6 completed, 2 recruiting, 2 terminated, 1 unknown. 6 Not applicable, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 2, Terminated 2, Recruiting 1, Unknown 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow Laxatives: new trials by email Literature Review of Laxatives trials Research Report on Laxatives
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Oral Laxative Use Before Colorectal Surgery on Intraoperative Surgical Difficulty Oral Laxative, Rectal Enema - Colorectal Diseases, Mechanical Bowel Preparation | Not applicable | Recruiting | Van Training and Research Hospital | 60 | 2026-05-22 | 2026-09-15 |
| Different Bowel Preparations in Magnetically Controlled Capsule Endoscopy Polyethylene Glycol Electrolytes Powder (II), Low residue diet, Normal diet - Magnetically Controlled Capsule Endoscopy, Bowel Preparation | Not applicable | Unknown | Qilu Hospital of Shandong University | 375 | 2024-03-14 | 2024-03-19 |
| Clinical Study of PEG Bowel Preparation in Appendectomy Patients Bowel Preparation with Polyethylene Glycol (PEG) Laxatives - Appendicitis, Appendicitis Acute | Recruiting | Huaping Xie | 10 | 2024-02-23 | 2026-03-17 | |
| Effects of Changing Intestinal Transit Time on Gut Microbial Composition and Metabolism Diet + laxative, Diet only - Diet, Healthy, Metabolic Disease | Not applicable | Completed | University of Copenhagen | 22 | 2023-10-03 | 2025-03-19 |
| Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation taVNS, Laxative Agent - Chronic Constipation | Not applicable | Terminated | Air Force Military Medical University, China | 106 | 2023-01-03 | 2024-07-10 |
| Retrospective, Uncontrolled Cohort Study on the Therapy of Chronic Megalon colon surgery, Laxatives - Megacolon | Completed | Theresienkrankenhaus und St. Hedwig-Klinik GmbH | 67 | 2020-05-07 | 2022-04-27 | |
| Breathlessness Exertion and Morphine Sulphate Placebo, Morphine Sulfate, Plus laxative (Docusate with senna) - Chronic Obstructive Pulmonary Disease, Dyspnea | Phase 3 | Completed | Flinders University | 171 | 2016-08-08 | 2020-02-11 |
| Evaluation of the Triple Management Program in the Management of Functional Chronic Constipation in Children laxatives - Constipation Chronic Idiopathic | Not applicable | Completed | Minia University | 180 | 2016-03-01 | 2023-10-13 |
| A Single-arm, Study to Assess the Effect and Tolerability of Standardised Laxative Therapy (SLT) for the Reversal of Opioid-induced Constipation (OIC). Laxative - Opioid Induced Constipation | Phase 4 | Completed | Mundipharma Research GmbH & Co KG | 117 | 2013-10-01 | 2016-05-04 |
| Educational-Medical-Behavioral Treatment of Fecal Incontinence Education, Fiber supplements, Laxatives or anti-diarrheals - Fecal Incontinence | Not applicable | Terminated | University of North Carolina, Chapel Hill | 31 | 2013-01-01 | 2017-02-17 |
| Comparison of TCM and Laxatives for Adults With Chronic Constipation Chinese herbal formula (CCH1), Duphalac - Chronic Constipation | Phase 3 | Completed | National Taiwan University Hospital | 93 | 2008-07-01 | 2010-05-04 |
Constipation (3) · Appendicitis (1) · Dyspnea (1) · Fecal Incontinence (1) · Megacolon (1) · Metabolic Diseases (1) · Opioid-Induced Constipation (1) · Pulmonary Disease, Chronic Obstructive (1)
Air Force Military Medical University, China (1) · Flinders University (1) · Huaping Xie (1) · Minia University (1) · Mundipharma Research GmbH & Co KG (1) · National Taiwan University Hospital (1) · Qilu Hospital of Shandong University (1) · Theresienkrankenhaus und St. Hedwig-Klinik GmbH (1) · University of Copenhagen (1) · University of North Carolina, Chapel Hill (1) · Van Training and Research Hospital (1)
China (3) · Australia (1) · Denmark (1) · Germany (1) · New Zealand (1) · Sweden (1) · Taiwan (1) · Turkey (Türkiye) (1) · United States (1)
Chien-Hsun Huang, MD, MSc (1) · Daniel Schmitz, PhD, MD (1) · David C Currow, MD, PhD (1) · William E Whitehead, PhD (1)
PMID 21382575, PMID 28716797, PMID 32375747, PMID 32765039, PMID 34138761, PMID 36413230, PMID 38477675, PMID 39260392, PMID 40015533, PMID 40269943, PMID 40359320