23 completed, 7 unknown, 2 withdrawn, 1 active not recruiting. 15 Not applicable, 9 Phase 2, 6 Phase 3, 3 Phase 1, 3 Phase 4.
Follow gluconic acid: new trials by email Literature Review of gluconic acid trials Research Report on gluconic acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect Of Botox In Patients With Gummy Smile With And Without Zinc And Phytase Supplementation. zinc gluconate 50 mg with phytase supplement 176mg (800FTU), zinc gluconate 50 mg - Excessive Gingival Display | Not applicable | Unknown | Cairo University | 36 | 2024-06-01 | 2024-09-23 |
| The Effect of Platelet-rich Plasma Nasal Injection in the Treatment of Traumatic Olfactory Dysfunction platelet-rich plasma combined with hyaluronic acid, Zinc Gluconate 10 MG Oral Tablet, 4 bottles of phenyl ethyl alcohol, lemon, eucalyptus, and clove oil - Traumatic Olfactory Nerve Injury With Anosmia (Diagnosis), Effect of Drug | Phase 3 | Unknown | Taichung Veterans General Hospital | 80 | 2024-03-20 | 2024-03-04 |
| Effect of Zinc on Glucose Homeostasis Zinc Gluconate 30 MG, Placebo - Prediabetic State, Hyperglycemia | Phase 4 | Recruiting | University of Maryland, Baltimore | 200 | 2024-02-16 | 2026-07-10 |
| Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib Amivantamab IV, Amivantamab SC, Lazertinib - Carcinoma, Non-Small-Cell Lung | Phase 2 | Active not recruiting | Janssen Research & Development, LLC | 305 | 2024-02-16 | 2026-09-25 |
| Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia Zinc gluconate supplement, Botulinum toxin type A - Spasmodic Dysphonia | Phase 1 / Phase 2 | Completed | University of Florida | 32 | 2023-08-01 | 2026-07-27 |
| The Exploration of the Regulatory Effect of Zinc on Intestinal Flora in Healthy Adults Zinc Gluconate - Healthy | Not applicable | Completed | The Seventh Affiliated Hospital, Southern Medical University | 56 | 2023-03-01 | 2024-10-09 |
| Gandouling in the Treatment of Wilson's Disease Gandouling - Wilson's Disease | Phase 4 | Unknown | Jun Li | 240 | 2023-01-01 | 2024-02-09 |
| Zinc Intervention in Elderly for Prevention of Pneumonia Zinc gluconate - Zinc Deficiency | Phase 2 / Phase 3 | Completed | Tufts University | 105 | 2022-05-03 | 2024-07-30 |
| Vitamin D and Zinc Supplementation for Improving Treatment Outcomes Among COVID-19 Patients in India Vitamin D3 (cholecalciferol), Zinc (zinc gluconate), Zinc (zinc gluconate) & Vitamin D (cholecalciferol) - COVID-19 | Phase 3 | Completed | Harvard School of Public Health (HSPH) | 181 | 2021-04-22 | 2022-09-19 |
| RCT,Double Blind, Placebo to Evaluate the Effect of Zinc and Ascorbic Acid Supplementation in COVID-19 Positive Hospitalized Patients in BSMMU zinc gluconate and ascorbic acid - Covid19 | Not applicable | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 50 | 2020-10-01 | 2020-09-22 |
| Zinc Supplementation and Behçet's Syndrome Zinc gluconate, Placebo - Behcet Syndrome | Not applicable | Completed | Tabriz University of Medical Sciences | 50 | 2020-08-22 | 2021-11-04 |
| Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation Ascorbic Acid, Zinc Gluconate, Ascorbic Acid and Zinc Gluconate - COVID, Corona Virus Infection | Not applicable | Completed | The Cleveland Clinic | 214 | 2020-04-08 | 2021-02-16 |
| Impact of Zinc and Vitamin D3 Supplementation on the Survival of Aged Patients Infected With COVID-19 Zinc gluconate, 25-OH cholecalciferol - SARS-CoV 2 | Not applicable | Withdrawn | University Hospital, Lille | 2020-04-01 | 2021-03-11 | |
| Zinc Effect on Inflammation and Cardiovascular Risk in HIV Zinc Gluconate, Placebo - Inflammation, Cardiovascular Diseases | Early Phase 1 | Completed | University Hospitals Cleveland Medical Center | 95 | 2020-01-22 | 2025-06-12 |
| The Individual Therapy for Patients With Wilson's Disease DMPS, Penicillamine, DMSA - Wilson's Disease | Early Phase 1 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 400 | 2019-03-15 | 2019-05-21 |
| Effects of Oral Zinc Gluconate Among Acne Vulgaris Patients Zinc gluconate, Adapalene 0.003 MG/MG / Benzoyl Peroxide 0.025 MG/MG Topical Gel [Epiduo], Placebo - Acne Vulgaris | Phase 4 | Completed | East Avenue Medical Center, Philippines | 23 | 2018-12-21 | 2022-05-11 |
| Dietary Supplementation With Butyrate in Individuals With Liver Steatosis and Metabolic Syndrome Food for special medical purposes with calcium butyrate, zinc gluconate and vitamin D3, Placebo - NAFLD, Metabolic Syndrome | Not applicable | Completed | University of Bologna | 50 | 2017-03-01 | 2024-05-03 |
| Zinc Supplementation and Cardiovascular Risk in HIV Zinc gluconate - HIV, Inflammation | Not applicable | Completed | Grace McComsey | 52 | 2016-09-01 | 2022-02-11 |
| Fluid Therapy During Brain Tumor Resection in Children balanced crystalloid solution (components: sodium chloride, sodium gluconate, sodium acetate, potassium chloride and magnesium chloride), 0.9% sodium chloride - Brain Neoplasms | Phase 2 | Completed | Federal University of São Paulo | 53 | 2015-08-01 | 2017-11-14 |
| Zinc Supplementation in Cirrhotic Patients zinc gluconate, Placebo, Nutritional education - Dysgeusia, Liver Cirrhosis | Not applicable | Unknown | Fundación Clínica Médica Sur | 70 | 2015-04-01 | 2019-02-15 |
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COVID-19 (4) · Inflammation (4) · Hepatolenticular Degeneration (2) · Acid-Base Imbalance (1) · Acne Vulgaris (1) · Adenocarcinoma (1) · Alagille Syndrome (1) · Alcohol Drinking (1) · Barrett Esophagus (1) · Behcet Syndrome (1) · Biliary Atresia (1) · Brain Neoplasms (1) · Canavan Disease (1) · Carcinoma, Non-Small-Cell Lung (1) · Cardiovascular Diseases (1)
All India Institute of Medical Sciences (1) · Assistance Publique - Hôpitaux de Paris (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Boston Medical Center (1) · Brooklyn ImmunoTherapeutics, LLC (1) · Cairo University (1) · Centro Universitario de Lavras (1) · Chang Gung Memorial Hospital (1) · East Avenue Medical Center, Philippines (1) · Federal University of São Paulo (1) · Fundación Clínica Médica Sur (1) · Grace McComsey (1) · Harvard School of Public Health (HSPH) (1) · Janssen Research & Development, LLC (1) · Jun Li (1)
United States (9) · China (4) · Brazil (3) · India (3) · Egypt (2) · Philippines (2) · Taiwan (2) · Argentina (1) · Bangladesh (1) · France (1) · Germany (1) · Iran (1) · Italy (1) · Malaysia (1) · Mexico (1)
Caroline Sevin, MD, PhD (1) · Claudio Borghi (1) · Douglas C Fonseca, Ms (1) · Dr. Dilip Mahalanabis, MBBS (1) · Grace A McComsey, MD, FIDSA (1) · Grace McComsey, MD (1) · James Heubi (1) · Jeffrey S. Moyer, MD (1) · Jeffrey Samet, MD, MA, MPH (1) · Matthew S. Freiberg, MD, MSc (1) · Mawda M Hussain, Bachelor (1)
PMID 12064356, PMID 12183720, PMID 15784740, PMID 16002461, PMID 16194720, PMID 20539208, PMID 21284052, PMID 21840002, PMID 22057678, PMID 22109700, PMID 22571226, PMID 24259556, PMID 29663871, PMID 32383748, PMID 33576820, PMID 33757560, PMID 33757717, PMID 34291813, PMID 35413570, PMID 36038172, PMID 36062970, PMID 36366796, PMID 37560461, PMID 38450236, PMID 39610253, PMID 40538652, PMID 40923969, PMID 42876725
R21AT009153 (2), 2023 (1), R34HL153277 (1), U01AA021989 (1)