33 completed. 33 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 33 | Completed 33 |
| Phase 2 | 1 | Completed 1 |
Follow Choroid Plexus Neoplasms: new trials by email Literature Review of Choroid Plexus Neoplasms trials Research Report on Choroid Plexus Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors azurin-derived cell-penetrating peptide p28 - Teratoid Tumor, Atypical, Choroid Plexus Neoplasms | Phase 1 | Completed | Pediatric Brain Tumor Consortium | 18 | 2013-08-01 | 2017-08-07 |
| RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma 3-Dimensional Conformal Radiation Therapy, Gamma-Secretase Inhibitor RO4929097, Intensity-Modulated Radiation Therapy - Acoustic Schwannoma, Adult Anaplastic (Malignant) Meningioma | Phase 1 | Completed | National Cancer Institute (NCI) | 22 | 2010-05-01 | 2015-09-29 |
| Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors vorinostat, temozolomide, diagnostic laboratory biomarker analysis - Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Completed | National Cancer Institute (NCI) | 27 | 2010-02-01 | 2013-05-03 |
| Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma vorinostat, bortezomib, pharmacological study - Childhood Burkitt Lymphoma, Childhood Central Nervous System Choriocarcinoma | Phase 1 | Completed | National Cancer Institute (NCI) | 20 | 2009-08-01 | 2013-07-02 |
| ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors veliparib, temozolomide, pharmacological study - Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Germ Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 31 | 2009-07-01 | 2014-07-09 |
| A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors temsirolimus, pharmacological study, cytokine levels - Brain and Central Nervous System Tumors, Metastatic Cancer | Phase 1 | Completed | City of Hope Medical Center | 12 | 2008-06-01 | 2018-04-17 |
| Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors enzastaurin hydrochloride - Brain and Central Nervous System Tumors, Neuroblastoma | Phase 1 | Completed | Pediatric Brain Tumor Consortium | 32 | 2007-06-01 | 2012-03-06 |
| Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma ispinesib, laboratory biomarker analysis, pharmacological study - Childhood Burkitt Lymphoma, Childhood Central Nervous System Germ Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 30 | 2006-06-01 | 2013-01-16 |
| Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors carboplatin, talabostat mesylate, temozolomide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 26 | 2005-12-01 | 2012-03-15 |
| Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors irinotecan hydrochloride, temozolomide, vincristine sulfate - Brain and Central Nervous System Tumors, Unspecified Childhood Solid Tumor, Protocol Specific | Phase 1 | Completed | Children's Oncology Group | 42 | 2005-10-01 | 2023-10-02 |
| VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors laromustine - Brain and Central Nervous System Tumors | Phase 1 | Completed | Pediatric Brain Tumor Consortium | 42 | 2005-02-01 | 2011-06-30 |
| Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment bortezomib, temozolomide, pharmacological study - Brain and Central Nervous System Tumors, Lymphoma | Phase 1 | Completed | City of Hope Medical Center | 25 | 2005-01-01 | 2013-02-15 |
| Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors lenalidomide, perfusion-weighted magnetic resonance imaging, diffusion-weighted magnetic resonance imaging - Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Germ Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 45 | 2004-11-01 | 2013-09-30 |
| Cilengitide in Treating Children With Refractory Primary Brain Tumors cilengitide, laboratory biomarker analysis - Childhood Central Nervous System Germ Cell Tumor, Childhood Choroid Plexus Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 24 | 2003-07-01 | 2013-09-30 |
| Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors O6-benzylguanine, temozolomide, filgrastim - Childhood Central Nervous System Germ Cell Tumor, Childhood Choroid Plexus Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 72 | 2002-10-01 | 2013-09-30 |
| FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia romidepsin - Blastic Phase Chronic Myelogenous Leukemia, Childhood Central Nervous System Germ Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 30 | 2002-09-01 | 2013-01-16 |
| Thalidomide and Docetaxel in Treating Patients With Advanced Cancer docetaxel, thalidomide - Cancer | Phase 1 | Completed | Case Comprehensive Cancer Center | 26 | 2002-07-01 | 2010-06-11 |
| Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer filgrastim, carboplatin, etoposide - Brain and Central Nervous System Tumors, Lymphoma | Phase 1 | Completed | Roswell Park Cancer Institute | 1 | 2002-03-01 | 2011-03-01 |
| ABT-751 in Treating Young Patients With Refractory Solid Tumors ABT-751 - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 90 | 2002-03-01 | 2012-03-15 |
| SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors lonafarnib - Brain and Central Nervous System Tumors | Phase 1 | Completed | Pediatric Brain Tumor Consortium | 53 | 2002-01-01 | 2009-10-14 |
Showing 20 of 33. Sign in to see all of them.
Astrocytoma (33) · Medulloblastoma (32) · Oligodendroglioma (28) · Familial ependymoma (23) · Optic Nerve Glioma (23) · Central Nervous System Neoplasms (21) · Neuroblastoma (11) · Meningioma (10) · Sarcoma (10) · Brain Neoplasms (9) · Neuroectodermal Tumors, Primitive (9) · Neuroectodermal Tumors, Primitive, Peripheral (9) · Pinealoma (9) · Rhabdoid Tumor (9)
Brain Diseases (33) · Central Nervous System Diseases (33) · Cerebral Ventricle Neoplasms (33) · Neoplasms by Histologic Type (33) · Neoplasms by Site (33) · Neoplasms, Germ Cell and Embryonal (33) · Neoplasms, Glandular and Epithelial (33) · Neoplasms, Nerve Tissue (33) · Neoplasms, Neuroepithelial (33) · Nervous System Diseases (33) · Nervous System Neoplasms (33) · Neuroectodermal Tumors (33) · Neoplasms (29) · Cranial Nerve Diseases (26) · Glioma (26)
Temozolomide (9) · Filgrastim (6) · Carboplatin (5) · Peripheral Blood Stem Cell Transplantation (4) · Etoposide (3) · O(6)-benzylguanine (3) · Bortezomib (2) · Cyclophosphamide (2) · Granulocyte Colony-Stimulating Factor (2) · Vincristine (2) · Vorinostat (2) · 2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide (1) · 90Y-octreotide, DOTA-Tyr(3)- (1) · ABT751 (1) · Busulfan (1)
National Cancer Institute (NCI) (12) · National Institutes of Health Clinical Center (CC) (5) · Pediatric Brain Tumor Consortium (5) · Children's Oncology Group (2) · City of Hope Medical Center (2) · Case Comprehensive Cancer Center (1) · Daiichi Sankyo (1) · Duke University (1) · Novartis Pharmaceuticals (1) · Roswell Park Cancer Institute (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · University of Pittsburgh (1)
United States (33) · Canada (4) · Australia (2)
Elizabeth Fox, MD (2) · Jana Portnow, MD (2) · AeRang Kim, MD (1) · Allen R. Chen, MD, PhD, MHS (1) · Amar Gajjar (1) · Antonio Omuro (1) · Barbara Jean Bambach, MD (1) · Bruce H. Cohen, MD (1) · Denise Adams, MD (1) · Elizabeth Lowe (1) · Henry S. Friedman, MD (1) · Holly Meany, MD (1) · Jack Su (1) · Jodi Muscal (1) · John P. Perentesis, MD (1)
PMID 11410496, PMID 16234526, PMID 16533779, PMID 16914576, PMID 17634493, PMID 17941066, PMID 18281544, PMID 18281546, PMID 18470481, PMID 19075272, PMID 19430790, PMID 20044751, PMID 20049936, PMID 20460632, PMID 21850464, PMID 23554030, PMID 9849694
U01CA081457 (6), U01CA097452 (4), P30CA033572 (2), P30CA008748 (1), P30CA043703 (1), U01CA069856 (1)