62 completed, 34 unknown, 33 recruiting, 18 terminated. 92 Not applicable, 36 Phase 2, 8 Phase 3, 7 Phase 1, 5 Early Phase 1.
Follow Chemotherapy-induced Peripheral Neuropathy: new trials by email Literature Review of Chemotherapy-induced Peripheral Neuropathy trials Research Report on Chemotherapy-induced Peripheral Neuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High-concentration Capsaicin Patch for the Prevention of Paclitaxel-induced Peripheral Neuropathy High Concentration Capsaicin Patch (HCCP), Placebo patch - Chemotherapy-induced Peripheral Neuropathy, CIPN - Chemotherapy-Induced Peripheral Neuropathy | Phase 4 | Not yet recruiting | Case Comprehensive Cancer Center | 240 | 2026-10-01 | 2026-09-22 |
| Transcranial Direct Current Stimulation for the Treatment of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Sham Intervention, Survey Administration, Transcranial Direct Current Stimulation - Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphatic System Neoplasm | Not applicable | Recruiting | University of Michigan Rogel Cancer Center | 50 | 2026-09-10 | 2026-10-15 |
| Study of SIR2501 in Solid Tumor Patients Receiving Paclitaxel SIR2501 - Chemotherapy-induced Peripheral Neuropathy | Phase 2 | Recruiting | Sironax USA, Inc. | 18 | 2026-08-21 | 2026-10-09 |
| Exercise and Mindfulness Intervention for Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer Exercise and Mindfulness - Cancer Patients, Chemotherapy-Induced Peripheral Neuropathy | Not applicable | Active not recruiting | Nanjing Medical University | 41 | 2026-07-17 | 2026-09-29 |
| Study of Wenyang Tongbi Formula in the Treatment of Chemotherapy-Induced Polyneuropathy Wenyang Tongbi Granules and Placebo mecobalamin, Mecobalamin with placebo Wenyang Tongbi Granules - Chemotherapy-induced Peripheral Neuropathy | Early Phase 1 | Not yet recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 144 | 2026-07-01 | 2026-06-04 |
| A Single-Arm, Prospective Study of Papaverine for the Treatment of Refractory Peripheral Neuropathy Induced by Taxane-Based Chemotherapy Papaverine hydrochloride injection - Chemotherapy-Induced Peripheral Neuropathy, Refractory Chemotherapy-Induced Peripheral Neuropathy | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 43 | 2026-05-01 | 2026-05-07 |
| CBG/CBD Oil for Chemotherapy-Induced Peripheral Neuropathy CBG/CBD Oil - Chemotherapy-Induced Peripheral Neuropathy | Phase 1 | Recruiting | Milton S. Hershey Medical Center | 12 | 2026-04-03 | 2026-05-11 |
| Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy Scrambler Therapy, Sham/No Intervention - Chemotherapy-induced Peripheral Neuropathy, CIPN - Chemotherapy-Induced Peripheral Neuropathy | Not applicable | Recruiting | Case Comprehensive Cancer Center | 90 | 2026-03-27 | 2026-08-05 |
| A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment Biospecimen Collection, Educational Intervention, Electronic Health Record Review - Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphatic System Neoplasm | Not applicable | Recruiting | University of Michigan Rogel Cancer Center | 50 | 2026-02-23 | 2026-06-25 |
| The Influence of Chemotherapy on Position Sense Questionnaire - Edinburgh Handedness Assessment, Questionnaire - QuickDash, Questionnaire - EORTC QLQ-CIPN20 - CIPN - Chemotherapy-Induced Peripheral Neuropathy, Chemotherapy-Induced Peripheral Neuropathy | Not yet recruiting | KU Leuven | 145 | 2026-02-01 | 2026-01-26 | |
| Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2026 and 2029. Ozone Therapy - Chemotherapy-Induced Peripheral Neuropathy, Radiation Toxicity | Recruiting | Bernardino Clavo, MD, PhD | 120 | 2026-01-14 | 2026-09-23 | |
| VGAIT for Chemotherapy-induced Peripheral Neuropathy Video-Guided Acupuncture Imagery Treatment (VGAIT) - Chemotherapy-induced Peripheral Neuropathy | Not applicable | Recruiting | Massachusetts General Hospital | 20 | 2026-01-06 | 2026-07-22 |
| 8 Weeks vs 12 Weeks Physical Exercise Programmes in Colorectal Cancer Patients Exercise, Physical activity recommendations - Oncology, Chemotherapy-Induced Peripheral Neuropathy | Not applicable | Not yet recruiting | University of Salamanca | 50 | 2026-01-01 | 2026-01-06 |
| Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) VMD-3866 Gel, Placebo Gel - Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain | Phase 2 | Recruiting | VM Therapeutics LLC | 16 | 2025-12-12 | 2026-10-21 |
| Cryocompression for CIPN Paxman Limb Cryocompression System - Chemotherapy-induced Peripheral Neuropathy, Taxane-Induced Peripheral Neuropathy | Not applicable | Recruiting | Dana-Farber Cancer Institute | 50 | 2025-10-22 | 2026-04-15 |
| Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors Biospecimen Collection, Cannabidiol, Dronabinol - Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy | Phase 2 | Recruiting | City of Hope Medical Center | 120 | 2025-10-03 | 2025-12-05 |
| Neurocognitive and Psychological Impact of Chemotherapy in Breast Cancer Patients: A Prospective Observational Study Breast Cancer, Chemotherapy-induced Peripheral Neuropathy | Not yet recruiting | Sohag University | 100 | 2025-10-01 | 2025-09-22 | |
| Tibial Nerve Elastography in Chemotherapy-Induced Neuropathic Pain Shear Wave Elastography Measurement - Chemotherapy-induced Peripheral Neuropathy, Tibial Neuropathy | Not yet recruiting | Ankara Etlik City Hospital | 50 | 2025-09-15 | 2025-07-02 | |
| Compression Stockings to Prevent Peripheral Neuropathy Caused by Antibody-Drug Conjugates in Urothelial Carcinoma Patients Medical-grade compression stocking - Urothelial Carcinoma, Advanced Solid Tumors | Not applicable | Recruiting | Sheng Zhang | 58 | 2025-08-30 | 2025-09-15 |
| Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors Anodyne Therapy System - Cancer, Childhood Cancer | Not applicable | Recruiting | Yale University | 20 | 2025-06-30 | 2026-06-12 |
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Breast Neoplasms (27) · Peripheral Nervous System Diseases (27) · Neoplasms (23) · Neuralgia (15) · Pain (13) · Colorectal Neoplasms (11) · Motor Activity (8) · Chronic Pain (7) · Colonic Neoplasms (4) · Hematologic Neoplasms (4) · Agnosia (3) · Hypesthesia (3) · Multiple Myeloma (3) · Neuropathy, Painful (3) · Ovarian Neoplasms (3)
Nervous System Diseases (50) · Neoplasms by Site (47) · Neoplasms (43) · Neuromuscular Diseases (42) · Pathological Conditions, Signs and Symptoms (33) · Signs and Symptoms (31) · Neurologic Manifestations (30) · Breast Diseases (27) · Skin Diseases (27) · Skin and Connective Tissue Diseases (27) · Digestive System Diseases (17) · Digestive System Neoplasms (17) · Gastrointestinal Diseases (17) · Gastrointestinal Neoplasms (16) · Intestinal Diseases (15)
Acupuncture Therapy (8) · Duloxetine Hydrochloride (7) · Exercise (6) · Transcutaneous Electric Nerve Stimulation (6) · Paclitaxel (5) · Cannabidiol (4) · Surveys and Questionnaires (4) · Capsaicin (3) · Cryotherapy (3) · Electroacupuncture (3) · Sodium Chloride (3) · Standard of Care (3) · Transcranial Direct Current Stimulation (3) · ART123 (2) · Carboplatin (2)
Dana-Farber Cancer Institute (6) · M.D. Anderson Cancer Center (6) · Mayo Clinic (4) · Bernardino Clavo, MD, PhD (3) · City of Hope Medical Center (3) · University Hospital, Clermont-Ferrand (3) · University of Basel (3) · Wake Forest University Health Sciences (3) · Arash Asher, MD (2) · Assiut University (2) · Case Comprehensive Cancer Center (2) · Donna Hammond, PhD (2) · Duke University (2) · Egetis Therapeutics AB (publ) (2) · Izmir Bakircay University (2)
United States (76) · France (11) · Taiwan (10) · China (9) · Belgium (8) · Denmark (8) · Spain (8) · Turkey (Türkiye) (8) · Egypt (7) · Italy (6) · South Korea (6) · Germany (5) · United Kingdom (5) · Austria (4) · Hong Kong (4)
Bernardino Clavo, MD, PhD (2) · Salahadin Abdi (2) · Stefan Carlsson, MD (2) · Alex Molassiotis, PhD (1) · Alexandra Thomas, MD (1) · Alshaymaa Ahmed, MD, PhD (1) · Angela Hansen (1) · Annemarie Coolbrandt, PhD (1) · Arash Asher, MD (1) · Bernardino Clavo, MD, PhyD (1) · Bin Wang (1) · Brendan L McNeish (1)
PMID 23102757, PMID 32379556, PMID 33738491, PMID 15992242, PMID 22105041, PMID 23215625, PMID 24733808, PMID 26357522, PMID 30271455, PMID 31779159, PMID 36308441, PMID 12098632, PMID 12648025, PMID 16213089, PMID 16945171, PMID 17296917, PMID 17572696, PMID 17952647, PMID 17974490, PMID 18428211, PMID 18688212, PMID 19260079, PMID 20805210, PMID 21426373, PMID 21427067, PMID 21575276, PMID 22248793, PMID 23549581, PMID 23733756, PMID 24105751, PMID 24494204, PMID 24687190, PMID 25118789, PMID 25119581, PMID 25635955, PMID 25636304, PMID 25699252, PMID 26032776, PMID 26067584, PMID 26362106, PMID 27013473, PMID 27130723, PMID 28105133, PMID 30250104, PMID 30905173, PMID 31023750, PMID 31196236, PMID 31456070, PMID 32404001, PMID 33403401
P30CA015083 (2), P30CA033572 (2), UG1CA189961 (2), 2014 (1), 2016 (1), 2017 (1), 2019 (1), P30CA012197 (1), P30CA016058 (1), P30CA016672 (1), P30CA138292 (1), R01CA229681 (1), R01CA251470 (1), R21CA208968 (1), R21CA235389 (1)