69 completed, 30 unknown, 20 recruiting, 7 active not recruiting. 140 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 140 | Completed 69, Unknown 30, Recruiting 20, Active not recruiting 7, Not yet recruiting 6, Terminated 4, Withdrawn 4 |
Follow Ataxia: new trials by email Literature Review of Ataxia trials Research Report on Ataxia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Can Acute Photobiomodulation Improve Balance and Cognition in Individuals With Ataxia: a Pilot Feasibility Placebo Randomized Controlled Trial. Photobiomodulation, Sham photobiomodulation - Ataxia | Not applicable | Not yet recruiting | University of Central Lancashire | 20 | 2027-01-01 | 2026-09-22 |
| Bilateral Anodal Cerebellar tDCS for Multidomain Dysfunctions in Patients With Multiple Sclerosis Bilateral Cerebellar Transcranial Direct Current Stimulation (ctDCS), Sham Bilateral Cerebellar tDCS - Multiple Sclerosis | Not applicable | Not yet recruiting | University of Sharjah | 40 | 2026-09-01 | 2026-04-29 |
| Optimizing Parameters of Transcranial Temporal Interference Stimulation for Spinocerebellar Ataxia Type 3 Transcranial Temporal Interference Stimulation (tTIS) - Spinocerebellar Ataxia Type 3 | Not applicable | Not yet recruiting | First Affiliated Hospital of Fujian Medical University | 24 | 2026-08-07 | 2026-09-01 |
| Individualized Neuro-Modulation Paired With Cerebellar Therapy Therapy - Cerebellar Ataxia, Cerebellar Diseases | Not applicable | Recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 30 | 2026-06-30 | 2026-06-11 |
| Robotic Neurorehabilitation in Patients With Ataxia Robot-Assisted Neurorehabilitation, Conventional Neurorehabilitation - Ataxia - Other | Not applicable | Active not recruiting | Somogy Megyei Kaposi Mór Teaching Hospital | 100 | 2026-06-02 | 2026-07-29 |
| Interposed Nucleus aDBS for Ataxia Deep Brain Stimulation - Spinocerebellar Ataxia (SCA), Spinocerebellar Ataxia Type 6 | Not applicable | Recruiting | University of Florida | 5 | 2026-06-02 | 2026-07-20 |
| Balloon Inflation in Biofeedback Inflating anorectal catheter balloon to defecatory desired volume during push manoeuvres in biofeedback therapy., No intervention - Constipation, Chronic Constipation | Not applicable | Completed | Hull University Teaching Hospitals NHS Trust | 8 | 2026-05-13 | 2026-09-22 |
| Deep Brain Stimulation for Spinocerebellar Ataxia Deep Brain Stimulation (DBS) - Spinocerebellar Ataxia (SCA), Spinocerebellar Ataxia Type 6 | Not applicable | Recruiting | University of California, San Francisco | 5 | 2026-04-27 | 2026-07-13 |
| At Home Use of Stimulation Suits for Managing MS Symptoms electro-stimulation suit, Usual Care - Multiple Sclerosis, MS (Multiple Sclerosis) | Not applicable | Recruiting | Daphne Kos | 70 | 2026-03-16 | 2026-10-08 |
| Use of a New Smartphone Application to Determine Changes in Eyeblink Conditioning From Home Training in Individuals With Spinocerebellar Ataxia Aerobic Training, Balance Training - Spinocerebellar Ataxias | Not applicable | Withdrawn | Columbia University | 2026-01-01 | 2026-05-07 | |
| Autosomal Dominant Spinocerebellar Ataxias and Social Cognition tests - Autosomal Dominant Spinocerebellar Ataxia (SCA1, 2,3,6,7,27B) | Not applicable | Recruiting | University Hospital, Angers | 160 | 2025-12-09 | 2026-07-20 |
| Impact of Foot Orthoses on Gait in Individuals With Ataxia Home wearing schedule - Ataxia | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 20 | 2025-11-21 | 2026-07-22 |
| Ophthalmological Disorders in Dominant Spinal-cerebellar Ataxias Neurological assessment, Ophthalmological assessment - Spinocerebellar Ataxia | Not applicable | Recruiting | University Hospital, Montpellier | 60 | 2025-10-10 | 2025-11-20 |
| rTMS for Cerebellar Ataxia in Children Repetitive Transcranial Magnetic Stimulation, Sham Repetitive Transcranial Magnetic Stimulation - Cerebellar Ataxia | Not applicable | Not yet recruiting | The University of Hong Kong | 20 | 2025-10-01 | 2025-10-08 |
| Cawthorne-Cooksey Exercises and Frenkel Exercises on Balance and Coordination in Stroke Cawthorne-Cooksey Exercises, Frenkel Exercises - Stroke, Stroke (CVA) or TIA | Not applicable | Completed | Riphah International University | 22 | 2025-07-01 | 2026-07-24 |
| Motor-Cognitive Training , Cognitive Performance and Balance Motor-Cognitive Training Program, Regular Physical education classes - Coordination Impairment, Children | Not applicable | Completed | Princess Nourah Bint Abdulrahman University | 50 | 2025-06-30 | 2026-10-27 |
| Assistive Devices and Gait in Persons With Ataxia Walking with different walkers - Ataxia - Other | Not applicable | Completed | University of Texas Southwestern Medical Center | 20 | 2025-05-22 | 2026-09-28 |
| Effects of Cerebellar tACS-iTBS in Ataxia Real (real iTBS/tACS + exergaming), Sham (sham iTBS/tACS + exergaming) - Ataxia | Not applicable | Recruiting | I.R.C.C.S. Fondazione Santa Lucia | 30 | 2025-05-01 | 2026-02-17 |
| Evaluation of Urinary Dysfunction in CANVAS Patients Evaluation of urinary dysfunction in patients with CANVAS - Cerebellar Ataxia, Neuropathy | Not applicable | Recruiting | Centre Hospitalier Universitaire de Nice | 40 | 2025-03-21 | 2025-03-26 |
| Efficacy of Cerebellar Transcranial Magnetic Stimulation to Treat Hereditary Spinocerebellar Ataxias navigated iTBS (Intermittent theta-burst stimulation) targeting the cerebellum - Spinocerebellar Ataxias | Not applicable | Not yet recruiting | Xijing Hospital | 80 | 2025-03-20 | 2025-03-27 |
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Cerebellar Ataxia (43) · Spinocerebellar Ataxias (39) · Machado-Joseph Disease (10) · Ataxia Telangiectasia (9) · Motor Activity (8) · Multiple Sclerosis (8) · Spinocerebellar Degenerations (7) · Stroke (7) · Gait Ataxia (6) · Neurodegenerative Diseases (6) · Parkinson Disease (6) · Cerebellar Diseases (5) · Constipation (5) · Movement Disorders (5)
Dyskinesias (138) · Neurologic Manifestations (138) · Nervous System Diseases (137) · Pathological Conditions, Signs and Symptoms (112) · Signs and Symptoms (107) · Central Nervous System Diseases (101) · Brain Diseases (99) · Cerebellar Diseases (83) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (62) · Genetic Diseases, Inborn (60) · Heredodegenerative Disorders, Nervous System (51) · Neurodegenerative Diseases (50) · Spinal Cord Diseases (49) · Cerebellar Ataxia (44)
Transcranial Magnetic Stimulation (7) · Transcranial Direct Current Stimulation (5) · Blood Specimen Collection (4) · Deep Brain Stimulation (4) · Biofeedback, Psychology (3) · Control Groups (2) · Exercise Therapy (2) · Physical Therapy Modalities (2) · Trehalose (2) · Weights and Measures (2) · 6-chloro-2-(1-piperazinyl)pyrazine (1) · Ambroxol (1) · Asparaginase (1) · Athletic Tape (1) · Betaine (1)
Chang Gung University (5) · Columbia University (5) · Hacettepe University (5) · Cairo University (4) · Hugo W. Moser Research Institute at Kennedy Krieger, Inc. (4) · Johann Wolfgang Goethe University Hospital (4) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (3) · IRCCS Eugenio Medea (3) · Johns Hopkins University (3) · University of Florida (3) · Augusta University (2) · Centre Hospitalier Universitaire de Nice (2) · Changhua Christian Hospital (2) · First Affiliated Hospital of Fujian Medical University (2) · Hasan Kalyoncu University (2)
United States (36) · France (11) · Italy (9) · Turkey (Türkiye) (9) · Taiwan (7) · Brazil (6) · Egypt (6) · Canada (5) · China (5) · Germany (5) · United Kingdom (4) · Pakistan (3) · Spain (3) · Belgium (2) · Chile (2)
Barbara Borroni, MD (4) · Alberto Benussi, MD (3) · Amy J Bastian, PhD, PT (3) · Stefan Zielen, Prof. Dr. (3) · Cherie Marvel, PhD (2) · Alex Martino Cinnera, PhD (1) · Alison Behrman, PhD (1) · Alvaro Pascual-Leone, MD, PhD (1) · Amanda S Therrien, PhD (1) · Andres Lozano, MD (1) · Arthur L. Beaudet, MD (1) · Ben Parrell, Ph.D. (1)
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R01HD040289 (2), K23NS121518 (1), P2CHD086844 (1), R01DC016275 (1), R01DC017091 (1), R01DK057048 (1), R01HD075813 (1), R21NS085491 (1), R21NS094946 (1), R21NS125546 (1)