7 completed, 2 terminated. 9 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 7, Terminated 2 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
Follow Childhood Germ Cell Tumor: new trials by email Literature Review of Childhood Germ Cell Tumor trials Research Report on Childhood Germ Cell Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors carboplatin, dasatinib, etoposide phosphate - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 / Phase 2 | Terminated | City of Hope Medical Center | 7 | 2008-09-10 | 2026-11-04 |
| Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors carboplatin, etoposide, ifosfamide - Childhood Germ Cell Tumor, Ovarian Cancer | Phase 2 | Completed | Masonic Cancer Center, University of Minnesota | 23 | 2006-12-19 | 2022-05-17 |
| Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors carboplatin, etoposide, ifosfamide - Brain Tumor, Central Nervous System Tumors | Phase 2 | Completed | Children's Oncology Group | 104 | 2004-01-01 | 2018-02-14 |
| Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors arsenic trioxide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 22 | 2001-03-01 | 2015-11-25 |
| Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors filgrastim, temozolomide, peripheral blood stem cell transplantation - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 / Phase 2 | Completed | Duke University | 30 | 2000-08-01 | 2013-06-20 |
| Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors bleomycin sulfate, amifostine trihydrate, cisplatin - Childhood Germ Cell Tumor, Drug/Agent Toxicity by Tissue/Organ | Phase 2 | Completed | Children's Oncology Group | 27 | 2000-04-01 | 2013-07-04 |
| Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell Tumors filgrastim, carboplatin, cyclophosphamide - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 2 | Terminated | UNICANCER | 45 | 1998-03-01 | 2016-06-23 |
| High-Dose Thiotepa Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Solid Tumors filgrastim, thiotepa, autologous bone marrow transplantation - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 36 | 1997-09-01 | 2013-03-07 |
| Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer filgrastim, carboplatin, thiotepa - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 1992-10-01 | 2013-06-24 |
Ovarian Neoplasms (8) · Testicular Neoplasms (8) · Teratoma (6) · Central Nervous System Neoplasms (5) · Ovarian Germ Cell Cancer (5) · Testicular Germ Cell Tumor (5) · Kidney Neoplasms (4) · Neuroblastoma (4) · Neuroectodermal Tumors, Primitive, Peripheral (4) · Sarcoma (4) · Wilms Tumor (4) · Liver Neoplasms (3) · Medulloblastoma (3) · Osteosarcoma (3) · Retinoblastoma (3)
Neoplasms (9) · Neoplasms by Site (9) · Adnexal Diseases (8) · Endocrine Gland Neoplasms (8) · Endocrine System Diseases (8) · Female Urogenital Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (8) · Genital Diseases (8) · Genital Diseases, Female (8) · Genital Diseases, Male (8) · Genital Neoplasms, Female (8) · Genital Neoplasms, Male (8) · Gonadal Disorders (8) · Male Urogenital Diseases (8) · Neoplasms by Histologic Type (8)
Carboplatin (5) · Filgrastim (5) · Thiotepa (5) · Etoposide (4) · Ifosfamide (4) · Peripheral Blood Stem Cell Transplantation (4) · Paclitaxel (2) · Radiotherapy (2) · etoposide phosphate (2) · Amifostine (1) · Arsenic Trioxide (1) · Bleomycin (1) · Blotting, Western (1) · Chemotherapy, Adjuvant (1) · Cisplatin (1)
Memorial Sloan Kettering Cancer Center (3) · Children's Oncology Group (2) · City of Hope Medical Center (1) · Duke University (1) · Masonic Cancer Center, University of Minnesota (1) · UNICANCER (1)
United States (8) · Australia (2) · Canada (2) · Switzerland (2) · France (1) · Netherlands (1) · New Zealand (1) · Puerto Rico (1)
Brian H. Kushner, MD (2) · Henry S. Friedman, MD (1) · Ira Dunkel, MD (1) · Judith K. Sato, MD (1) · Najla El Jurdi, MD (1) · Neyssa M. Marina, MD (1) · Pierre Biron, MD (1) · Stewart Goldman, MD (1)
P30CA008748 (2), P30CA033572 (1)