180 completed, 43 recruiting, 28 terminated, 22 unknown. 87 Phase 2, 63 Not applicable, 59 Phase 1, 31 Phase 3, 1 Phase 4.
Follow Testicular Neoplasms: new trials by email Literature Review of Testicular Neoplasms trials Research Report on Testicular Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Helping Young People With Testicular Cancer Using Virtual and Extended Reality Digital tool using extended reality - Testicular Cancer, Testis Cancer | Not applicable | Not yet recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 245 | 2027-01-04 | 2026-05-06 |
| Minimally-invasive ICG-guided Retroperitoneal Sentinel Lymph Node Dissection in the Primary Staging of Testicular Cancer Versus Standard of Care ICG-Guided Retroperitoneal Sentinel Lymph Node Biopsy, Radical Inguinal Orchiectomy - Testicular Cancer, Testicular Germ Cell Tumor | Not applicable | Not yet recruiting | Heinrich-Heine University, Duesseldorf | 171 | 2027-01-01 | 2026-07-13 |
| Personalized Cancer Support (Thrive Track) to Manage the Emotional Needs of Young Adults With Thyroid, Melanoma and Testicular Cancer, PerCS-YA Trial Internet-Based Intervention, Interview, Questionnaire Administration - Differentiated Thyroid Gland Carcinoma, Malignant Testicular Neoplasm | Not applicable | Not yet recruiting | University of Michigan Rogel Cancer Center | 142 | 2026-12-01 | 2026-10-15 |
| Patient Reported Experiences With Sparing External Oblique Fascia Vs Standard Inguinal Orchiectomy Radical inguinal orchiectomy, Radical external oblique fascia sparing orchiectomy - Testicular Cancer | Not applicable | Recruiting | Loma Linda University | 80 | 2026-12-01 | 2026-07-10 |
| Safety and Diagnostic Performance of 111In-TJD-31 SPECT Imaging in Patients With Solid Tumors 111In-TJD-31 Injection - Solid Tumors, Carcinoma | Phase 1 | Not yet recruiting | Yong He | 8 | 2026-09-01 | 2026-09-11 |
| Virtual Testis Cancer Lay Support and Survivorship Aim 2 Virtual support, Patient educational material - Testicular Cancer, Testis Cancer | Not applicable | Not yet recruiting | UNC Lineberger Comprehensive Cancer Center | 360 | 2026-09-01 | 2026-08-18 |
| Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS) Pedmark® STS - Solid Tumor Malignancies, Testicular Cancer | Phase 1 / Phase 2 | Recruiting | University of Arizona | 25 | 2026-05-18 | 2026-06-18 |
| Primary RPLND Versus Systemic Chemotherapy in Good-prognosis Metastatic Testicular Cancer primary RPLND for low-stage metasatatic seminoma, 3 courses of chemotherapy; Blemocin, Etoposide and Platinum (BEP) - Testicular Cancer, Seminoma | Not applicable | Recruiting | Sahlgrenska University Hospital | 160 | 2026-03-19 | 2026-03-27 |
| Navigation Intervention for Adolescent and Young Adult Cancer Survivors Adapted patient navigation program targeting adolescent and young adult cancer survivors - Breast Cancer, Ovarian Cancer | Not applicable | Recruiting | Kaiser Permanente | 25 | 2026-03-15 | 2026-07-06 |
| Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors Audiometric Test, Cisplatin, Computed Tomography - Hearing Loss, Metastatic Malignant Germ Cell Tumor | Phase 1 | Recruiting | City of Hope Medical Center | 44 | 2026-02-19 | 2026-04-17 |
| Evaluation of Bile Acid Concentrations and Their Signaling as Markers of Testicular Tumorigenesis and Germ Cell Tumor Chemosensitivity blood sampling, Tissue sampling - Testicular Germ Cell Cancer | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 20 | 2026-01-01 | 2026-03-11 |
| DESTINY-PANTUMOUR04 Trastuzumab deruxtecan - Adenocarcinoma (NOS), Anal Cancer | Recruiting | AstraZeneca | 100 | 2025-09-18 | 2026-09-25 | |
| Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors Tarlatamab, Concurrent Radiation Therapy, Sequential Radiation therapy - Melanoma, Medullary Thyroid Cancer | Phase 1 / Phase 2 | Recruiting | University of Arizona | 30 | 2025-09-08 | 2026-10-06 |
| A Study of GV20-0251 in Advanced or Refractory Solid Tumors GV20-0251 - HCC - Hepatocellular Carcinoma, Cholangiocarcinoma | Phase 1 | Recruiting | West China Hospital | 10 | 2025-09-04 | 2025-11-24 |
| A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy Low-dose ASA - Germ Cell Tumor, Testicular Cancer | Phase 2 | Recruiting | Wake Forest University Health Sciences | 35 | 2025-08-28 | 2026-07-24 |
| Pursuing Exploration Into the Supportive Care Needs and Intervention Preferences of Survivors of Testicular Cancer Acceptance and Commitment Therapy (ACT) Coaching, Education and Support Coaching - Testicular Cancer | Not applicable | Completed | Indiana University | 70 | 2025-08-18 | 2026-10-05 |
| Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers Computed Tomography, Fludeoxyglucose F-18, Gallium Ga 68 FAPi-46 - Anal Carcinoma, Bladder Carcinoma | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 30 | 2025-08-01 | 2026-10-20 |
| A Clinical Trial of Primary Retroperitoneal Lymph Node Dissection in Patients With Testicular Seminoma With Limited Retroperitoneal Metastases Retroperitoneal Lymph Node Dissection - Testicular Cancer | Phase 2 | Recruiting | Western University, Canada | 30 | 2025-07-17 | 2025-07-20 |
| Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors AYA Educational Information, AYA STEPS - Cancer, Breast Cancer | Not applicable | Recruiting | Duke University | 260 | 2025-07-14 | 2026-01-28 |
| A Clinical Study Investigating the Therapeutic Effects and Safety of an Investigational Cell Therapy Given With and Without an Additional Investigational Product in Males With Testicular Cancer or a Form of Cancer That Developed From Sperm CLDN6 CAR-T, CLDN6 RNA-LPX - Testicular Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 2 | Withdrawn | BioNTech SE | 2025-07-01 | 2025-07-02 |
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Carboplatin (32) · Etoposide (31) · Cisplatin (25) · Filgrastim (23) · Ifosfamide (22) · Paclitaxel (21) · Peripheral Blood Stem Cell Transplantation (16) · Bleomycin (15) · Cyclophosphamide (11) · Radiotherapy (8) · Gemcitabine (7) · Thiotepa (7) · Granulocyte Colony-Stimulating Factor (6) · Magnetic Resonance Spectroscopy (6) · Busulfan (5)
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PMID 19556464, PMID 19949018, PMID 22002018, PMID 25209242, PMID 29343557, PMID 10811682, PMID 11919245, PMID 12525530, PMID 15459300, PMID 15814645, PMID 15999102, PMID 15999362, PMID 16039331, PMID 16148284, PMID 16205699, PMID 16234526, PMID 16301596, PMID 16688776, PMID 16914576, PMID 17194908, PMID 17235042, PMID 17290059, PMID 17416851, PMID 17634488, PMID 18281544, PMID 18974373, PMID 19075272, PMID 19270260, PMID 19430790, PMID 19547919, PMID 19690306, PMID 19841031, PMID 20044751, PMID 20067918, PMID 20068553, PMID 20194867, PMID 20460632, PMID 21059637, PMID 21228314, PMID 21282539, PMID 22199322, PMID 22480131, PMID 23294513, PMID 24067488, PMID 24481001, PMID 24761742, PMID 24821309, PMID 24890451, PMID 24894084, PMID 24909177
P30CA008748 (5), P30CA068485 (4), P30CA014089 (3), P30CA033572 (3), P30CA043703 (3), U10CA027469 (3), U10CA098543 (3), U10CA180868 (3), 2019 (2), P30CA069533 (2), P30CA072720 (2), U01CA062505 (2), U01CA069856 (2), U01CA099168 (2), U10CA021115 (2)