23 recruiting, 14 completed, 8 unknown, 5 active not recruiting. 36 Not applicable, 8 Phase 2, 3 Early Phase 1, 3 Phase 1, 2 Phase 3.
Follow Cervical Spinal Cord Injury: new trials by email Literature Review of Cervical Spinal Cord Injury trials Research Report on Cervical Spinal Cord Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Rimonabant on Hand Function in Patients With Spinal Cord Injury Rimonabant - Cervical Spinal Cord Injury | Phase 1 / Phase 2 | Active not recruiting | Sinfatin S.L | 8 | 2026-05-13 | 2026-10-21 |
| Low Volume Nose Resistance Breathing Exercise With Incentive Spirometer in Patient With Cervical Spinal Cord Injuries Acapella device plus Incentive Spirometry, conventional respiratory physiotherapy - Cervical Spinal Cord Injury, Cervical Cord Injuries Spinal | Not applicable | Recruiting | Riphah International University | 42 | 2026-05-01 | 2026-06-12 |
| Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI) Connexus Brain-Computer Interface - Amyotrophic Lateral Sclerosis, Neuromuscular Disease | Not applicable | Recruiting | Paradromics | 2 | 2026-03-31 | 2026-04-14 |
| MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System Mind Extender (MindEx) - Paralysis; Quadriplegic, Quadraplegia | Not applicable | Recruiting | Nader Pouratian | 2 | 2026-02-20 | 2026-10-01 |
| Feasibility and Safety of a Combined Augmented Reality and Functional Electrical Stimulation System AR + FES - Cervical Spinal Cord Injury | Early Phase 1 | Recruiting | University Health Network, Toronto | 7 | 2026-01-01 | 2025-12-23 |
| VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration N1 Implant, R1 Robot - Tetraplegia/Tetraparesis, Quadriplegia | Not applicable | Recruiting | Neuralink Corp | 6 | 2025-10-03 | 2025-11-04 |
| GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices N1 Implant, R1 Robot - Tetraplegia/Tetraparesis, Quadriplegia | Not applicable | Recruiting | Neuralink Corp | 7 | 2025-07-31 | 2025-08-17 |
| Spinal Stimulation for Upper Extremity Recovery in the Home Immediate Intervention, Waitlist control - Cervical Spinal Cord Injury | Not applicable | Recruiting | Craig Hospital | 46 | 2025-05-28 | 2026-03-31 |
| UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices N1 Implant, R1 Robot - Tetraplegia/Tetraparesis, Quadriplegia | Not applicable | Recruiting | Neuralink Corp | 10 | 2025-05-09 | 2025-06-05 |
| ExaStim Upper Limb Home Use Clinical Validation Study ExaStim Stimulation System - Cervical Spinal Cord Injury | Not applicable | Completed | Niche Biomedical, Inc. dba ANEUVO | 33 | 2025-03-17 | 2026-04-13 |
| Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury Brief intraoperative electrical stimulation, Temporary Postoperative Peripheral Nerve Stimulation - Cervical Spinal Cord Injury, Cervical Spinal Cord Paralysis | Recruiting | Stanford University | 10 | 2025-02-10 | 2025-02-19 | |
| Robot-assisted vs. Conventional Occupational Therapy of the Upper Limb in Individuals With Cervical Spinal Cord Injury Unilateral robot-assisted therapy (RT), Unilateral conventional occupational therapy (OT) - Cervical Spinal Cord Injury | Not applicable | Recruiting | Swiss Paraplegic Research, Nottwil | 40 | 2025-02-01 | 2026-07-08 |
| Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery Intraoperative stimulation of the cervical spinal cord - Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis | Not applicable | Recruiting | Columbia University | 36 | 2024-12-06 | 2025-11-24 |
| CAN-PRIME: Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices N1 Implant, R1 Robot - Tetraplegia/Tetraparesis, Quadriplegia | Not applicable | Recruiting | Neuralink Corp | 6 | 2024-11-20 | 2025-05-31 |
| EMPOWER Early Feasibility Study: Non-invasive BCI to Control a Wheelchair for People With Paralysis Intervention/Treatment - Neurologic Disorder, Paralysis | Not applicable | Unknown | Synaptrix Labs Inc. | 6 | 2024-11-01 | 2024-01-18 |
| Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord Epidural Spinal Stimulation (ESS) - Spinal Cord Injuries, Cervical Spinal Cord Injury | Not applicable | Recruiting | The Methodist Hospital Research Institute | 12 | 2024-08-06 | 2026-04-08 |
| Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01) BrainGate Neural Interface System - Brainstem Stroke, ALS | Not applicable | Recruiting | Leigh R. Hochberg, MD, PhD. | 6 | 2024-07-22 | 2026-06-25 |
| Rebuilding Inter-limb Transfer in Cervical SCI PCMS + Contralateral Motor Training, PCMS + Rest, Sham PCMS + Contralateral Motor Training - Cervical Spinal Cord Injury | Early Phase 1 | Active not recruiting | The Cleveland Clinic | 17 | 2024-02-15 | 2026-03-24 |
| Nerve Transfer to Improve Function in High Level Tetraplegia Cervical Spinal Cord Injury, Tetraplegia | Recruiting | Washington University School of Medicine | 30 | 2024-02-05 | 2026-03-11 | |
| Precise Robotically IMplanted Brain-Computer InterfacE N1 Implant, R1 Robot - Tetraplegia/Tetraparesis, Quadriplegia | Not applicable | Recruiting | Neuralink Corp | 15 | 2024-01-09 | 2026-01-09 |
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Quadriplegia (25) · Spinal Cord Injuries (21) · Paralysis (10) · Amyotrophic Lateral Sclerosis (9) · Stroke (6) · Brain Stem Infarctions (5) · Brain Injuries, Traumatic (2) · Dysarthria (2) · Motor Neuron Disease (2) · Nervous System Diseases (2) · Paresis (2) · Respiratory Insufficiency (2) · Speech (2) · Spinal Injuries (2) · Wounds and Injuries (2)
Nervous System Diseases (31) · Pathological Conditions, Signs and Symptoms (28) · Signs and Symptoms (28) · Neurologic Manifestations (26) · Central Nervous System Diseases (25) · Trauma, Nervous System (23) · Wounds and Injuries (22) · Spinal Cord Diseases (21) · Paralysis (16) · Brain Diseases (11) · Cardiovascular Diseases (10) · Cerebrovascular Disorders (10) · Vascular Diseases (10) · Metabolic Diseases (9) · Neurodegenerative Diseases (9)
Methods (2) · Blood Flow Restriction Therapy (1) · Brain-Computer Interfaces (1) · Buspirone (1) · Clinical Trials, Phase II as Topic (1) · Clinical Trials, Phase III as Topic (1) · Gene Fusion (1) · Imatinib Mesylate (1) · Rimonabant (1) · SREBP cleavage-activating protein (1) · Surgical Procedures, Operative (1) · Surveys and Questionnaires (1) · Therapeutics (1) · Transcranial Direct Current Stimulation (1) · X-Rays (1)
Neuralink Corp (5) · Washington University School of Medicine (4) · Assiut University (2) · Columbia University (2) · Craig Hospital (2) · Riphah International University (2) · Shirley Ryan AbilityLab (2) · The University of Texas Health Science Center, Houston (2) · University of British Columbia (2) · AO Foundation, AO Spine (1) · Adelante, Centre of Expertise in Rehabilitation and Audiology (1) · Burke Medical Research Institute (1) · Ecole Polytechnique Fédérale de Lausanne (1) · Instituto Nacional de Rehabilitacion (1) · Leigh R. Hochberg, MD, PhD. (1)
United States (34) · Canada (8) · China (2) · Egypt (2) · Pakistan (2) · Switzerland (2) · United Kingdom (2) · Brazil (1) · Germany (1) · Hong Kong (1) · Hungary (1) · India (1) · Mexico (1) · Netherlands (1) · Poland (1)
Ida K Fox, MD (2) · Amanda Kaas, Dr. (1) · Anastasia Zarkou, PT,MS,PhD (1) · Annemie IF Spooren, Dr. (1) · Arjumand Bano, MS (1) · Binash Afzal, PHD* (1) · Daniel C Lu, MD PhD (1) · David Friedenberg, PhD (1) · Dimitry Sayenko, MD, PhD (1) · Ela Plow, PhD (1) · Emily Fox, PT, PhD (1) · Florian Roser, MD (1) · Francisco Ponce, MD (1)
PMID 27130222, PMID 32799791, PMID 35364569, PMID 35901693, PMID 39610700, PMID 41040697, PMID 42367680, PMID 42750660
1OT2OD023854 (1), 2019 (1), 2025 (1), R01NS124224 (1), U01DC017844 (1)