30 completed, 10 unknown, 9 recruiting, 1 not yet recruiting. 27 Not applicable, 1 Early Phase 1, 1 Phase 1, 1 Phase 2, 1 Phase 3.
Follow Appendicitis Acute: new trials by email Literature Review of Appendicitis Acute trials Research Report on Appendicitis Acute
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Endotracheal Tube Cuff Pressure Management on Postoperative Sore Throat in Pediatric Laparoscopic Appendectomy Pressure Transducer, Traditional Palpation Method - Appendicitis Acute, Postoperative Sore Throat, Cough, Hoarseness | Not applicable | Recruiting | Ankara Etlik City Hospital | 60 | 2026-06-30 | 2026-07-07 |
| Effect Of Specimen Extraction Site And Local Anesthesia On Postoperative Pain In Laparoscopic Appendectomy Port-site local anesthesia infiltration, Port-Site Saline Infiltration (Placebo) - Appendectomy, Laparoscopic, Appendicitis Acute | Not applicable | Recruiting | YUNUS YÜKSEL | 300 | 2026-04-24 | 2026-09-17 |
| Diagnosis of Abdominal Pain Using RNA Levels: The NATURAL Study TruNAV, an RNA-based blood test for host immune activation by infections - Intra Abdominal Infections, Appendicitis Acute | Recruiting | True Bearing Diagnostics, Inc. | 1000 | 2026-04-17 | 2026-05-12 | |
| First Appendectomy Using Revolve Surgical Robotic Arm Revolve Surgical System - RSS - Appendicitis Acute | Not applicable | Not yet recruiting | Unity Health Toronto | 3 | 2026-04-01 | 2026-03-06 |
| Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial. outpatient surgery, Hospitalization - Appendicitis Acute, Gangrenous Appendicitis | Not applicable | Recruiting | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 122 | 2025-11-01 | 2026-04-21 |
| Differences In Microbiota Profiles Of Pediatric Appendicitis Cases Appendectomy - Appendicitis Acute, Disbiosis | Not applicable | Completed | Istanbul University | 50 | 2025-08-18 | 2026-10-06 |
| Prevention of Postoperative Hernias in Emergency Surgery Incarcerated Hernia, Appendicitis Acute | Recruiting | Jan Kochanowski University | 500 | 2025-06-01 | 2025-06-15 | |
| Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis Discharge on oral antibiotics - Appendicitis Acute, Appendicitis Perforated | Not applicable | Recruiting | Cedars-Sinai Medical Center | 20 | 2025-04-21 | 2025-04-29 |
| The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary Care Diagnostic strategy - Appendicitis Acute, Acute Abdomen in Children | Not applicable | Recruiting | University Medical Center Groningen | 566 | 2025-03-06 | 2026-07-13 |
| Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients Intra-Abdominal Infections, Intestinal Obstruction | Completed | Ain Shams University | 100 | 2025-03-04 | 2025-12-24 | |
| Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients Infection-Prediction Algorithm - Appendectomy, Appendicitis | Not applicable | Recruiting | Ann & Robert H Lurie Children's Hospital of Chicago | 500 | 2025-01-07 | 2026-05-13 |
| Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis PERIsign examination - Appendicitis Acute, Appendicitis | Not applicable | Completed | STB INN AB | 40 | 2024-03-15 | 2024-09-19 |
| Clinical Study of PEG Bowel Preparation in Appendectomy Patients Bowel Preparation with Polyethylene Glycol (PEG) Laxatives - Appendicitis, Appendicitis Acute | Recruiting | Huaping Xie | 10 | 2024-02-23 | 2026-03-17 | |
| Low-dose Contrast Media for Low-kVp Abdomen CT Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT - Appendicitis Acute | Not applicable | Terminated | Bohyun Kim | 109 | 2023-12-21 | 2026-09-09 |
| Laparoscopic Versus Open Appendectomy Prospective Randomized Control Study Open appendectomy, Conventional Lap appendectomy - Appendicitis Acute | Not applicable | Unknown | Abanoub Atif Fawzy | 70 | 2023-11-01 | 2023-07-18 |
| Comparison of Ketorolac at Three Doses in Children With Acute Pain Ketorolac Tromethamine - Acute Pain, Abdominal Pain | Phase 3 | Completed | Hamilton Health Sciences Corporation | 171 | 2023-06-01 | 2025-07-09 |
| A Comparative Study of CCI, EmSFI, and FTRST Scoring Systems Frailty assessment - One Hundred Patients Aged 65 and Older Who Underwent Emergency General Surgical Interventions, Clinical Utility of These Scoring Systems | Completed | Dr. Lutfi Kirdar Kartal Training and Research Hospital | 100 | 2023-03-14 | 2025-07-16 | |
| Efficacy of LigaSure Versus Harmonic Scalpel US in Laparoscopic Appendectomy in Management of Acute Appendicitis laparoscopic appendectomy - Appendicitis Acute | Completed | Zagazig University | 60 | 2023-01-01 | 2025-07-29 | |
| Diagnostic Importance of the Circulating Human Leucine-rich α-2-glycoprotein in Acute Appendicitis in Pediatric Patients Blood specimen collection, Saliva specimen collection - Appendicitis Acute | Unknown | KBC Split | 90 | 2021-10-15 | 2022-04-07 | |
| Online Field Test of an Appendicitis Decision Support Tool Appendicitis Decision Support Tool, Control Infographic - Appendicitis Acute | Not applicable | Completed | University of Washington | 194 | 2021-10-06 | 2022-02-02 |
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Appendicitis (52) · Abdominal Pain (3) · Abdomen, Acute (2) · Agnosia (2) · Intraabdominal Infections (2) · Pain (2) · Peritonitis (2) · Acute Pain (1) · COVID-19 (1) · Cholecystitis, Acute (1) · Cough (1) · Diverticulitis (1) · Dysbiosis (1) · Gastroenteritis (1) · Gastrointestinal Neoplasms (1)
Cecal Diseases (52) · Digestive System Diseases (52) · Gastrointestinal Diseases (52) · Intestinal Diseases (52) · Gastroenteritis (51) · Infections (51) · Intraabdominal Infections (50) · Pathological Conditions, Signs and Symptoms (14) · Signs and Symptoms (11) · Neurologic Manifestations (10) · Pain (5) · Nervous System Diseases (4) · Pathologic Processes (4) · Signs and Symptoms, Digestive (4) · Peritoneal Diseases (3)
Appendectomy (7) · Hospitalization (2) · Ambulatory Surgical Procedures (1) · Blood Specimen Collection (1) · Bupivacaine (1) · Device Approval (1) · Diagnostic Imaging (1) · Ketorolac (1) · Ketorolac Tromethamine (1) · Laxatives (1) · Levobupivacaine (1) · Polyethylene Glycols (1) · Transducers, Pressure (1)
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (2) · Abanoub Atif Fawzy (1) · Ain Shams University (1) · Amasya University (1) · Ankara Etlik City Hospital (1) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Assiut University (1) · Association Francaise de Chirurgie (1) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (1) · Bohyun Kim (1) · Boston Children's Hospital (1) · Cedars-Sinai Medical Center (1) · Centre Hospitalier Universitaire de Besancon (1) · Clinical Hospital Centre Zagreb (1)
Turkey (Türkiye) (8) · Croatia (5) · Egypt (5) · United States (5) · Spain (3) · Canada (2) · Denmark (2) · France (2) · South Korea (2) · Austria (1) · China (1) · Czechia (1) · Estonia (1) · Italy (1) · Netherlands (1)
Aamir Ali, M.D. (1) · Adam Whitley, MUDr. (1) · Ahmed H Hussein, MD, PhD (1) · Ahmed M Ahmed, MD. (1) · Arun Jayaraman, PT, PhD (1) · Bartosz Molasy, MD, PhD (1) · Bohyun Kim, MD, PhD (1) · Chih-Yang Hsiao, M.D. (1) · Claus A Bertelsen, Ph.D. (1) · David R Flum, MD, MPH (1) · Edgar Lipping, MD (1) · Fizan Abdullah, MD, PhD (1)
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