6 completed. 6 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 6 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Brain Edema: new trials by email Literature Review of Brain Edema trials Research Report on Brain Edema
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial of HRS8179 on Brain Swelling After Large Hemispheric Infarction HRS8179, Placebo - Brain Swelling, Large Hemispheric Infarction | Phase 2 | Completed | Beijing Suncadia Pharmaceuticals Co., Ltd | 40 | 2023-04-07 | 2025-01-06 |
| Antisecretory Factor in Primary Glioblastoma 1 Salovum - Glioblastoma, Cerebral Edema | Phase 1 / Phase 2 | Completed | Peter Siesjö | 8 | 2019-09-01 | 2021-04-28 |
| Safety and Efficacy of Glibenclamide Combined With Rt-PA in Acute Cerebral Embolism Glibenclamide, Placebo - Acute Stroke | Phase 2 / Phase 3 | Completed | Nanfang Hospital, Southern Medical University | 306 | 2018-01-01 | 2023-06-12 |
| Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access Intraosseous, Hypertonic saline - Stroke, Intracranial Hypotension | Phase 2 | Completed | Ohio State University | 6 | 2017-04-21 | 2019-07-09 |
| Histamine Glutamate Antagonism in Stroke Diphenhydramine, Pantoprazole, Famotidine - Acute Cerebrovascular Accident, Cerebral Edema | Phase 2 | Completed | University of Florida | 3 | 2014-12-01 | 2015-12-15 |
| Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants Therapeutic Hypothermia, Standard of Care Therapy - Urea Cycle Disorders, Organic Acidemias | Phase 2 | Completed | Uta Lichter-Konecki | 5 | 2007-08-01 | 2015-06-01 |
Stroke (3) · Ischemic Stroke (2) · Argininosuccinic Aciduria (1) · Brain Diseases (1) · Carbamoyl-Phosphate Synthase I Deficiency Disease (1) · Citrullinemia (1) · Coma (1) · Glioblastoma (1) · Hyperammonemia (1) · Intracranial Hypotension (1) · Lethargy (1) · Methylmalonic acidemia (1) · Ornithine Carbamoyltransferase Deficiency Disease (1) · Propionic Acidemia (1)
Central Nervous System Diseases (6) · Nervous System Diseases (6) · Brain Diseases (5) · Cardiovascular Diseases (3) · Cerebrovascular Disorders (3) · Vascular Diseases (3) · Amino Acid Metabolism, Inborn Errors (1) · Astrocytoma (1) · Brain Diseases, Metabolic (1) · Brain Diseases, Metabolic, Inborn (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Consciousness Disorders (1) · Genetic Diseases, Inborn (1) · Genetic Diseases, X-Linked (1) · Glioma (1)
Acetazolamide (1) · Continuous Renal Replacement Therapy (1) · Cool-Down Exercise (1) · Cryotherapy (1) · Dextromethorphan (1) · Dialysis (1) · Diphenhydramine (1) · Famotidine (1) · Glyburide (1) · Hypothermia, Induced (1) · Pantoprazole (1) · Renal Dialysis (1) · Saline Solution, Hypertonic (1) · antisecretory factor (1)
Beijing Suncadia Pharmaceuticals Co., Ltd (1) · Nanfang Hospital, Southern Medical University (1) · Ohio State University (1) · Peter Siesjö (1) · University of Florida (1) · Uta Lichter-Konecki (1)
United States (3) · China (2) · Sweden (1)
Suyue Pan, M.D., Ph.D. (1) · Uta Lichter-Konecki, MD, PhD (1) · Vishnumurthy S Hedna, MD (1)