7 completed, 2 terminated. 9 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 7, Terminated 2 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
Follow Childhood Germ Cell Tumor: new trials by email Literature Review of Childhood Germ Cell Tumor trials Research Report on Childhood Germ Cell Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors carboplatin, dasatinib, etoposide phosphate - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 / Phase 2 | Terminated | City of Hope Medical Center | 7 | 2008-09-03 | 2023-07-14 |
| Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors carboplatin, talabostat mesylate, temozolomide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 26 | 2005-12-01 | 2012-03-15 |
| ABT-751 in Treating Young Patients With Refractory Solid Tumors ABT-751 - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 90 | 2002-03-01 | 2012-03-15 |
| Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy ixabepilone - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 30 | 2001-11-01 | 2012-03-15 |
| Busulfan in Treating Children and Adolescents With Refractory CNS Cancer busulfan - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | Pediatric Brain Tumor Consortium | 28 | 2000-11-01 | 2009-10-07 |
| Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors filgrastim, temozolomide, peripheral blood stem cell transplantation - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 / Phase 2 | Completed | Duke University | 30 | 2000-08-01 | 2013-06-20 |
| Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors O6-benzylguanine, temozolomide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 2000-06-01 | 2015-04-29 | |
| Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors amifostine trihydrate, busulfan, filgrastim - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Terminated | Masonic Cancer Center, University of Minnesota | 13 | 1998-11-01 | 2017-11-29 |
| Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors filgrastim, carboplatin, cyclophosphamide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 21 | 1997-05-31 | 2020-02-17 |
Astrocytoma (9) · Central Nervous System Neoplasms (9) · Medulloblastoma (9) · Sarcoma (9) · Choroid Plexus Neoplasms (8) · Familial ependymoma (8) · Neuroblastoma (8) · Oligodendroglioma (8) · Optic Nerve Glioma (8) · Ovarian Neoplasms (8) · Testicular Neoplasms (8) · Kidney Neoplasms (7) · Liver Neoplasms (7) · Neuroectodermal Tumors, Primitive, Peripheral (7) · Ovarian Germ Cell Cancer (7)
Brain Diseases (9) · Central Nervous System Diseases (9) · Eye Diseases (9) · Neoplasms (9) · Neoplasms by Histologic Type (9) · Neoplasms by Site (9) · Neoplasms, Connective and Soft Tissue (9) · Neoplasms, Germ Cell and Embryonal (9) · Neoplasms, Glandular and Epithelial (9) · Neoplasms, Nerve Tissue (9) · Neoplasms, Neuroepithelial (9) · Nervous System Diseases (9) · Nervous System Neoplasms (9) · Neuroectodermal Tumors, Primitive (9) · Adnexal Diseases (8)
Carboplatin (3) · Filgrastim (3) · Peripheral Blood Stem Cell Transplantation (3) · Temozolomide (3) · Busulfan (2) · ABT751 (1) · Amifostine (1) · Blotting, Western (1) · Bone Marrow Transplantation (1) · Cyclophosphamide (1) · Dasatinib (1) · Etoposide (1) · Granulocyte Colony-Stimulating Factor (1) · Ifosfamide (1) · Immunohistochemistry (1)
National Institutes of Health Clinical Center (CC) (3) · City of Hope Medical Center (1) · Duke University (1) · Masonic Cancer Center, University of Minnesota (1) · National Cancer Institute (NCI) (1) · Pediatric Brain Tumor Consortium (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1)
United States (9)
Elizabeth Fox, MD (2) · AeRang Kim, MD (1) · Allen R. Chen, MD, PhD, MHS (1) · Henry S. Friedman, MD (1) · Holly Meany, MD (1) · John P. Perentesis, MD (1) · Judith K. Sato, MD (1) · Katherine Warren, MD (1) · Sri Gururangan, MD (1)
PMID 16234526, PMID 16533779, PMID 16914576, PMID 18281544, PMID 19075272, PMID 19430790, PMID 20044751, PMID 20460632, PMID 9849694
P30CA033572 (1)