20 completed, 3 terminated, 3 unknown. 9 Phase 1, 9 Phase 2, 3 Not applicable, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 7, Terminated 2 |
| Phase 2 | 9 | Completed 7, Terminated 2 |
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 3 | 3 | Completed 2, Unknown 1 |
Follow Childhood Germ Cell Tumor: new trials by email Literature Review of Childhood Germ Cell Tumor trials Research Report on Childhood Germ Cell Tumor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal Tumors RNA analysis, gene expression analysis, mutation analysis - Childhood Germ Cell Tumor, Leydig Cell Tumor | Completed | Children's Oncology Group | 50 | 2012-04-01 | 2016-07-14 | |
| Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression DNA methylation analysis, RNA analysis, mutation analysis - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Completed | Children's Oncology Group | 90 | 2011-10-01 | 2016-05-18 | |
| Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors carboplatin, dasatinib, etoposide phosphate - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 / Phase 2 | Terminated | City of Hope Medical Center | 7 | 2008-09-03 | 2023-07-14 |
| Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy sodium thiosulfate, examination - Brain Tumor, Central Nervous System Tumor | Phase 3 | Completed | Children's Oncology Group | 131 | 2008-06-23 | 2023-11-09 |
| Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors carboplatin, etoposide, ifosfamide - Childhood Germ Cell Tumor, Ovarian Cancer | Phase 2 | Completed | Masonic Cancer Center, University of Minnesota | 23 | 2006-12-19 | 2022-05-17 |
| Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01 assessment of therapy complications, quality-of-life assessment - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Unknown | Children's Cancer and Leukaemia Group | 60 | 2006-06-01 | 2013-08-12 | |
| Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors carboplatin, talabostat mesylate, temozolomide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 26 | 2005-12-01 | 2012-03-15 |
| Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors bleomycin sulfate, carboplatin, cisplatin - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 3 | Unknown | Children's Cancer and Leukaemia Group | 105 | 2005-05-01 | 2013-09-17 |
| Electroacupuncture in Treating Delayed Nausea and Vomiting in Patients Receiving Chemotherapy For Newly Diagnosed Childhood Sarcoma, Neuroblastoma, Nasopharyngeal Cancer, Germ Cell Tumors, or Hodgkin Lymphoma electroacupuncture therapy, sham intervention, quality-of-life assessment - Brain Tumors, Central Nervous System Tumors | Not applicable | Completed | Children's Oncology Group | 17 | 2005-04-01 | 2013-05-31 |
| Combination Chemotherapy in Treating Children With Newly Diagnosed Malignant Germ Cell Tumors bleomycin sulfate, filgrastim, cisplatin - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Not applicable | Completed | Children's Oncology Group | 19 | 2004-07-01 | 2013-10-17 |
| Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors carboplatin, etoposide, ifosfamide - Brain Tumor, Central Nervous System Tumors | Phase 2 | Completed | Children's Oncology Group | 104 | 2004-01-01 | 2018-02-14 |
| ABT-751 in Treating Young Patients With Refractory Solid Tumors ABT-751 - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 90 | 2002-03-01 | 2012-03-15 |
| Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy ixabepilone - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Institutes of Health Clinical Center (CC) | 30 | 2001-11-01 | 2012-03-15 |
| Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors arsenic trioxide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 22 | 2001-03-01 | 2015-11-25 |
| Busulfan in Treating Children and Adolescents With Refractory CNS Cancer busulfan - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | Pediatric Brain Tumor Consortium | 28 | 2000-11-01 | 2009-10-07 |
| Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors filgrastim, temozolomide, peripheral blood stem cell transplantation - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 / Phase 2 | Completed | Duke University | 30 | 2000-08-01 | 2013-06-20 |
| Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors O6-benzylguanine, temozolomide - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Completed | National Cancer Institute (NCI) | 2000-06-01 | 2015-04-29 | |
| Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors bleomycin sulfate, amifostine trihydrate, cisplatin - Childhood Germ Cell Tumor, Drug/Agent Toxicity by Tissue/Organ | Phase 2 | Completed | Children's Oncology Group | 27 | 2000-04-01 | 2013-07-04 |
| Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors amifostine trihydrate, busulfan, filgrastim - Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor | Phase 1 | Terminated | Masonic Cancer Center, University of Minnesota | 13 | 1998-11-01 | 2017-11-29 |
| Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell Tumors filgrastim, carboplatin, cyclophosphamide - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Phase 2 | Terminated | UNICANCER | 45 | 1998-03-01 | 2016-06-23 |
Showing 20 of 26. Sign in to see all of them.
Testicular Neoplasms (23) · Ovarian Neoplasms (22) · Teratoma (20) · Ovarian Germ Cell Cancer (18) · Central Nervous System Neoplasms (16) · Sarcoma (14) · Neuroblastoma (13) · Medulloblastoma (12) · Liver Neoplasms (11) · Astrocytoma (10) · Neuroectodermal Tumors, Primitive, Peripheral (10) · Osteosarcoma (10) · Choroid Plexus Neoplasms (9) · Familial ependymoma (9) · Kidney Neoplasms (9)
Neoplasms (26) · Neoplasms by Site (25) · Neoplasms by Histologic Type (24) · Endocrine Gland Neoplasms (23) · Endocrine System Diseases (23) · Genital Diseases (23) · Genital Diseases, Male (23) · Genital Neoplasms, Male (23) · Gonadal Disorders (23) · Male Urogenital Diseases (23) · Neoplasms, Germ Cell and Embryonal (23) · Testicular Diseases (23) · Urogenital Diseases (23) · Urogenital Neoplasms (23) · Adnexal Diseases (22)
Carboplatin (10) · Etoposide (9) · Filgrastim (9) · Peripheral Blood Stem Cell Transplantation (7) · Thiotepa (6) · Bleomycin (5) · Ifosfamide (5) · Cisplatin (4) · Cyclophosphamide (4) · Granulocyte Colony-Stimulating Factor (3) · Radiotherapy (3) · Temozolomide (3) · etoposide phosphate (3) · Amifostine (2) · Busulfan (2)
Children's Oncology Group (8) · Memorial Sloan Kettering Cancer Center (4) · Children's Cancer and Leukaemia Group (3) · National Institutes of Health Clinical Center (CC) (3) · Masonic Cancer Center, University of Minnesota (2) · City of Hope Medical Center (1) · Duke University (1) · National Cancer Institute (NCI) (1) · Pediatric Brain Tumor Consortium (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · UNICANCER (1)
United States (20) · Australia (5) · Canada (5) · Puerto Rico (4) · Ireland (3) · Switzerland (3) · United Kingdom (3) · France (1) · Netherlands (1) · New Zealand (1) · Peru (1)
Brian H. Kushner, MD (2) · Elizabeth Fox, MD (2) · A. Oakhill, MD (1) · Adam Glaser, MD (1) · AeRang Kim, MD (1) · Allen R. Chen, MD, PhD, MHS (1) · Brad H. Pollock, PhD (1) · Dana A. Hill, MD (1) · David R. Freyer, DO, MS (1) · Eric J. Small, MD (1) · Henry S. Friedman, MD (1) · Holly Meany, MD (1) · Ira Dunkel, MD (1) · James F. Amatruda, MD, PhD (1) · John P. Perentesis, MD (1)
PMID 15999362, PMID 16234526, PMID 16533779, PMID 16914576, PMID 17235042, PMID 18281544, PMID 19075272, PMID 19430790, PMID 20044751, PMID 20460632, PMID 27914822, PMID 31545689, PMID 9849694
P30CA008748 (2), P30CA033572 (1)