9 completed, 5 unknown, 1 terminated. 15 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Completed 9, Unknown 5, Terminated 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Barrett Esophagus: new trials by email Literature Review of Barrett Esophagus trials Research Report on Barrett Esophagus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GCC Agonist Signal in the Small Intestine Biopsy, Biospecimen Collection, Esophagogastroduodenoscopy - Barrett Esophagus, Gastroesophageal Reflux Disease | Phase 1 | Completed | University of Wisconsin, Madison | 43 | 2022-11-30 | 2026-04-07 |
| Phase 1B Study of KSP/QRH Dimer for Detection of Neoplasia in the Esophagus KSP/QRH dimer - Barrett Esophagus | Phase 1 | Terminated | University of Michigan | 38 | 2019-05-09 | 2022-11-22 |
| Study of Multiplexed Heptapeptides for Detection of Neoplasia in the Esophagus Multiplexed heptapeptides - Barrett Esophagus | Phase 1 | Completed | University of Michigan | 27 | 2018-05-10 | 2019-08-05 |
| Molecular Fluorescence Endoscopy of (Pre)Malignant Esophageal Lesions IV-administation of EMI-137, Molecular Fluorescence Endoscopy platform - Barrett Esophagus, Esophageal Cancer | Phase 1 | Completed | University Medical Center Groningen | 15 | 2017-02-09 | 2024-04-16 |
| The Safety and Tolerability of Secretrol in Patients With Barrett's Esophagus Secretrol - Barrett's Esophagus | Phase 1 | Unknown | Effexus Pharmaceutical | 13 | 2013-04-01 | 2014-08-04 |
| A In-Vivo Esophageal Protocol for Detection of Neoplasia in the Digestive Tract GI heptapeptide - Barrett's Esophagus | Phase 1 | Completed | University of Michigan | 60 | 2012-07-01 | 2015-10-08 |
| Effect of Zinc on Barrett's Metaplasia zinc gluconate - Barrett's Metaplasia | Phase 1 | Unknown | Main Line Health | 120 | 2011-04-01 | 2013-11-14 |
| Esophageal Protocol for Detection of Neoplasia in the Digestive Tract GI heptapeptide - Barrett Esophagus, Esophageal Adenocarcinoma | Phase 1 | Completed | University of Michigan | 25 | 2011-02-01 | 2012-10-11 |
| Tethered Capsule Endoscope in Screening Participants for Barrett Esophagus questionnaire administration, comparison of screening methods, diagnostic endoscopic procedure - Esophageal Cancer, Precancerous Condition | Phase 1 / Phase 2 | Unknown | US Department of Veterans Affairs | 50 | 2009-05-01 | 2014-01-10 |
| Acid Reflux and Stromal Fibroblasts in Barrett's Esophagus Endoscopy and pH study - Barrett's Esophagus, GERD | Phase 1 | Completed | Mayo Clinic | 16 | 2007-08-01 | 2013-01-17 |
| Erlotinib in Treating Patients With Barrett Esophagus erlotinib hydrochloride, laboratory biomarker analysis, biopsy - Esophageal Cancer, Precancerous Condition | Phase 1 | Unknown | Kansas City Veteran Affairs Medical Center | 25 | 2007-07-01 | 2013-09-17 |
| The Effect of Nexium on Transmucosal Esophageal Leak Esomeprazole (Nexium) 40 mg/day - Reflux, Esophagitis | Phase 1 | Unknown | Main Line Health | 35 | 2006-01-01 | 2010-03-16 |
| Defined Green Tea Catechin Extract in Preventing Esophageal Cancer in Patients With Barrett's Esophagus placebo, defined green tea catechin extract - Barrett Esophagus | Phase 1 | Completed | National Cancer Institute (NCI) | 55 | 2005-11-01 | 2014-09-11 |
| Study To Determine The Maximum Range of Light Doses At Two HPPH Doses With Acceptable Normal Tissue Toxicity For PDT Treatment Of High Grade Dysplasia,CIS or Early Adenocarcinoma In Barrett's Esophagus HPPH - Barrett's Esophagus, CIS | Phase 1 | Completed | Roswell Park Cancer Institute | 18 | 2003-03-01 | 2014-12-02 |
| Study of Photodynamic Therapy (PDT) Using HPPH in Barrett's Esophagus HPPH - Barrett's Esophagus, CIS | Phase 1 | Completed | Roswell Park Cancer Institute | 18 | 2000-08-01 | 2014-01-13 |
Adenocarcinoma Of Esophagus (3) · Esophageal Neoplasms (3) · Gastroesophageal Reflux (3) · Precancerous Conditions (2) · Adenocarcinoma (1) · Esophagitis (1) · Gastrointestinal Neoplasms (1)
Digestive System Diseases (15) · Esophageal Diseases (15) · Gastrointestinal Diseases (15) · Neoplasms (15) · Precancerous Conditions (13) · Digestive System Neoplasms (4) · Neoplasms by Site (4) · Deglutition Disorders (3) · Esophageal Motility Disorders (3) · Gastrointestinal Neoplasms (3) · Head and Neck Neoplasms (3) · Carcinoma (1) · Gastroenteritis (1) · Neoplasms by Histologic Type (1) · Neoplasms, Glandular and Epithelial (1)
2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a (2) · Biopsy (2) · Endoscopy (2) · Endoscopy, Digestive System (2) · Erlotinib Hydrochloride (1) · Esomeprazole (1) · Specimen Handling (1) · gluconic acid (1) · linaclotide (1) · plecanatide (1) · polyphenon E (1)
University of Michigan (4) · Main Line Health (2) · Roswell Park Cancer Institute (2) · Effexus Pharmaceutical (1) · Kansas City Veteran Affairs Medical Center (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · US Department of Veterans Affairs (1) · University Medical Center Groningen (1) · University of Wisconsin, Madison (1)
United States (14) · Netherlands (1)
Hector Nava, MD (2) · Charles Lightdale (1) · Danielle K Turgeon, MD (1) · Danielle Kim Turgeon, M.D. (1) · David S Weinberg (1) · G.M. van Dam, MD, PhD (1) · James M Mullin, Ph.D. (1) · Jason A. Dominitz, MD (1) · Joaquina C. Baranda, MD (1) · Prasad G Iyer, M.D. (1) · Prateek Sharma, M.D. (1) · W.B. Nagengast, MD, PhD, PharmD (1)
N01CN35159 (1), P30CA013696 (1), P30CA014520 (1), UG1CA242635 (1)