89 completed, 49 recruiting, 38 unknown, 17 not yet recruiting. 33 Phase 2, 29 Phase 3, 25 Not applicable, 17 Phase 4, 8 Phase 1.
Follow Arteritis: new trials by email Literature Review of Arteritis trials Research Report on Arteritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Aspirin for the Prevention of Ischemic Complications in Giant Cell Arteritis Acetyl Salicylic Acid (ASA), Placebo - Giant Cell Arteritis (GCA), Acute Coronary Syndrome (ACS) | Phase 3 | Not yet recruiting | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | 120 | 2027-10-01 | 2026-10-30 |
| Reducing Arterial Inflammation Using Eplerenone and Statins in HIV Eplerenone, Placebo - HIV (Human Immunodeficiency Virus), Cardiovascular Diseases (CVD) | Phase 2 / Phase 3 | Not yet recruiting | Massachusetts General Hospital | 124 | 2027-03-01 | 2026-10-23 |
| Long-Axial Field of View (LAFOV) [18F]FDG PET/CT Imaging in Large Vessel Vasculitis (LVV): Protocol Optimisation Study. [18F]FDG Long-Axial Field of View (LAFOV)-PET/CT, CT Angiogram, MR Angiogram - Large Vessel Vasculitis, Takayasu Arteritis | Not applicable | Not yet recruiting | Imperial College London | 18 | 2026-12-01 | 2026-10-16 |
| Mapping B-cell Biology Across the Cardiovascular Territories of Giant Cell Arteritis: Towards a New Therapeutic Approach (RituxiMAP GCA) Zirconium Zr 89 labelled rituximab - Giant Cell Arteritis (GCA) | Not yet recruiting | University of Edinburgh | 30 | 2026-10-01 | 2026-06-16 | |
| Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research Pericarditis, Tako-TSUBO Cardiomyopathy | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 300 | 2026-09-01 | 2026-08-10 | |
| Monitoring Disease Activity in Patients With Takayasu Arteritis With the OMERACT Takayasu Ultrasound Score (OTUS) Takayasu Arteritis (TAK) | Not yet recruiting | IRCCS San Raffaele | 100 | 2026-07-01 | 2026-05-11 | |
| Treatment for Giant Cell Arteritis With Tocilizumab and 8 as Compared to 26 Weeks of Prednisone Prednisone - Giant Cell Arteritis (GCA) | Phase 3 | Not yet recruiting | Insel Gruppe AG, University Hospital Bern | 178 | 2026-07-01 | 2026-05-01 |
| Kinetics of C-Reactive Protein in Giant Cell Arteritis Following Glucocorticoid Initiation: A Pilot Study (GIDEON) Blood tests to measure CRP - Giant Cell Arteritis (GCA) | Not applicable | Not yet recruiting | University Hospital, Limoges | 40 | 2026-06-22 | 2026-07-22 |
| Bosentan in the Treatment of Giant Cell Arteritis Bosentan, Glucocorticoids - Giant Cell Arteritis (GCA) | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 40 | 2026-06-01 | 2026-05-06 |
| Disease Activity Monitoring in Patients With Giant Cell Arteritis Study Giant Cell Arteritis (GCA) | Recruiting | University of Aarhus | 175 | 2026-05-06 | 2026-08-31 | |
| Early Temporal Dynamics of Optic Nerve Sheath Diameter After Therapy in GCA Optic Nerve Sheath Ultrasound, Temporal artery ultrasound, Bloodwork : CRP and ESR - Giant Cell Arteritis, Temporal Arteritis | Recruiting | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | 60 | 2026-05-01 | 2026-10-21 | |
| Efficacy and Safety of Vunakizumab and Ivarmacitinib in the Treatment of Active Takayasu's Arteritis Vanakizumab, Ivarmacitinib, Prednisone - Takayasu Arteritis (TAK) | Phase 4 | Not yet recruiting | Chinese SLE Treatment And Research Group | 180 | 2026-04-01 | 2026-03-05 |
| Phase II Interventional Study Evaluating Efficacy and Safety of Secukinumab in Active Severe Takayasu Patients Secukinumab, Standard of Care (SOC) - Takayasu Arteritis, Large Vessel Vasculitis | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 52 | 2026-04-01 | 2026-03-27 |
| Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases Dengue 1,2,3,4 (attenuated) vaccine - Rheumatoid Arthritis (RA), Juvenile Idiopathic Arthritis (JIA) | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 477 | 2026-03-16 | 2026-07-20 |
| The VGR GCA Cohort: Ultrasound, Biopsy and Biomarkers - Novel Methods for Diagnosis, Monitoring and Prognosis in Giant Cell Arteritis. Giant Cell Arteritis (GCA) | Recruiting | Vastra Gotaland Region | 340 | 2026-03-01 | 2026-04-15 | |
| Upadacitinib in Giant Cell Arteritis (GCA) With Active Large-vessel Involvement. Giant Cell Arteritis (GCA) | Not yet recruiting | Groupe français d'étude des Maladies Inflammatoires de loeil | 80 | 2026-03-01 | 2026-01-21 | |
| Halo Sign Vanishing Time After Steroids Outbreak in GCA Patients Doppler Ultrasound - Giant Cell Arteritis (GCA), Doppler Ultrasound | Not applicable | Recruiting | Centre Hospitalier le Mans | 64 | 2026-02-27 | 2026-07-17 |
| Study of the Association Between Sacroiliitis/Axial Spondylarthritis and Giant Cell Arteritis/ Polymyalgia Rheumatica Description of population - Giant Cell Arteritis (GCA), Spondylarthritis | Not yet recruiting | Hôpital NOVO | 10 | 2026-02-01 | 2026-02-06 | |
| Orbital Vascular Inflammation in Ischemic Optic Neuropathy and Giant Cell Arteritis Positron Emission Tomography / Magnetic Resonance Imaging - Giant Cell Arteritis (GCA), Ischemic Optic Neuropathy | Recruiting | Copenhagen University Hospital, Rigshospitalet | 122 | 2026-01-14 | 2026-05-07 | |
| Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell Arteritis Tocilizumab, Discontinue Tocilizumab - Giant Cell Arteritis (GCA) | Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 78 | 2026-01-05 | 2026-08-10 |
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Giant Cell Arteritis (146) · Takayasu Arteritis (76) · Vasculitis (29) · Polymyalgia Rheumatica (25) · Polyarteritis Nodosa (22) · Granulomatosis with Polyangiitis (21) · Arthritis, Rheumatoid (20) · Microscopic Polyangiitis (18) · Churg-Strauss Syndrome (16) · Behcet Syndrome (13) · Lupus Erythematosus, Systemic (11) · Arthritis, Juvenile (10) · Arthritis, Psoriatic (10) · IgA Vasculitis (10)
Vascular Diseases (216) · Cardiovascular Diseases (212) · Skin Diseases (207) · Skin and Connective Tissue Diseases (207) · Skin Diseases, Vascular (206) · Vasculitis (191) · Nervous System Diseases (160) · Immune System Diseases (157) · Brain Diseases (156) · Central Nervous System Diseases (156) · Cerebrovascular Disorders (155) · Autoimmune Diseases (153) · Autoimmune Diseases of the Nervous System (149) · Vasculitis, Central Nervous System (141)
tocilizumab (19) · Prednisone (14) · Methotrexate (9) · Adalimumab (7) · Infliximab (7) · Glucocorticoids (6) · secukinumab (6) · tofacitinib (6) · Adrenal Cortex Hormones (5) · Blood Specimen Collection (5) · Cyclophosphamide (5) · Abatacept (4) · Azathioprine (4) · Surveys and Questionnaires (4) · upadacitinib (4)
Assistance Publique - Hôpitaux de Paris (11) · Centre Hospitalier Universitaire Dijon (10) · University of Pennsylvania (10) · Shanghai Zhongshan Hospital (8) · Massachusetts General Hospital (6) · Chinese SLE Treatment And Research Group (5) · University of Bonn (5) · University of South Florida (5) · Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal (4) · Groupe français d'étude des Maladies Inflammatoires de loeil (4) · Insel Gruppe AG, University Hospital Bern (4) · Novartis Pharmaceuticals (4) · University Hospital, Brest (4) · University Hospital, Caen (4) · University Hospital, Limoges (4)
France (63) · United States (49) · Canada (26) · China (25) · Germany (23) · Denmark (19) · United Kingdom (18) · Italy (14) · Switzerland (14) · Spain (11) · Belgium (10) · Netherlands (10) · Australia (9) · Sweden (9) · Turkey (Türkiye) (9)
Peter A. Merkel, MD, MPH (8) · Peter A Merkel, MD, MPH (5) · Lindi Jiang, PhD (4) · Amanda M. Terry, MA (3) · Raashid A Luqmani, DM FRCP (3) · Xinping Tian, MD (3) · Ann Morgan (2) · Jean-Paul Makhzoum, MD (2) · Megan Clowse, MD, MPH (2) · Peter C. Grayson, MD (2) · Peter Merkel, MD, MPH (2) · Salome Kristensen, MD, PhD (2)
PMID 26952547, PMID 28745999, PMID 32866179, PMID 10068416, PMID 14558057, PMID 16221103, PMID 16914703, PMID 17332971, PMID 17407214, PMID 17470830, PMID 17557758, PMID 19955046, PMID 20054700, PMID 20055902, PMID 21743987, PMID 21873264, PMID 22674883, PMID 23528439, PMID 23653652, PMID 23897775, PMID 24046471, PMID 24106211, PMID 24189842, PMID 24529335, PMID 24574239, PMID 24675165, PMID 24891881, PMID 25153486, PMID 25396066, PMID 25592534, PMID 25693055, PMID 25697557, PMID 25902790, PMID 26090367, PMID 26304483, PMID 26631773, PMID 26712071, PMID 27236507, PMID 27924855, PMID 27940595, PMID 27980877, PMID 28133925, PMID 28133931, PMID 28405470, PMID 28629556, PMID 28678392, PMID 28756037, PMID 28780030, PMID 29016646, PMID 29086462
U54AR057319 (7), 2018 (4), 2023 (3), 2016 (2), 2017 (2), 2019 (2), 2008 (1), 2015 (1), 2025 (1), 268200700036C-5-0-1 (1), R01AR084199 (1)