11 completed, 5 recruiting, 5 unknown, 1 terminated. 4 Phase 2, 2 Phase 4, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Terminated 1, Unknown 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
| Not applicable | 1 | Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Polyarteritis Nodosa: new trials by email Literature Review of Polyarteritis Nodosa trials Research Report on Polyarteritis Nodosa
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biologics in Refractory Vasculitis: A Trial of Biologic Therapy for Refractory Primary Non-ANCA Associated Vasculitis Rituximab, Infliximab, Tocilizumab - Giant Cell Arteritis, Takayasu Arteritis | Phase 2 | Terminated | Cambridge University Hospitals NHS Foundation Trust | 22 | 2021-07-14 | 2025-06-17 |
| Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis Naltrexone Hydrochloride, Placebo Comparator - Eosinophilic Granulomatosis With Polyangiitis (EGPA), Churg-Strauss Syndrome (CSS) | Phase 2 | Completed | University of Pennsylvania | 60 | 2019-02-04 | 2026-01-22 |
| Journey of Patients With Vasculitis From First Symptom to Diagnosis Online Questionnaire - Vasculitis, Systemic Vasculitis | Completed | University of Pennsylvania | 456 | 2018-01-11 | 2018-06-06 | |
| Clinical Transcriptomics in Systemic Vasculitis (CUTIS) Cryoglobulinemic Vasculitis (CV), Drug-induced Vasculitis | Recruiting | Peter Merkel | 50 | 2017-01-01 | 2026-01-22 | |
| VCRC Tissue Repository Aortitis, Cutaneous Vasculitis | Recruiting | University of Pennsylvania | 1000 | 2016-11-01 | 2026-01-22 | |
| Vasculitis Pregnancy Registry Online questionnaires - Vasculitis, Behcet's Disease | Recruiting | University of Pennsylvania | 100 | 2015-11-01 | 2026-01-23 | |
| Impact of Vasculitis on Employment and Income online questionnaire - Vasculitis, Systemic Vasculitis | Completed | University of South Florida | 426 | 2015-06-01 | 2016-01-28 | |
| Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis Takayasu's Arteritis, Giant Cell Arteritis | Recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 4000 | 2014-09-29 | 2026-10-22 | |
| VCRC Patient Contact Registry Patient-Reported Data Validation Study Behcet's Disease, Churg-Strauss Syndrome | Completed | University of South Florida | 198 | 2014-05-01 | 2019-10-16 | |
| Pediatric Vasculitis Initiative Wegeners Granulomatosis (Granulomatosis With Polyangiitis), Microscopic Polyangiitis | Unknown | University of British Columbia | 1600 | 2013-01-01 | 2023-11-30 | |
| Educational Needs of Patients With Systemic Vasculitis Behcet's Disease, Churg-Strauss Syndrome | Completed | University of South Florida | 386 | 2012-03-01 | 2014-07-15 | |
| Vasculitis Illness Perception (VIP) Study Wegener Granulomatosis, Microscopic Polyangiitis | Completed | University of South Florida | 707 | 2011-10-01 | 2014-07-15 | |
| Reproductive Health in Men and Women With Vasculitis Giant Cell Arteritis, Takayasu's Arteritis | Completed | University of South Florida | 467 | 2011-02-01 | 2014-06-26 | |
| American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification Criteria for Primary Systemic Vasculitis Wegener's Granulomatosis, Microscopic Polyangiitis | Unknown | University of Oxford | 3588 | 2011-01-01 | 2016-08-19 | |
| One-Time DNA Study for Vasculitis Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Giant Cell Arteritis | Recruiting | University of Pennsylvania | 1000 | 2010-10-01 | 2026-01-22 | |
| Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) corticosteroid and azathioprine, corticosteroid and placebo - MPA, PAN or EGPA With FFS=0 | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 114 | 2008-05-01 | 2025-09-12 |
| Determining Disease Activity Biomarkers in Individuals With Polyarteritis Nodosa Polyarteritis Nodosa | Completed | University of Pennsylvania | 107 | 2006-04-01 | 2022-07-12 | |
| Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years prednisone, methylprednisolone,cyclophosphamides, Cyclophosphamide, Azathioprine,prednisone,methylprednisolone, Mycophenolate mofetil,methotrexate - Vasculitis, Wegener's Granulomatosis | Phase 4 | Completed | Assistance Publique - Hôpitaux de Paris | 108 | 2005-07-01 | 2011-09-12 |
| Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases anti-thymocyte globulin, cyclophosphamide, cyclosporine - Purpura, Schoenlein-Henoch, Graft Versus Host Disease | Not applicable | Unknown | Fairview University Medical Center | 10 | 2000-03-01 | 2005-06-24 |
| CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis Factors azathioprine, cyclophosphamide - Polyarteritis Nodosa, Microscopic Polyangiitis | Phase 4 | Unknown | Hospices Civils de Lyon | 124 | 1996-07-01 | 2006-11-16 |
Showing 20 of 22. Sign in to see all of them.
Microscopic Polyangiitis (17) · Churg-Strauss Syndrome (16) · Granulomatosis with Polyangiitis (16) · Takayasu Arteritis (15) · Giant Cell Arteritis (13) · Vasculitis (12) · IgA Vasculitis (10) · Behcet Syndrome (7) · Vasculitis, Central Nervous System (7) · Cryoglobulinemia, Familial Mixed (5) · Systemic Vasculitis (4) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (2) · Polychondritis, Relapsing (2) · Anemia, Hemolytic, Autoimmune (1)
Arteritis (22) · Cardiovascular Diseases (22) · Skin Diseases (22) · Skin and Connective Tissue Diseases (22) · Vascular Diseases (22) · Skin Diseases, Vascular (21) · Autoimmune Diseases (20) · Brain Diseases (20) · Central Nervous System Diseases (20) · Cerebrovascular Disorders (20) · Nervous System Diseases (20) · Immune System Diseases (19) · Hemic and Lymphatic Diseases (18) · Systemic Vasculitis (18) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (17)
Cyclophosphamide (4) · Azathioprine (3) · Methotrexate (2) · Methylprednisolone (2) · Prednisone (2) · Adrenal Cortex Hormones (1) · Antilymphocyte Serum (1) · Cyclosporine (1) · Filgrastim (1) · Infliximab (1) · Lamivudine (1) · Mycophenolic Acid (1) · Naltrexone (1) · Rituximab (1) · tocilizumab (1)
University of Pennsylvania (6) · University of South Florida (5) · Assistance Publique - Hôpitaux de Paris (2) · Cambridge University Hospitals NHS Foundation Trust (1) · Fairview University Medical Center (1) · Hospices Civils de Lyon (1) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Peter Merkel (1) · University of British Columbia (1) · University of Oxford (1) · University of Parma (1)
United States (17) · Canada (7) · France (3) · United Kingdom (3) · Denmark (2) · Germany (2) · India (2) · Italy (2) · Switzerland (2) · Turkey (Türkiye) (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · China (1)
Peter A. Merkel, MD, MPH (5) · Peter A Merkel, MD, MPH (4) · Amanda M. Terry, MA (3) · Megan Clowse, MD, MPH (2) · Peter C. Grayson, MD (2) · Peter Merkel, MD, MPH (2) · Antoine Sreih, MD (1) · Arne Slungaard (1) · Carlo Buzio, MD (1) · Christian Pagnoux, MD, MPH, MSc (1) · Colin Ross, PhD (1) · David Cabral, MBBS (1) · David Jayne (1) · Dirk Foell, MD (1) · Janice Mooney, M.Sc. (1)
PMID 25153486, PMID 25693055, PMID 27940595, PMID 28678392, PMID 29016646, PMID 31056661, PMID 31649025, PMID 31785185, PMID 33544969, PMID 35612893, PMID 38825350, PMID 38825354
U54AR057319 (4)