11 completed, 7 recruiting, 4 unknown, 3 not yet recruiting. 16 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Recover@Home Postoperative Follow-up Study Recovery@home - Hernia, Inguinal, Hernia, Femoral | Not applicable | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 194 | 2027-03-01 | 2026-07-20 |
| Hospital Based Continuous Patient Monitoring System Consumer Wearable Device Vital Sign Measurement - Trauma, Appendectomy | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 250 | 2026-11-01 | 2026-10-08 |
| Video-Based Grading of Intraoperative Adverse Events in Pediatric Laparoscopic Appendectomy Laparoscopic appendectomy - Appendicitis, Acute, Appendectomy | Recruiting | Ahmet Burak Doğan, MD | 80 | 2026-09-01 | 2026-09-04 | |
| Quality of Life and Pain After Appendectomy in Children Chronic Pain, Postoperative, Quality of Life | Not yet recruiting | Kocaeli City Hospital | 231 | 2026-07-01 | 2026-06-05 | |
| Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy Bupivacain, Normal Saline - Appendectomy | Phase 1 | Recruiting | Sardar Umer Rehman | 60 | 2025-12-16 | 2026-02-24 |
| Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain Management Nalbuphine Injection, Next Generation Sequencing, whole exome sequencing - Cholecystectomy, Hernia, Abdominal | Phase 2 / Phase 3 | Recruiting | Dr. Asma Abdus Salam | 263 | 2025-09-01 | 2026-04-15 |
| The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia caudal block using dexmedetomidine with bupivacaine, caudal block with bupivacaine - Appendectomy, Pediatric | Not applicable | Recruiting | Ain Shams University | 60 | 2025-08-01 | 2026-05-06 |
| Effect of Probiotic's Consumption on Several Markers in Perforated Appendix Patients With Diffuse Peritonitis Lactobacillus plantarum sp Probiotic, Placebo Group - Appendicitis With Perforation, Appendectomy | Not applicable | Active not recruiting | Universitas Padjadjaran | 50 | 2025-08-01 | 2026-03-31 |
| Ultrasound-Guided Transversalis Fascia Plane Block Versus Quadratus Lumborum Plane Block for Analgesia After Appendectomy in Pediatrics Transversalis Fascia Plane Block group, Quadratus Lumborum Plane Block group - Transversalis Fascia Plane Block, Quadratus Lumborum Block | Not applicable | Enrolling by invitation | Tanta University | 70 | 2025-06-30 | 2026-06-01 |
| A Global Prospective Cohort Study on Outcomes of Appendicectomy for Appendicitis Appendicectomy - Appendicitis, Appendectomy | Recruiting | University of Birmingham | 14000 | 2025-02-03 | 2025-04-02 | |
| Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients Infection-Prediction Algorithm - Appendectomy, Appendicitis | Not applicable | Recruiting | Ann & Robert H Lurie Children's Hospital of Chicago | 500 | 2025-01-07 | 2026-05-13 |
| Closure of the Appendiceal Stump appendectomy - Appendectomy | Not applicable | Unknown | Sezgin Topuz | 48 | 2024-08-01 | 2024-06-05 |
| Effect of Music Listening on Early Mobility in Children Undergoing Appendectomy Music Group Implementation Before surgery, children were asked whether they enjoyed listening to music and what styles of music they liked. - Appendectomy, Child | Not applicable | Completed | Akdeniz University | 68 | 2024-01-01 | 2025-08-19 |
| The Effect of Foot Reflexology on Patients Undergoing Appendectomy Surgery Foot Reflexology - Nursing, Pain | Not applicable | Completed | Bartın Unıversity | 120 | 2023-01-01 | 2024-05-09 |
| RICA (ERAS) Pathway Adherence and Early Discharge Feasibility After Urgent Uncomplicated Appendectomy (APENERAS) Acute Appendicitis, Appendectomy | Completed | Hospital Galdakao-Usansolo | 193 | 2022-12-07 | 2026-02-10 | |
| The Effect of Cartoons Watched Before Surgery on Children's Fear Level divert attention - Preoperative, Cartoon | Not applicable | Completed | Ayse Sonay Turkmen, Prof.Dr | 116 | 2021-01-14 | 2025-01-10 |
| Appendectomy by Low Impact Laparoscopy vs Routine Laparoscopy : a Randomized Prospective Monocentric Trial Conventional group, Low impact laparoscopy group - Appendicitis, Appendectomy | Not applicable | Completed | Centre Hospitalier Universitaire de Nice | 50 | 2021-01-12 | 2026-03-24 |
| Complications After Appendectomy in Elderly Appendectomy | Completed | Zagazig University | 585 | 2020-04-01 | 2025-01-22 | |
| TAP Block or Wound Infiltration for Laparoscopic Pediatric Appendectomy: a Pilot Study TAP Block, LIA local infiltration, General anesthesia - Appendectomy, Laparoscopy | Not applicable | Unknown | Ospedale di Circolo - Fondazione Macchi | 20 | 2020-03-30 | 2020-03-04 |
| Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter? laparoscopic lavage - Appendicitis, Appendectomy | Recruiting | Niguarda Hospital | 1067 | 2019-10-01 | 2026-04-16 |
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Appendicitis (10) · Pain, Postoperative (3) · Abdominal Pain (1) · Abscess (1) · Agnosia (1) · Appendiceal Neoplasms (1) · Chronic Pain (1) · Gallbladder Neoplasms (1) · Hernia, Abdominal (1) · Hernia, Femoral (1) · Hernia, Inguinal (1) · Hernia, Umbilical (1) · Hernia, Ventral (1) · Infections (1) · Intraoperative Complications (1)
Cecal Diseases (11) · Digestive System Diseases (11) · Gastrointestinal Diseases (11) · Intestinal Diseases (11) · Gastroenteritis (10) · Intraabdominal Infections (10) · Infections (9) · Pathological Conditions, Signs and Symptoms (8) · Neurologic Manifestations (5) · Pathologic Processes (5) · Signs and Symptoms (5) · Pain (3) · Postoperative Complications (3) · Hernia (2) · Nervous System Diseases (2)
Appendectomy (5) · Bupivacaine (2) · Laparoscopy (2) · Anesthesia, General (1) · Exome Sequencing (1) · High-Throughput Nucleotide Sequencing (1) · Musculoskeletal Manipulations (1) · Nalbuphine (1) · Saline Solution (1) · Watchful Waiting (1)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ahmet Burak Doğan, MD (1) · Ain Shams University (1) · Akdeniz University (1) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Ayse Sonay Turkmen, Prof.Dr (1) · Bartın Unıversity (1) · Central Hospital, Nancy, France (1) · Centre Hospitalier Universitaire de Nice (1) · Dr. Asma Abdus Salam (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Herlev Hospital (1) · Hospital Galdakao-Usansolo (1) · Icahn School of Medicine at Mount Sinai (1) · Kocaeli City Hospital (1)
Turkey (Türkiye) (5) · Egypt (3) · Italy (3) · Pakistan (3) · Spain (2) · United States (2) · Benin (1) · Denmark (1) · France (1) · Ghana (1) · India (1) · Indonesia (1) · Mexico (1) · Netherlands (1) · Nigeria (1)
Ahmet Ergun, MD (1) · Aneel Bhangu (1) · Arun Jayaraman, PT, PhD (1) · Bakarne Ugarte-Sierra, PhD (1) · Charles D Adair, MD (1) · Fatma Dilek Turan, PhD (1) · Fizan Abdullah, MD, PhD (1) · Hassan Ghomrawi, PhD, MPH (1) · Linda P Zhang, MD (1) · Mauro Podda, M.D. (1) · Padillo R Javier, PhD (1) · Pareja C Felipe, PhD (1) · Reno Rudiman, Professor (1)
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R21TW012943 (1), R21TW012963 (1)