6 recruiting, 5 unknown, 3 not yet recruiting, 2 completed. 17 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Recruiting 6, Unknown 5, Not yet recruiting 3, Completed 2, Enrolling by invitation 1 |
Follow Arteritis: new trials by email Literature Review of Arteritis trials Research Report on Arteritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Vunakizumab and Ivarmacitinib in the Treatment of Active Takayasu's Arteritis Vanakizumab, Ivarmacitinib, Prednisone - Takayasu Arteritis (TAK) | Phase 4 | Not yet recruiting | Chinese SLE Treatment And Research Group | 180 | 2026-04-01 | 2026-03-05 |
| Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases Dengue 1,2,3,4 (attenuated) vaccine - Rheumatoid Arthritis (RA), Juvenile Idiopathic Arthritis (JIA) | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 477 | 2026-03-16 | 2026-07-20 |
| Effect of Pirfenidone on TA Fibrosis Pirfenidone Capsules, Placebo - Takayasu Arteritis | Phase 4 | Not yet recruiting | Shanghai Zhongshan Hospital | 92 | 2025-12-20 | 2026-01-08 |
| The Efficacy and Safety of Deucravacitinib in Takayasu's Arteritis Deucravacitinib, Adalimumab - Takayasu Arteritis (TAK) | Phase 4 | Not yet recruiting | Chinese SLE Treatment And Research Group | 50 | 2025-06-15 | 2025-06-10 |
| Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases Shingrix, vaccination with 2 doses of Shingrix vaccine - Systemic Vasculitis, Spondylarthropathies | Phase 4 | Enrolling by invitation | Region Skane | 240 | 2024-12-17 | 2025-01-10 |
| A Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's Arteritis Prednisone, Methotrexate, Tocilizumab - Takayasu Arteritis | Phase 4 | Recruiting | Shanghai Zhongshan Hospital | 124 | 2024-06-28 | 2024-10-17 |
| Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency Hydrocortisone, Placebo for hydrocortisone - Adrenal Insufficiency, Polymyalgia Rheumatica | Phase 4 | Recruiting | Marianne Christina Klose | 250 | 2022-06-07 | 2026-03-16 |
| Hydrocortisone and Placebo in Patients With Symptoms of Adrenal Insufficiency After Cessation of Glucocorticoid Treatment Hydrocortisone, Placebo - Adrenal Insufficiency, Polymyalgia Rheumatica (PMR) | Phase 4 | Recruiting | Marianne Andersen | 100 | 2022-02-01 | 2025-12-22 |
| Comparison of Adalimumab and Tofacitinib in the Treatment of Active Takayasu Arteritis Adalimumab Injection, Tofacitinib 5 MG - Takayasu Arteritis | Phase 4 | Unknown | Chinese SLE Treatment And Research Group | 100 | 2022-01-05 | 2023-07-24 |
| Comparison of Tofacitinib and Methotrexate in Takayasu's Arteritis Tofacitinib, Methotrexate - Takayasu Arteritis | Phase 4 | Recruiting | Shanghai Zhongshan Hospital | 76 | 2021-11-01 | 2024-10-15 |
| A Pilot Study in Severe Patients With Takayasu Arteritis. Tocilizumab, Adalimumab - Takayasu Arteritis, Tocilizumab | Phase 4 | Recruiting | Shanghai Zhongshan Hospital | 40 | 2020-03-01 | 2021-08-10 |
| Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients Methotrexate Tablets, Tofacitinib tablet - Takayasu Arteritis, Methotrexate | Phase 4 | Unknown | Shanghai Zhongshan Hospital | 130 | 2020-03-01 | 2020-06-12 |
| Tocilizumab Plus a Short Prednisone Taper for GCA Tocilizumab, Prednisone - Giant Cell Arteritis | Phase 4 | Completed | Massachusetts General Hospital | 30 | 2018-11-28 | 2022-12-02 |
| Tocilizumab Dose-tapering and Interruption in Patients With Giant Cell Arteritis Achieving the Clinical Remission. Tocilizumab - Giant Cell Arteritis | Phase 4 | Unknown | Hospital of Prato | 15 | 2015-01-01 | 2017-08-10 |
| Steroids Pharmacokinetics and the Response to Prednisone Therapy in Giant Cell Arteritis Prednisone therapy and pharmacokinetic - Giant Cell Arteritis | Phase 4 | Unknown | University Hospital, Caen | 150 | 2009-07-01 | 2014-04-09 |
| Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years prednisone, methylprednisolone,cyclophosphamides, Cyclophosphamide, Azathioprine,prednisone,methylprednisolone, Mycophenolate mofetil,methotrexate - Vasculitis, Wegener's Granulomatosis | Phase 4 | Completed | Assistance Publique - Hôpitaux de Paris | 108 | 2005-07-01 | 2011-09-12 |
| CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis Factors azathioprine, cyclophosphamide - Polyarteritis Nodosa, Microscopic Polyangiitis | Phase 4 | Unknown | Hospices Civils de Lyon | 124 | 1996-07-01 | 2006-11-16 |
Takayasu Arteritis (9) · Giant Cell Arteritis (6) · Microscopic Polyangiitis (3) · Polymyalgia Rheumatica (3) · Adrenal Insufficiency (2) · Arthritis, Juvenile (2) · Arthritis, Psoriatic (2) · Granulomatosis with Polyangiitis (2) · Polyarteritis Nodosa (2) · Vasculitis (2) · Antiphospholipid Syndrome (1) · Aortitis (1) · Arthritis (1) · Arthritis, Rheumatoid (1) · Axial Spondyloarthritis (1)
Cardiovascular Diseases (17) · Skin Diseases (17) · Skin Diseases, Vascular (17) · Skin and Connective Tissue Diseases (17) · Vascular Diseases (17) · Vasculitis (15) · Aortic Diseases (10) · Aortic Arch Syndromes (9) · Autoimmune Diseases (9) · Brain Diseases (9) · Central Nervous System Diseases (9) · Cerebrovascular Disorders (9) · Immune System Diseases (9) · Nervous System Diseases (9)
Adalimumab (4) · Methotrexate (4) · Prednisone (4) · tocilizumab (4) · tofacitinib (4) · Azathioprine (2) · Cyclophosphamide (2) · Glucocorticoids (2) · Hydrocortisone (2) · Methylprednisolone (1) · Mycophenolic Acid (1) · Vaccination (1) · Vaccines (1) · deucravacitinib (1) · ivarmacitinib (1)
Shanghai Zhongshan Hospital (5) · Chinese SLE Treatment And Research Group (3) · Assistance Publique - Hôpitaux de Paris (1) · Hospices Civils de Lyon (1) · Hospital of Prato (1) · Marianne Andersen (1) · Marianne Christina Klose (1) · Massachusetts General Hospital (1) · Region Skane (1) · University Hospital, Caen (1) · University of Sao Paulo General Hospital (1)
China (7) · Denmark (2) · France (2) · Brazil (1) · Italy (1) · Sweden (1) · Switzerland (1) · United States (1)
Lindi Jiang, PhD (3) · Ana D Fernandes, MA (1) · Lindi Jiang, Ph.D., M.D. (1) · Marianne Klose, MD, PhD (1) · Marianne S Andersen (1) · Ulla Feldt-Rasmussen, Professor (1) · Xiaofeng Zeng, MD (1) · Xinping Tian, MD (1)
PMID 14558057, PMID 22674883, PMID 25153486, PMID 25693055, PMID 25697557, PMID 37540159, PMID 38251564, PMID 41638742, PMID 42276802
2008 (1), 2023 (1)