8 completed, 2 terminated, 1 active not recruiting, 1 unknown. 13 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 13 | Completed 8, Terminated 2, Active not recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
Follow Choroid Plexus Neoplasms: new trials by email Literature Review of Choroid Plexus Neoplasms trials Research Report on Choroid Plexus Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers Nivolumab, EKG, MRI Brain and/or spine - Medulloblastoma, Ependymoma | Phase 2 | Terminated | National Cancer Institute (NCI) | 136 | 2017-07-13 | 2026-10-27 |
| Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors carboplatin, dasatinib, etoposide phosphate - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 / Phase 2 | Terminated | City of Hope Medical Center | 7 | 2008-09-10 | 2026-11-04 |
| Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma Induction Chemotherapy, Low-Risk Therapy, High-Risk Therapy - Brain and Central Nervous System Tumors | Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 293 | 2007-12-17 | 2026-10-16 |
| Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer bevacizumab, placebo, magnetic resonance imaging - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2007-06-01 | 2014-05-09 |
| Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment cyproheptadine hydrochloride, megestrol acetate - Brain Tumor, Central Nervous System Tumors | Phase 2 | Completed | University of South Florida | 70 | 2003-06-01 | 2014-02-03 |
| Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor EGb761, donepezil hydrochloride, cognitive assessment - Brain and Central Nervous System Tumors, Radiation Toxicity | Phase 2 | Completed | Wake Forest University Health Sciences | 68 | 2001-07-01 | 2021-09-09 |
| Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors temozolomide - Brain and Central Nervous System Tumors, Neuroblastoma | Phase 2 | Completed | Duke University | 2000-08-01 | 2013-06-20 | |
| Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors filgrastim, temozolomide, peripheral blood stem cell transplantation - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 / Phase 2 | Completed | Duke University | 30 | 2000-08-01 | 2013-06-20 |
| Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma becatecarin - Brain and Central Nervous System Tumors, Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 200 | 2000-07-01 | 2013-02-05 |
| Irinotecan in Treating Children With Refractory Solid Tumors irinotecan hydrochloride - Childhood Central Nervous System Germ Cell Tumor, Childhood Choroid Plexus Tumor | Phase 2 | Completed | Children's Oncology Group | 181 | 1999-10-01 | 2013-06-14 |
| Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer aldesleukin, autologous tumor cell vaccine, filgrastim - Brain and Central Nervous System Tumors | Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 1998-08-01 | 2013-04-08 | |
| Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor filgrastim, carboplatin, cisplatin - Brain and Central Nervous System Tumors, Neuroblastoma | Phase 2 | Withdrawn | NYU Langone Health | 1997-11-01 | 2015-12-03 | |
| Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors carboplatin, cisplatin, cyclophosphamide - Brain and Central Nervous System Tumors, Neuroblastoma | Phase 2 | Unknown | Children's Cancer and Leukaemia Group | 50 | 1992-06-01 | 2013-09-20 |
Astrocytoma (10) · Central Nervous System Neoplasms (10) · Oligodendroglioma (9) · Medulloblastoma (8) · Neuroblastoma (7) · Familial ependymoma (6) · Brain Neoplasms (5) · Optic Nerve Glioma (5) · Ependymoma (4) · Meningioma (4) · Sarcoma (4) · Burkitt Lymphoma (3) · Dendritic Cell Sarcoma, Interdigitating (3) · Glioma (3)
Brain Diseases (13) · Central Nervous System Diseases (13) · Cerebral Ventricle Neoplasms (13) · Neoplasms by Histologic Type (13) · Neoplasms by Site (13) · Nervous System Diseases (13) · Nervous System Neoplasms (13) · Neoplasms (12) · Neoplasms, Germ Cell and Embryonal (12) · Neoplasms, Glandular and Epithelial (12) · Neoplasms, Nerve Tissue (12) · Neoplasms, Neuroepithelial (12) · Neuroectodermal Tumors (12) · Neuroectodermal Tumors, Primitive (10) · Brain Neoplasms (8)
Carboplatin (4) · Cisplatin (4) · Cyclophosphamide (4) · Filgrastim (3) · Methotrexate (3) · Peripheral Blood Stem Cell Transplantation (3) · Radiotherapy (3) · Temozolomide (3) · Vincristine (3) · Etoposide (2) · Bevacizumab (1) · Blotting, Western (1) · Carmustine (1) · Cyproheptadine (1) · Dasatinib (1)
National Cancer Institute (NCI) (3) · Duke University (2) · Barbara Ann Karmanos Cancer Institute (1) · Children's Cancer and Leukaemia Group (1) · Children's Oncology Group (1) · City of Hope Medical Center (1) · NYU Langone Health (1) · St. Jude Children's Research Hospital (1) · University of South Florida (1) · Wake Forest University Health Sciences (1)
United States (12) · Canada (3) · Australia (2) · Puerto Rico (2) · Argentina (1) · Ireland (1) · Netherlands (1) · New Zealand (1) · Switzerland (1) · United Kingdom (1)
Henry S. Friedman, MD (2) · Amar Gajjar, MD (1) · Anne-Marie Langevin, MD (1) · Edward G. Shaw, MD (1) · Esteban Abella, MD (1) · Jennifer L. Mayer, MD (1) · Jonathan L. Finlay, MB, ChB (1) · Judith K. Sato, MD (1) · Kevin Camphausen, M.D. (1) · Lisa Bomgaars (1) · Monica Loghin (1) · Richard Grundy, MD, PhD (1)
PMID 16549835, PMID 17610262, PMID 18989154, PMID 29778738, PMID 33502920, PMID 33945291, PMID 40721826
N01CM62202 (1), P30CA016672 (1), P30CA022453 (1), P30CA033572 (1), R01CA154619 (1), U10CA081851 (1), U10CA081920 (1), U10CA098543 (1)