Main Line Health: Clinical Trials

24 trials sponsored by Main Line Health, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

10 unknown, 9 completed, 2 active not recruiting, 2 not yet recruiting. 12 Not applicable, 3 Phase 2, 2 Phase 1, 2 Phase 3, 2 Phase 4.

By phase and status

PhaseTrialsStatus
Not applicable12Completed 6, Unknown 3, Not yet recruiting 2, Active not recruiting 1
Phase 23Active not recruiting 1, Completed 1, Unknown 1
Phase 12Unknown 2
Phase 32Completed 1, Recruiting 1
Phase 42Unknown 2

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Postpartum Care in the NICU Multi-Site
Postpartum Doula Support in the NICU - Postpartum, Postpartum Depression (PPD)
Not applicableNot yet recruitingChildren's Hospital of Philadelphia7562027-01-012026-10-14
Postpartum Care in the NICU Multi-Site Breastfeeding
NICU-informed postpartum doula support - Postpartum Complication, Postpartum
Not applicableNot yet recruitingChildren's Hospital of Philadelphia6402027-01-012026-10-19
The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial
40 mg relugolix, 1 mg estradiol, 0.5 mg norethindrone acetate - Endometriosis
Phase 3RecruitingMain Line Health1102024-08-152026-06-12
Artificial Intelligence (AI) Enabled, Cloud-based ECG Diagnostic Solution (ZBPro) Feasibility Testing
Cardiac Monitoring - Arrhythmias, Cardiac
UnknownZBeats INC752023-08-302023-09-26
Comparison of Left Bundle Branch Area Versus Right Ventricular Septal Pacing in Patients With High-degree Conduction Disease After Transcatheter Aortic Valve Replacement (Left Bundle BRAVE)
Right ventricular septal pacing followed by left bundle branch area pacing, Left bundle branch area pacing followed by right ventricular septal pacing - Complete Heart Block, High Degree Second Degree Atrioventricular Block
Not applicableActive not recruitingMain Line Health462022-12-282024-12-10
I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients
Remdesivir, Imatinib Mesylate, Dexamethasone - COVID-19
Phase 2Active not recruitingQuantumLeap Healthcare Collaborative15002020-07-312026-03-16
Effect of Hemp-CBD on Patients With CIPN
Hemp-based CBD, Placebo oral tablet - Chemotherapy-induced Peripheral Neuropathy, Colorectal Cancer Stage II
Phase 2UnknownMain Line Health562020-05-272022-09-01
PECS Block in Partial Mastectomy for Postoperative Pain Control
Pectoral Nerve Block, Surgery without Nerve Block - Breast Cancer, Postoperative Pain
Not applicableUnknownMain Line Health1302019-09-012020-02-20
A Comparison of IV Versus PO Acetaminophen Postoperatively for Opioid Consumption After Cesarean Section
Acetaminophen, Placebos - Postoperative Pain, Cesarean Section
Phase 4UnknownMain Line Health1302019-08-222020-02-28
BCAA Supplementation for Concussion
Branched Chain Amino Acids, Placebo solution - Brain Concussion
Phase 2CompletedChildren's Hospital of Philadelphia422014-01-012024-05-14
Photodynamic Therapy (PDT) Oncology Registry
Registry - Lung Cancer, Esophageal
UnknownMain Line Health10002012-11-012018-08-24
Transvaginal Ultrasound Training for Obstetrics and Gynecology Residents
Transvaginal Ultrasound Educational DVD - Ovarian Cysts
Not applicableCompletedThomas Jefferson University572012-09-012016-09-08
17% Salicylate Versus 17% Salicylate-Ethyl Pyruvate for Plantar Foot Warts
17% Salicylate with ethyl pyruvate, Salicylates - Warts
Phase 4UnknownGrossman, Michael, D.P.M.1002011-11-012012-10-23
Effect of Zinc on Barrett's Metaplasia
zinc gluconate - Barrett's Metaplasia
Phase 1UnknownMain Line Health1202011-04-012013-11-14
Educational Interventions for Chronic Obstructive Pulmonary Disease (COPD) Self-management in Ethno-cultural Communities
Group one, Group two, Group three - Chronic Obstructive Pulmonary Disease (COPD)
Not applicableCompletedUniversity of British Columbia1202011-01-012017-11-28
Optimizing Left Ventricular Lead To Improve Cardiac Output
Doppler flow measurement, standard implantation of the LV lead - Ischemic Congestive Cardiomyopathy, Dilated Cardiomyopathy
Not applicableCompletedAnn Marie Chikowski122010-12-012022-08-30
The Use of Bioimpedance to Determine Pre-Clinical Lymphedema in the Post-Operative Breast Cancer Patient
Garment Sleeve - Breast Cancer
Not applicableUnknownMain Line Health2002010-07-012012-01-30
Cesarean Trial of Staples vs. Sutures
Staples, Suture - Cesarean Section, Wound Complications
Not applicableCompletedThomas Jefferson University7462010-06-012019-11-26
Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries
Dexamethasone, Aprepitant, Placebo Dexamethasone - Nausea, Vomiting
Not applicableUnknownMain Line Health502009-02-012009-02-04
IDO2 Genetic Status Informs the Neoadjuvant Efficacy of Chloroquine (CQ) in Brain Metastasis Radiotherapy
Chloroquine diphosphate - Brain Metastasis
Not applicableCompletedMain Line Health202008-12-012015-04-08

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Conditions studied

Breast Neoplasms (3)  ·  Barrett Esophagus (2)  ·  Pain (2)  ·  Pain, Postoperative (2)  ·  Patient Satisfaction (2)  ·  Adenocarcinoma (1)  ·  Aortic Valve Stenosis (1)  ·  Arrhythmias, Cardiac (1)  ·  Brain Concussion (1)  ·  Brain Neoplasms (1)  ·  Breast Feeding (1)  ·  COVID-19 (1)  ·  Cardiomyopathy, Dilated (1)  ·  Colorectal Neoplasms (1)  ·  Depression, Postpartum (1)

Interventions

Dexamethasone (2)  ·  1-phenyl-3,3-dimethyltriazene (1)  ·  Acetaminophen (1)  ·  Amino Acids (1)  ·  Aprepitant (1)  ·  Celecoxib (1)  ·  Cyclosporine (1)  ·  Cyproheptadine (1)  ·  Doulas (1)  ·  Esomeprazole (1)  ·  Estradiol (1)  ·  Famotidine (1)  ·  Imatinib Mesylate (1)  ·  Nerve Block (1)  ·  Norethindrone Acetate (1)

Countries

United States (23)  ·  Canada (1)

Top investigators

Dmitri Chamchad, MD (2)  ·  Heather H Burris, MD, MPH (2)  ·  A. Dhanya Mackeen, MD, MPH (1)  ·  Albert DeNittis, MD (1)  ·  Ali Keramati, MD (1)  ·  Andrea V Barrio, MD (1)  ·  Arnold Markowitz, MD (1)  ·  Daniel B. Ornt (1)  ·  Derek W Russell, MD (1)  ·  Dusan Kocovic, MD (1)  ·  James M Mullin, Ph.D. (1)  ·  Jordan Klebanoff, MD (1)  ·  Kathleen D Liu, MD (1)  ·  Laura Esserman, MD (1)  ·  Marisa Weiss, MD (1)

Results publications

PMID 12490682, PMID 22270285, PMID 22524979, PMID 24807325, PMID 26348166, PMID 27536093, PMID 34473343, PMID 36883141, PMID 37888839, PMID 39525828, PMID 39592213, PMID 40462830, PMID 42799508

NIH funding

R01HD121939 (1), R41HL160317 (1), U01DK046109 (1), U01DK046114 (1), U01DK046126 (1), U01DK046140 (1), U01DK046143 (1), U01DK049240 (1), U01DK049241 (1), U01DK049242 (1), U01DK049243 (1), U01DK049244 (1), U01DK049249 (1), U01DK049252 (1), U01DK049254 (1)