09-04 |
| Sarcopenia in Chronic Kidney Disease (CKD) Patients Valine, EEA - Chronic Kidney Disease, Sarcopenia | Early Phase 1 | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 20 | 2026-08-24 | 2026-08-11 |
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finerenone (24) · Sevelamer (23) · paricalcitol (23) · Darbepoetin alfa (20) · Exercise (17) · Sodium Bicarbonate (15) · Cholecalciferol (14) · Cinacalcet (14) · Epoetin Alfa (14) · hematide (14) · peginesatide (14) · dapagliflozin (13) · Calcitriol (10) · Standard of Care (10) · cholebine (10)
Bayer (34) · Amgen (29) · AstraZeneca (29) · Novo Nordisk A/S (19) · VA Office of Research and Development (15) · Tanabe Pharma Corporation (13) · Affymax (12) · Universitaire Ziekenhuizen KU Leuven (12) · Astellas Pharma Inc (10) · Duke University (10) · Genzyme, a Sanofi Company (10) · University of Colorado, Denver (9) · AbbVie (prior sponsor, Abbott) (8) · Eli Lilly and Company (8) · Indiana University (8)
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Vice President, Clinical Development (8) · Geoffrey A Block, MD (7) · Joel Melnick, MD (7) · Pieter Evenepoel, MD, PhD (5) · Alp Ikizler, MD (4) · Crystal A Gadegbeku, MD (4)
PMID 40576086, PMID 35224730, PMID 36791280, PMID 37870148, PMID 23797006, PMID 33782940, PMID 34164803, PMID 36472416, PMID 23343061, PMID 23343062, PMID 33107592, PMID 36005278, PMID 37916745, PMID 38018702, PMID 38189593, PMID 41196655, PMID 18328118, PMID 28756065, PMID 35018639, PMID 39963952, PMID 24492525, PMID 24508475, PMID 24890823, PMID 25349205, PMID 27716149, PMID 28506446, PMID 28741050, PMID 31664940, PMID 31939531, PMID 32390133, PMID 32588430, PMID 32734207, PMID 32778748, PMID 32829751, PMID 33115916, PMID 33118160, PMID 35314481, PMID 36567000, PMID 37872654, PMID 37889573, PMID 38564654, PMID 38622766, PMID 38770818, PMID 38825327, PMID 40526444, PMID 40658498, PMID 10215341, PMID 10432410, PMID 10711412, PMID 10759586
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